PDB entry 2voh

View 2voh on RCSB PDB site
Description: structure of mouse a1 bound to the bak bh3-domain
Class: apoptosis
Keywords: bh3, bcl-2, membrane, apoptosis, pro-survival, transmembrane, protein-protein complex
Deposited on 2008-02-17, released 2008-03-04
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-31.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.185
AEROSPACI score: 0.51 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: bcl-2-related protein a1
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 2VOH (0-4)
      • engineered mutation (108)
      • engineered mutation (117)
    • Uniprot Q07440 (5-End)
    Domains in SCOPe 2.07: d2voha1, d2voha2
  • Chain 'B':
    Compound: bcl-2 homologous antagonist/killer
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: CIT, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2vohA (A:)
gplgsmaeselmhihslaehylqyvlqvpafesapsqacrvlqrvafsvqkeveknlksy
lddfhvesidtariifnqvmekefedgiinwgrivtifafggvllkklkqeqialdvsay
kqvssfvaefimnntgewirqnggwedgfikkfepks

    Sequence, based on observed residues (ATOM records): (download) 
    >2vohA (A:)
gplgsmaeselmhihslaehylqyvlqvpafesapsqacrvlqrvafsvqkeveknlksy
lddfhvesidtariifnqvmekefedgiinwgrivtifafggvllkklkqeqialdvsay
kqvssfvaefimnntgewirqnggwedgfikkfep

  • Chain 'B':
    No sequence available.