PDB entry 2vp9

View 2vp9 on RCSB PDB site
Description: structural studies of nucleoside analog and feedback inhibitor binding to drosophila melanogaster multisubstrate deoxyribonucleoside kinase
Class: transferase
Keywords: ATP-binding, DNA synthesis, phosphoprotein, feedback inhibition, deoxyribonucleoside kinase, salvage pathway, nucleotide-binding, dttp, kinase, complex, drosophila, transferase
Deposited on 2008-02-27, released 2008-04-29
The last revision prior to the SCOP 1.75 freeze date was dated 2008-05-06, with a file datestamp of 2008-05-02.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: 0.24953
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: deoxynucleoside kinase
    Species: Drosophila melanogaster
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2vp9a1
  • Chain 'B':
    Compound: deoxynucleoside kinase
    Species: Drosophila melanogaster
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2vp9b1
  • Chain 'C':
    Compound: deoxynucleoside kinase
    Species: Drosophila melanogaster
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2vp9c1
  • Chain 'D':
    Compound: deoxynucleoside kinase
    Species: Drosophila melanogaster
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2vp9d1
  • Chain 'E':
    Compound: deoxynucleoside kinase
    Species: Drosophila melanogaster
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2vp9e1
  • Chain 'F':
    Compound: deoxynucleoside kinase
    Species: Drosophila melanogaster
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2vp9f1
  • Chain 'G':
    Compound: deoxynucleoside kinase
    Species: Drosophila melanogaster
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2vp9g1
  • Chain 'H':
    Compound: deoxynucleoside kinase
    Species: Drosophila melanogaster
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2vp9h1
  • Heterogens: SO4, DOC, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2vp9A (A:)
maeaascarkgtkyaegtqpftvliegnigsgkttylnhfekykndiclltepvekwrnv
ngvnllelmykdpkkwampfqsyvtltmlqshtaptnkklkimersifsarycfvenmrr
ngsleqgmyntleewykfieesihvqadliiylrtspevayerirqrarseescvplkyl
qelhelhedwlihqrrpqsckvlvldadlnlenigteyqrsessifdais

    Sequence, based on observed residues (ATOM records): (download) 
    >2vp9A (A:)
tkyaegtqpftvliegnigsgkttylnhfekykndiclltepvekwrnvngvnllelmyk
dpkkwampfqsyvtltmlqshtaptnkklkimersifsarycfvenmrrngsleqgmynt
leewykfieesihvqadliiylrtspevayerirqrarseescvplkylqelhelhedwl
ihqrrpqsckvlvldad

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2vp9B (B:)
maeaascarkgtkyaegtqpftvliegnigsgkttylnhfekykndiclltepvekwrnv
ngvnllelmykdpkkwampfqsyvtltmlqshtaptnkklkimersifsarycfvenmrr
ngsleqgmyntleewykfieesihvqadliiylrtspevayerirqrarseescvplkyl
qelhelhedwlihqrrpqsckvlvldadlnlenigteyqrsessifdais

    Sequence, based on observed residues (ATOM records): (download) 
    >2vp9B (B:)
tkyaegtqpftvliegnigsgkttylnhfekykndiclltepvekwrnvngvnllelmyk
dpkkwampfqsyvtltmlqshtaptnkklkimersifsarycfvenmrrngsleqgmynt
leewykfieesihvqadliiylrtspevayerirqrarseescvplkylqelhelhedwl
ihqckvlvldad

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2vp9C (C:)
maeaascarkgtkyaegtqpftvliegnigsgkttylnhfekykndiclltepvekwrnv
ngvnllelmykdpkkwampfqsyvtltmlqshtaptnkklkimersifsarycfvenmrr
ngsleqgmyntleewykfieesihvqadliiylrtspevayerirqrarseescvplkyl
qelhelhedwlihqrrpqsckvlvldadlnlenigteyqrsessifdais

    Sequence, based on observed residues (ATOM records): (download) 
    >2vp9C (C:)
tkyaegtqpftvliegnigsgkttylnhfekykndiclltepvekwrnvngvnllelmyk
dpkkwampfqsyvtltmlqshtaptnkklkimersifsarycfvenmrrngsleqgmynt
leewykfieesihvqadliiylrtspevayerirqrarseescvplkylqelhelhedwl
ihqrrpqsckvlvldad

