PDB entry 2vpi

View 2vpi on RCSB PDB site
Description: human gmp synthetase - glutaminase domain
Class: ligase
Keywords: guanine monophosphate synthetase, phosphoprotein, gmp synthetase, gmp biosynthesis, glutamine amidotransferase, gmps, ligase, cytoplasm, ATP-binding, proto-oncogene, glutaminase domain, nucleotide-binding, purine biosynthesis, chromosomal rearrangement
Deposited on 2008-02-29, released 2008-03-11
The last revision prior to the SCOPe 2.04 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.206
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: GMP synthase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2VPI (Start-22)
    • Uniprot P49915 (23-217)
    Domains in SCOPe 2.04: d2vpia_
  • Chain 'B':
    Compound: GMP synthase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2VPI (Start-22)
    • Uniprot P49915 (23-217)
    Domains in SCOPe 2.04: d2vpib_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2vpiA (A:)
mhhhhhhssgvdlgtenlyfqsmegavvildagaqygkvidrrvrelfvqseifpletpa
faikeqgfraiiisggpnsvyaedapwfdpaiftigkpvlgicygmqmmnkvfggtvhkk
svredgvfnisvdntcslfrglqkeevvllthgdsvdkvadgfkvvarsgnivagianes
kklygaqfhpevgltengkvilknflydiagcsgtftv

    Sequence, based on observed residues (ATOM records): (download) 
    >2vpiA (A:)
megavvildagaqygkvidrrvrelfvqseifpletpafaikeqgfraiiisgapwfdpa
iftigkpvlgicygmqmmnkvfggtvhkksvredgvfnisvdntcslfrglqkeevvllt
hgdsvdkvadgfkvvarsgnivagianeskklygaqfhpevgltengkvilknflydiag
csgtftv

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2vpiB (B:)
mhhhhhhssgvdlgtenlyfqsmegavvildagaqygkvidrrvrelfvqseifpletpa
faikeqgfraiiisggpnsvyaedapwfdpaiftigkpvlgicygmqmmnkvfggtvhkk
svredgvfnisvdntcslfrglqkeevvllthgdsvdkvadgfkvvarsgnivagianes
kklygaqfhpevgltengkvilknflydiagcsgtftv

    Sequence, based on observed residues (ATOM records): (download) 
    >2vpiB (B:)
megavvildagaqygkvidrrvrelfvqseifpletpafaikeqgfraiiisgpwfdpai
ftigkpvlgicygmqmmnkvfggtvhkksvredgvfnisvdntcslfrglqkeevvllth
gdsvdkvadgfkvvarsgnivagianeskklygaqfhpevgltengkvilknflydiagc
sgtftv