PDB entry 2vs4

View 2vs4 on RCSB PDB site
Description: THE BINDING OF UDP-GALACTOSE BY AN ACTIVE SITE MUTANT OF alpha-1,3 GALACTOSYLTRANSFERASE (alpha3GT)
Class: transferase
Keywords: manganese, transferase, glycoprotein, metal-binding, active-site mutant, glycosyltransferase, n-acetyl lactosamine, signal-anchor, transmembrane, golgi apparatus, gt, udp, membrane, alpha3gt, galactose, alpha-3gt
Deposited on 2008-04-18, released 2008-07-15
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-06-29.
Experiment type: XRAY
Resolution: 1.77 Å
R-factor: N/A
AEROSPACI score: 0.46 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: n-acetyllactosaminide alpha-1,3-galactosyltransferase
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P14769 (Start-288)
      • engineered mutation (236)
    Domains in SCOPe 2.08: d2vs4a_
  • Chain 'B':
    Compound: n-acetyllactosaminide alpha-1,3-galactosyltransferase
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P14769 (Start-288)
      • engineered mutation (236)
    Domains in SCOPe 2.08: d2vs4b_
  • Heterogens: MN, UDP, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2vs4A (A:)
esklklsdwfnpfkrpevvtmtkwkapvvwegtynravldnyyakqkitvgltvfavgry
iehyleefltsankhfmvghpvifyimvddvsrmplielgplrsfkvfkikpekrwqdis
mmrmktigehivahiqhevdflfcmdvdqvfqdkfgvetlgesvaqlqawwykadpndft
yerrkesaayipfgegdfyyhaaifggtptqvlnitqecfkgilkdkkndieaqwheesh
lnkyfllnkptkilspeycwdyhiglpadiklvkmswqtkeynvvrnnv

    Sequence, based on observed residues (ATOM records): (download) 
    >2vs4A (A:)
sklklsdwfnpfkrpevvtmtkwkapvvwegtynravldnyyakqkitvgltvfavgryi
ehyleefltsankhfmvghpvifyimvddvsrmplielgplrsfkvfkikpekrwqdism
mrmktigehivahiqhevdflfcmdvdqvfqdkfgvetlgesvaqlqawwykadpndfty
errkesaayipfgegdfyyhaaifggtptqvlnitqecfkgilkdkkndieaqwheeshl
nkyfllnkptkilspeycwdyhiglpadiklvkmswqtkeynvvrnnv

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2vs4B (B:)
esklklsdwfnpfkrpevvtmtkwkapvvwegtynravldnyyakqkitvgltvfavgry
iehyleefltsankhfmvghpvifyimvddvsrmplielgplrsfkvfkikpekrwqdis
mmrmktigehivahiqhevdflfcmdvdqvfqdkfgvetlgesvaqlqawwykadpndft
yerrkesaayipfgegdfyyhaaifggtptqvlnitqecfkgilkdkkndieaqwheesh
lnkyfllnkptkilspeycwdyhiglpadiklvkmswqtkeynvvrnnv

    Sequence, based on observed residues (ATOM records): (download) 
    >2vs4B (B:)
sklklsdwfnpfkrpevvtmtkwkapvvwegtynravldnyyakqkitvgltvfavgryi
ehyleefltsankhfmvghpvifyimvddvsrmplielgplrsfkvfkikpekrwqdism
mrmktigehivahiqhevdflfcmdvdqvfqdkfgvetlgesvaqlqawwykadpndfty
errkesaayipfgegdfyyhaaifggtptqvlnitqecfkgilkdkkndieaqwheeshl
nkyfllnkptkilspeycwdyhiglpadiklvkmswqtkeynvvrnnv