PDB entry 2vof
View 2vof on RCSB PDB site
Description: structure of mouse a1 bound to the puma bh3-domain
Class: apoptosis
Keywords: bh3, bcl-2, apoptosis, pro-survival, mitochondrion, protein-protein complex
Deposited on
2008-02-17, released
2008-03-04
The last revision prior to the SCOPe 2.08 freeze date was dated
2011-07-13, with a file datestamp of
2011-05-31.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.184
AEROSPACI score: 0.55
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: bcl-2-related protein a1
Species: Mus musculus [TaxId:10090]
Database cross-references and differences (RAF-indexed):
- PDB 2VOF (Start-4)
- engineered mutation (108)
- engineered mutation (117)
- Uniprot Q07440 (5-End)
Domains in SCOPe 2.08: d2vofa1, d2vofa2 - Chain 'B':
Compound: Bcl-2-binding component 3
Species: Mus musculus [TaxId:10090]
Database cross-references and differences (RAF-indexed):
- Chain 'C':
Compound: bcl-2-related protein a1
Species: Mus musculus [TaxId:10090]
Database cross-references and differences (RAF-indexed):
- PDB 2VOF (Start-4)
- engineered mutation (108)
- engineered mutation (117)
- Uniprot Q07440 (5-End)
Domains in SCOPe 2.08: d2vofc1, d2vofc2 - Chain 'D':
Compound: Bcl-2-binding component 3
Species: Mus musculus [TaxId:10090]
Database cross-references and differences (RAF-indexed):
- Heterogens: CL, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>2vofA (A:)
gplgsmaeselmhihslaehylqyvlqvpafesapsqacrvlqrvafsvqkeveknlksy
lddfhvesidtariifnqvmekefedgiinwgrivtifafggvllkklkqeqialdvsay
kqvssfvaefimnntgewirqnggwedgfikkfepks
Sequence, based on observed residues (ATOM records): (download)
>2vofA (A:)
gsmaeselmhihslaehylqyvlqvpafeapsqacrvlqrvafsvqkeveknlksylddf
hvesidtariifnqvmekefedgiinwgrivtifafggvllkklkqesaykqvssfvaef
imnntgewirqnggwedgfikkfep
- Chain 'B':
No sequence available.
- Chain 'C':
Sequence, based on SEQRES records: (download)
>2vofC (C:)
gplgsmaeselmhihslaehylqyvlqvpafesapsqacrvlqrvafsvqkeveknlksy
lddfhvesidtariifnqvmekefedgiinwgrivtifafggvllkklkqeqialdvsay
kqvssfvaefimnntgewirqnggwedgfikkfepks
Sequence, based on observed residues (ATOM records): (download)
>2vofC (C:)
lgsmaeselmhihslaehylqyvlqvpafepsqacrvlqrvafsvqkeveknlksylddf
hvesidtariifnqvmekefedgiinwgrivtifafggvllkklkqeqialdvsaykqvs
sfvaefimnntgewirqnggwedgfikkfe
- Chain 'D':
No sequence available.