PDB entry 2vny
View 2vny on RCSB PDB site
Description: structure of pka-pkb chimera complexed with (1-(9h-purin-6-yl)piperidin-4-yl)amine
Class: transferase
Keywords: transferase, lipoprotein, ATP-binding, phosphoprotein, serine/threonine-protein kinase, nucleotide-binding, protein kinase inhibitor, camp, kinase, nucleus, myristate, cytoplasm
Deposited on
2008-02-08, released
2008-04-08
The last revision prior to the SCOPe 2.05 freeze date was dated
2009-02-24, with a file datestamp of
2009-03-01.
Experiment type: XRAY
Resolution: 1.96 Å
R-factor: 0.226
AEROSPACI score: 0.43
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: cAMP-dependent protein kinase, alpha-catalytic subunit
Species: Bos taurus [TaxId:9913]
Database cross-references and differences (RAF-indexed):
- Uniprot P00517 (Start-350)
- engineered mutation (104)
- engineered mutation (123)
- engineered mutation (173)
- engineered mutation (181)
Domains in SCOPe 2.05: d2vnya_ - Chain 'I':
Compound: cAMP-dependent protein kinase inhibitor alpha
Species: HOMO SAPIENS, synthetic [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Heterogens: M02, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>2vnyA (A:)
mgnaaaakkgseqesvkeflakakedflkkwenpaqntahldqferiktlgtgsfgrvml
vkhmetgnhyamkildkqkvvklkqiehtlnekrilqavnfpfltklefsfkdnsnlymv
meyapggemfshlrrigrfsepharfyaaqivltfeylhsldliyrdlkpenlmidqqgy
ikvtdfgfakrvkgrtwtlcgtpeylapeiilskgynkavdwwalgvliyemaagyppff
adqpiqiyekivsgkvrfpshfssdlkdllrnllqvdltkrfgnlkngvndiknhkwfat
tdwiaiyqrkveapfipkfkgpgdtsnfddyeeeeirvsinekcgkefsef
Sequence, based on observed residues (ATOM records): (download)
>2vnyA (A:)
svkeflakakedflkkwenpaqntahldqferiktlgtgsfgrvmlvkhmetgnhyamki
ldkqkvvklkqiehtlnekrilqavnfpfltklefsfkdnsnlymvmeyapggemfshlr
rigrfsepharfyaaqivltfeylhsldliyrdlkpenlmidqqgyikvtdfgfakrvkg
rtwtlcgtpeylapeiilskgynkavdwwalgvliyemaagyppffadqpiqiyekivsg
kvrfpshfssdlkdllrnllqvdltkrfgnlkngvndiknhkwfattdwiaiyqrkveap
fipkfkgpgdtsnfddyeeeeirvsinekcgkefsef
- Chain 'I':
No sequence available.