PDB entry 2vp5

View 2vp5 on RCSB PDB site
Description: structural studies of nucleoside analog and feedback inhibitor binding to drosophila melanogaster multisubstrate deoxyribonucleoside kinase
Class: transferase
Keywords: ATP-binding, DNA synthesis, phosphoprotein, feedback inhibition, deoxyribonucleoside kinase, salvage pathway, nucleotide-binding, dttp, kinase, complex, drosophila, transferase
Deposited on 2008-02-26, released 2008-04-18
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.236
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: deoxynucleoside kinase
    Species: Drosophila melanogaster [TaxId:7227]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2vp5a_
  • Chain 'B':
    Compound: deoxynucleoside kinase
    Species: Drosophila melanogaster [TaxId:7227]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2vp5b_
  • Heterogens: SO4, DCZ, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2vp5A (A:)
maeaascarkgtkyaegtqpftvliegnigsgkttylnhfekykndiclltepvekwrnv
ngvnllelmykdpkkwampfqsyvtltmlqshtaptnkklkimersifsarycfvenmrr
ngsleqgmyntleewykfieesihvqadliiylrtspevayerirqrarseescvplkyl
qelhelhedwlihqrrpqsckvlvldadlnlenigteyqrsessifdais

    Sequence, based on observed residues (ATOM records): (download) 
    >2vp5A (A:)
tqpftvliegnigsgkttylnhfekykndiclltepvekwrnvngvnllelmykdpkkwa
mpfqsyvtltmlqshtaptnkklkimersifsarycfvenmrrngsleqgmyntleewyk
fieesihvqadliiylrtspevayerirqrarseescvplkylqelhelhedwlihqrrp
qsckvlvldad

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2vp5B (B:)
maeaascarkgtkyaegtqpftvliegnigsgkttylnhfekykndiclltepvekwrnv
ngvnllelmykdpkkwampfqsyvtltmlqshtaptnkklkimersifsarycfvenmrr
ngsleqgmyntleewykfieesihvqadliiylrtspevayerirqrarseescvplkyl
qelhelhedwlihqrrpqsckvlvldadlnlenigteyqrsessifdais

    Sequence, based on observed residues (ATOM records): (download) 
    >2vp5B (B:)
tqpftvliegnigsgkttylnhfekykndiclltepvekwrnvngvnllelmykdpkkwa
mpfqsyvtltmlqshtaptnkklkimersifsarycfvenmrrngsleqgmyntleewyk
fieesihvqadliiylrtspevayerirqrarseescvplkylqelhelhedwlihckvl
vldad