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2vp9D (D:)
maeaascarkgtkyaegtqpftvliegnigsgkttylnhfekykndiclltepvekwrnv
ngvnllelmykdpkkwampfqsyvtltmlqshtaptnkklkimersifsarycfvenmrr
ngsleqgmyntleewykfieesihvqadliiylrtspevayerirqrarseescvplkyl
qelhelhedwlihqrrpqsckvlvldadlnlenigteyqrsessifdais

    Sequence, based on observed residues (ATOM records): (download) 
    >2vp9D (D:)
tkyaegtqpftvliegnigsgkttylnhfekykndiclltepvekwrnvngvnllelmyk
dpkkwampfqsyvtltmlqshtaptnkklkimersifsarycfvenmrrngsleqgmynt
leewykfieesihvqadliiylrtspevayerirqrarseescvplkylqelhelhedwl
ihckvlvldad

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2vp9E (E:)
maeaascarkgtkyaegtqpftvliegnigsgkttylnhfekykndiclltepvekwrnv
ngvnllelmykdpkkwampfqsyvtltmlqshtaptnkklkimersifsarycfvenmrr
ngsleqgmyntleewykfieesihvqadliiylrtspevayerirqrarseescvplkyl
qelhelhedwlihqrrpqsckvlvldadlnlenigteyqrsessifdais

    Sequence, based on observed residues (ATOM records): (download) 
    >2vp9E (E:)
tkyaegtqpftvliegnigsgkttylnhfekykndiclltepvekwrnvngvnllelmyk
dpkkwampfqsyvtltmlqshtaptnkklkimersifsarycfvenmrrngsleqgmynt
leewykfieesihvqadliiylrtspevayerirqrarseescvplkylqelhelhedwl
ihqckvlvldad

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >2vp9F (F:)
maeaascarkgtkyaegtqpftvliegnigsgkttylnhfekykndiclltepvekwrnv
ngvnllelmykdpkkwampfqsyvtltmlqshtaptnkklkimersifsarycfvenmrr
ngsleqgmyntleewykfieesihvqadliiylrtspevayerirqrarseescvplkyl
qelhelhedwlihqrrpqsckvlvldadlnlenigteyqrsessifdais

    Sequence, based on observed residues (ATOM records): (download) 
    >2vp9F (F:)
tkyaegtqpftvliegnigsgkttylnhfekykndiclltepvekwrnvngvnllelmyk
dpkkwampfqsyvtltmlqshtaptnkklkimersifsarycfvenmrrngsleqgmynt
leewykfieesihvqadliiylrtspevayerirqrarseescvplkylqelhelhedwl
ihqckvlvldad

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >2vp9G (G:)
maeaascarkgtkyaegtqpftvliegnigsgkttylnhfekykndiclltepvekwrnv
ngvnllelmykdpkkwampfqsyvtltmlqshtaptnkklkimersifsarycfvenmrr
ngsleqgmyntleewykfieesihvqadliiylrtspevayerirqrarseescvplkyl
qelhelhedwlihqrrpqsckvlvldadlnlenigteyqrsessifdais

    Sequence, based on observed residues (ATOM records): (download) 
    >2vp9G (G:)
tkyaegtqpftvliegnigsgkttylnhfekykndiclltepvekwrnvngvnllelmyk
dpkkwampfqsyvtltmlqshtaptnkklkimersifsarycfvenmrrngsleqgmynt
leewykfieesihvqadliiylrtspevayerirqrarseescvplkylqelhelhedwl
ihqckvlvldad

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >2vp9H (H:)
maeaascarkgtkyaegtqpftvliegnigsgkttylnhfekykndiclltepvekwrnv
ngvnllelmykdpkkwampfqsyvtltmlqshtaptnkklkimersifsarycfvenmrr
ngsleqgmyntleewykfieesihvqadliiylrtspevayerirqrarseescvplkyl
qelhelhedwlihqrrpqsckvlvldadlnlenigteyqrsessifdais

    Sequence, based on observed residues (ATOM records): (download) 
    >2vp9H (H:)
tkyaegtqpftvliegnigsgkttylnhfekykndiclltepvekwrnvngvnllelmyk
dpkkwampfqsyvtltmlqshtaptnkklkimersifsarycfvenmrrngsleqgmynt
leewykfieesihvqadliiylrtspevayerirqrarseescvplkylqelhelhedwl
ihqckvlvldad