PDB entry 2vte
View 2vte on RCSB PDB site
Description: Crystal structure of MurD ligase in complex with D-Glu containing sulfonamide inhibitor
Class: ligase
Keywords: murd-inhibitor complex, peptidoglycan synthesis, nucleotide-binding, sulfonamide inhibitor, murd ligase, ATP-binding, cell division, ligase, cell shape, cell cycle, cell wall biogenesis/degradation
Deposited on
2008-05-14, released
2008-11-25
The last revision prior to the SCOPe 2.07 freeze date was dated
2011-12-28, with a file datestamp of
2011-12-23.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.212
AEROSPACI score: 0.38
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: udp-n-acetylmuramoylalanine--d-glutamate ligase
Species: Escherichia coli [TaxId:562]
Database cross-references and differences (RAF-indexed):
- Uniprot P14900 (Start-437)
- PDB 2VTE (438-End)
Domains in SCOPe 2.07: d2vtea1, d2vtea2, d2vtea3, d2vtea4 - Heterogens: IK4, SO4, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>2vteA (A:)
madyqgknvviiglgltglscvdfflargvtprvmdtrmtppgldklpeaverhtgslnd
ewlmaadlivaspgialahpslsaaadagieivgdielfcreaqapivaitgsngkstvt
tlvgemakaagvnvgvggniglpalmllddecelyvlelssfqlettsslqavaatilnv
tedhmdrypfglqqyraaklriyenakvcvvnaddaltmpirgadercvsfgvnmgdyhl
nhqqgetwlrvkgekvlnvkemklsgqhnytnalaalaladaaglprasslkalttftgl
phrfevvlehngvrwindskatnvgsteaalnglhvdgtlhlllggdgksadfsplaryl
ngdnvrlycfgrdgaqlaalrpevaeqtetmeqamrllaprvqpgdmvllspacasldqf
knfeqrgnefarlakelgshhhhhh
Sequence, based on observed residues (ATOM records): (download)
>2vteA (A:)
adyqgknvviiglgltglscvdfflargvtprvmdtrmtppgldklpeaverhtgslnde
wlmaadlivaspgialahpslsaaadagieivgdielfcreaqapivaitgsngkstvtt
lvgemakaagvnvgvggniglpalmllddecelyvlelssfqlettsslqavaatilnvt
edhmdrypfglqqyraaklriyenakvcvvnaddaltmpirercvsfgvnmgdyhlnhqe
twlrvkgekvlnvkemklsgqhnytnalaalaladaaglprasslkalttftglphrfev
vlehngvrwindskatnvgsteaalnglhvdgtlhlllggdgksadfsplarylngdnvr
lycfgrdgaqlaalrpevaeqtetmeqamrllaprvqpgdmvllspacasldqfknfeqr
gnefarlakelgsh