PDB entry 2vnt

View 2vnt on RCSB PDB site
Description: urokinase-type plasminogen activator inhibitor complex with a 1-(7-sulphoamidoisoquinolinyl)guanidine
Deposited on 2008-02-07, released 2008-02-19
The last revision was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.244
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: urokinase-type plasminogen activator
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: urokinase-type plasminogen activator
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: urokinase-type plasminogen activator
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: urokinase-type plasminogen activator
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: urokinase-type plasminogen activator
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: urokinase-type plasminogen activator
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: QGG, SO4, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >2vntA (A:)
kpssppeelkfqcgqktlrprfkiiggefttienqpwfaaiyrrhrggsvtyvcggslms
pcwvisathcfidypkkedyivylgrsrlnsntqgemkfevenlilhkdysadtlahhnd
iallkirskegrcaqpsrtiqticlpsmyndpqfgtsceitgfgkenstdylypeqlkmt
vvklishrecqqphyygsevttkmlcaadpqwktdscqgdsggplvcslqgrmtltgivs
wgrgcalkdkpgvytrvshflpwirshtkeenglal

    Sequence, based on observed residues (ATOM records):
    >2vntA (A:)
kfqcgqktliiggefttienqpwfaaiyrrhrggsvtyvcggslmspcwvisathcfidy
pkkedyivylgrsrlnsntqgemkfevenlilhkdysadtlahhndiallkirskegrca
qpsrtiqticlpsmyndpqfgtsceitgfgkenstdylypeqlkmtvvklishrecqqph
yygsevttkmlcaadpqwktdscqgdsggplvcslqgrmtltgivswgrgcalkdkpgvy
trvshflpwirshtkeen

  • Chain 'B':
    Sequence, based on SEQRES records:
    >2vntB (B:)
kpssppeelkfqcgqktlrprfkiiggefttienqpwfaaiyrrhrggsvtyvcggslms
pcwvisathcfidypkkedyivylgrsrlnsntqgemkfevenlilhkdysadtlahhnd
iallkirskegrcaqpsrtiqticlpsmyndpqfgtsceitgfgkenstdylypeqlkmt
vvklishrecqqphyygsevttkmlcaadpqwktdscqgdsggplvcslqgrmtltgivs
wgrgcalkdkpgvytrvshflpwirshtkeenglal

    Sequence, based on observed residues (ATOM records):
    >2vntB (B:)
lkfqcgqktliiggefttienqpwfaaiyrrhrggsvtyvcggslmspcwvisathcfid
ypkkedyivylgrsrlnsntqgemkfevenlilhkdysadtlahhndiallkirskegrc
aqpsrtiqticlpsmyndpqfgtsceitgfgkenstdylypeqlkmtvvklishrecqqp
hyygsevttkmlcaadpqwktdscqgdsggplvcslqgrmtltgivswgrgcalkdkpgv
ytrvshflpwirshtkeen

  • Chain 'C':
    Sequence, based on SEQRES records:
    >2vntC (C:)
kpssppeelkfqcgqktlrprfkiiggefttienqpwfaaiyrrhrggsvtyvcggslms
pcwvisathcfidypkkedyivylgrsrlnsntqgemkfevenlilhkdysadtlahhnd
iallkirskegrcaqpsrtiqticlpsmyndpqfgtsceitgfgkenstdylypeqlkmt
vvklishrecqqphyygsevttkmlcaadpqwktdscqgdsggplvcslqgrmtltgivs
wgrgcalkdkpgvytrvshflpwirshtkeenglal

    Sequence, based on observed residues (ATOM records):
    >2vntC (C:)
fqcgqktlrpiiggefttienqpwfaaiyrrhrggsvtyvcggslmspcwvisathcfid
ypkkedyivylgrsrlnsntqgemkfevenlilhkdysadtlahhndiallkirskegrc
aqpsrtiqticlpsmyndpqfgtsceitgfgkenstdylypeqlkmtvvklishrecqqp
hyygsevttkmlcaadpqwktdscqgdsggplvcslqgrmtltgivswgrgcalkdkpgv
ytrvshflpwirshtkeen

  • Chain 'D':
    Sequence, based on SEQRES records:
    >2vntD (D:)
kpssppeelkfqcgqktlrprfkiiggefttienqpwfaaiyrrhrggsvtyvcggslms
pcwvisathcfidypkkedyivylgrsrlnsntqgemkfevenlilhkdysadtlahhnd
iallkirskegrcaqpsrtiqticlpsmyndpqfgtsceitgfgkenstdylypeqlkmt
vvklishrecqqphyygsevttkmlcaadpqwktdscqgdsggplvcslqgrmtltgivs
wgrgcalkdkpgvytrvshflpwirshtkeenglal

    Sequence, based on observed residues (ATOM records):
    >2vntD (D:)
lkfqcgqktliiggefttienqpwfaaiyrrhrggsvtyvcggslmspcwvisathcfid
ypkkedyivylgrsrlnsntqgemkfevenlilhkdysadtlahhndiallkirskegrc
aqpsrtiqticlpsmyndpqfgtsceitgfgkenstdylypeqlkmtvvklishrecqqp
hyygsevttkmlcaadpqwktdscqgdsggplvcslqgrmtltgivswgrgcalkdkpgv
ytrvshflpwirshtkeen

  • Chain 'E':
    Sequence, based on SEQRES records:
    >2vntE (E:)
kpssppeelkfqcgqktlrprfkiiggefttienqpwfaaiyrrhrggsvtyvcggslms
pcwvisathcfidypkkedyivylgrsrlnsntqgemkfevenlilhkdysadtlahhnd
iallkirskegrcaqpsrtiqticlpsmyndpqfgtsceitgfgkenstdylypeqlkmt
vvklishrecqqphyygsevttkmlcaadpqwktdscqgdsggplvcslqgrmtltgivs
wgrgcalkdkpgvytrvshflpwirshtkeenglal

    Sequence, based on observed residues (ATOM records):
    >2vntE (E:)
lkfqcgqktliiggefttienqpwfaaiyrrhrggsvtyvcggslmspcwvisathcfid
ypkkedyivylgrsrlnsntqgemkfevenlilhkdysadtlahhndiallkirskegrc
aqpsrtiqticlpsmyndpqfgtsceitgfgkenstdylypeqlkmtvvklishrecqqp
hyygsevttkmlcaadpqwktdscqgdsggplvcslqgrmtltgivswgrgcalkdkpgv
ytrvshflpwirshtkeen

  • Chain 'F':
    Sequence, based on SEQRES records:
    >2vntF (F:)
kpssppeelkfqcgqktlrprfkiiggefttienqpwfaaiyrrhrggsvtyvcggslms
pcwvisathcfidypkkedyivylgrsrlnsntqgemkfevenlilhkdysadtlahhnd
iallkirskegrcaqpsrtiqticlpsmyndpqfgtsceitgfgkenstdylypeqlkmt
vvklishrecqqphyygsevttkmlcaadpqwktdscqgdsggplvcslqgrmtltgivs
wgrgcalkdkpgvytrvshflpwirshtkeenglal

    Sequence, based on observed residues (ATOM records):
    >2vntF (F:)
cgqktlrpiiggefttienqpwfaaiyrrhrggsvtyvcggslmspcwvisathcfidyp
kkedyivylgrsrlnsntqgemkfevenlilhkdysadtlahhndiallkirskegrcaq
psrtiqticlpsmyndpqfgtsceitgfgkenstdylypeqlkmtvvklishrecqqphy
ygsevttkmlcaadpqwktdscqgdsggplvcslqgrmtltgivswgrgcalkdkpgvyt
rvshflpwirshtkeen