PDB entry 2vs6

View 2vs6 on RCSB PDB site
Description: k173a, r174a, k177a-trichosanthin
Class: hydrolase
Keywords: antiviral protein, protein synthesis inhibitor, tcs, toxin, hydrolase, plant defense
Deposited on 2008-04-21, released 2008-12-30
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-09-01, with a file datestamp of 2009-08-28.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.191
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ribosome-inactivating protein alpha-trichosanthin
    Species: TRICHOSANTHES KIRILOWII [TaxId:3677]
    Database cross-references and differences (RAF-indexed):
    • PDB 2VS6 (0-0)
      • engineered mutation (173-174)
      • engineered mutation (177)
    • Uniprot P09989 (1-End)
    Domains in SCOPe 2.05: d2vs6a_
  • Chain 'B':
    Compound: ribosome-inactivating protein alpha-trichosanthin
    Species: TRICHOSANTHES KIRILOWII [TaxId:3677]
    Database cross-references and differences (RAF-indexed):
    • PDB 2VS6 (0-0)
      • engineered mutation (173-174)
      • engineered mutation (177)
    • Uniprot P09989 (1-247)
    Domains in SCOPe 2.05: d2vs6b_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2vs6A (A:)
mdvsfrlsgatsssygvfisnlrkalpnerklydipllrsslpgsqryalihltnyadet
isvaidvtnvyimgyragdtsyffneasateaakyvfkdamrkvtlpysgnyerlqtaag
kireniplglpaldsaittlfyynansaasalmvliqstseaarykfieqqigaavdatf
lpslaiislenswsalskqiqiastnngqfespvvlinaqnqrvtitnvdagvvtsnial
llnrnnma

    Sequence, based on observed residues (ATOM records): (download) 
    >2vs6A (A:)
mdvsfrlsgatsssygvfisnlrkalpnerklydipllrsslpgsqryalihltnyadet
isvaidvtnvyimgyragdtsyffneasateaakyvfkdamrkvtlpysgnyerlqtaag
kireniplglpaldsaittlfyynansaasalmvliqstseaarykfieqqigaavdatf
lpslaiislenswsalskqiqiastnngqfespvvlinaqnqrvtitnvdagvvtsnial
llnrnnm

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2vs6B (B:)
mdvsfrlsgatsssygvfisnlrkalpnerklydipllrsslpgsqryalihltnyadet
isvaidvtnvyimgyragdtsyffneasateaakyvfkdamrkvtlpysgnyerlqtaag
kireniplglpaldsaittlfyynansaasalmvliqstseaarykfieqqigaavdatf
lpslaiislenswsalskqiqiastnngqfespvvlinaqnqrvtitnvdagvvtsnial
llnrnnma