PDB entry 2vp4

View 2vp4 on RCSB PDB site
Description: structural studies of nucleoside analog and feedback inhibitor binding to drosophila melanogaster multisubstrate deoxyribonucleoside kinase
Class: transferase
Keywords: ATP-binding, DNA synthesis, phosphoprotein, feedback inhibition, deoxyribonucleoside kinase, salvage pathway, nucleotide-binding, dttp, kinase, complex, drosophila, transferase
Deposited on 2008-02-26, released 2008-04-29
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.197
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: deoxynucleoside kinase
    Species: Drosophila melanogaster [TaxId:7227]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2vp4a_
  • Chain 'B':
    Compound: deoxynucleoside kinase
    Species: Drosophila melanogaster [TaxId:7227]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2vp4b_
  • Chain 'C':
    Compound: deoxynucleoside kinase
    Species: Drosophila melanogaster [TaxId:7227]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2vp4c_
  • Chain 'D':
    Compound: deoxynucleoside kinase
    Species: Drosophila melanogaster [TaxId:7227]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2vp4d_
  • Heterogens: DCP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2vp4A (A:)
maeaascarkgtkyaegtqpftvliegnigsgkttylnhfekykndiclltepvekwrnv
ngvnllelmykdpkkwampfqsyvtltmlqshtaptnkklkimersifsarycfvenmrr
ngsleqgmyntleewykfieesihvqadliiylrtspevayerirqrarseescvplkyl
qelhelhedwlihqrrpqsckvlvldadlnlenigteyqrsessifdais

    Sequence, based on observed residues (ATOM records): (download) 
    >2vp4A (A:)
tkyaegtqpftvliegnigsgkttylnhfekykndiclltepvekwrnvngvnllelmyk
dpkkwampfqsyvtltmlqshtaptnkklkimersifsarycfvenmrrngsleqgmynt
leewykfieesihvqadliiylrtspevayerirqrarseescvplkylqelhelhedwl
ihqrrpqsckvlvldadl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2vp4B (B:)
maeaascarkgtkyaegtqpftvliegnigsgkttylnhfekykndiclltepvekwrnv
ngvnllelmykdpkkwampfqsyvtltmlqshtaptnkklkimersifsarycfvenmrr
ngsleqgmyntleewykfieesihvqadliiylrtspevayerirqrarseescvplkyl
qelhelhedwlihqrrpqsckvlvldadlnlenigteyqrsessifdais

    Sequence, based on observed residues (ATOM records): (download) 
    >2vp4B (B:)
tkyaegtqpftvliegnigsgkttylnhfekykndiclltepvekwrnvngvnllelmyk
dpkkwampfqsyvtltmlqshtaptnkklkimersifsarycfvenmrrngsleqgmynt
leewykfieesihvqadliiylrtspevayerirqrarseescvplkylqelhelhedwl
ihqrrpqsckvlvldadl

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2vp4C (C:)
maeaascarkgtkyaegtqpftvliegnigsgkttylnhfekykndiclltepvekwrnv
ngvnllelmykdpkkwampfqsyvtltmlqshtaptnkklkimersifsarycfvenmrr
ngsleqgmyntleewykfieesihvqadliiylrtspevayerirqrarseescvplkyl
qelhelhedwlihqrrpqsckvlvldadlnlenigteyqrsessifdais

    Sequence, based on observed residues (ATOM records): (download) 
    >2vp4C (C:)
tkyaegtqpftvliegnigsgkttylnhfekykndiclltepvekwrnvngvnllelmyk
dpkkwampfqsyvtltmlqshtaptnkklkimersifsarycfvenmrrngsleqgmynt
leewykfieesihvqadliiylrtspevayerirqrarseescvplkylqelhelhedwl
ihqrrpqsckvlvldad

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2vp4D (D:)
maeaascarkgtkyaegtqpftvliegnigsgkttylnhfekykndiclltepvekwrnv
ngvnllelmykdpkkwampfqsyvtltmlqshtaptnkklkimersifsarycfvenmrr
ngsleqgmyntleewykfieesihvqadliiylrtspevayerirqrarseescvplkyl
qelhelhedwlihqrrpqsckvlvldadlnlenigteyqrsessifdais

    Sequence, based on observed residues (ATOM records): (download) 
    >2vp4D (D:)
tkyaegtqpftvliegnigsgkttylnhfekykndiclltepvekwrnvngvnllelmyk
dpkkwampfqsyvtltmlqshtaptnkklkimersifsarycfvenmrrngsleqgmynt
leewykfieesihvqadliiylrtspevayerirqrarseescvplkylqelhelhedwl
ihqrrpqsckvlvldadln