PDB entry 2vpj

View 2vpj on RCSB PDB site
Description: Crystal structure of the Kelch domain of human KLHL12
Class: protein binding
Keywords: adaptor protein, wnt signaling pathway, protein-binding, ubiquitin degradation, ubl conjugation pathway, cul3, kelch repeat, phosphoprotein, wnt signalling, protein binding
Deposited on 2008-02-29, released 2008-03-18
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-01-24, with a file datestamp of 2018-01-19.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: N/A
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: kelch-like protein 12
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2VPJ
    • Uniprot Q53G59 (Start-300)
    Domains in SCOPe 2.08: d2vpja_
  • Heterogens: ACT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2vpjA (A:)
smqgprtrarlganevllvvggfgsqqspidvvekydpktqewsflpsitrkrryvasvs
lhdriyviggydgrsrlssvecldytadedgvwysvapmnvrrglagattlgdmiyvsgg
fdgsrrhtsmerydpnidqwsmlgdmqtaregaglvvasgviyclggydglnilnsveky
dphtghwtnvtpmatkrsgagvallndhiyvvggfdgtahlssveaynirtdswttvtsm
ttprcyvgatvlrgrlyaiagydgnsllssiecydpiidswevvtsmgtqrcdagvcvlr
e

    Sequence, based on observed residues (ATOM records): (download) 
    >2vpjA (A:)
anevllvvggfgsqqspidvvekydpktqewsflpsitrkrryvasvslhdriyviggyd
grsrlssvecldytadedgvwysvapmnvrrglagattlgdmiyvsggfdgsrrhtsmer
ydpnidqwsmlgdmqtaregaglvvasgviyclggydglnilnsvekydphtghwtnvtp
matkrsgagvallndhiyvvggfdgtahlssveaynirtdswttvtsmttprcyvgatvl
rgrlyaiagydgnsllssiecydpiidswevvtsmgtqrcdagvcvlre