PDB entry 2vls

View 2vls on RCSB PDB site
Description: structure of the hsp90 inhibitor macbecin bound to the n-terminus of yeast hsp90.
Class: cell cycle
Keywords: chaperone/complex, chaperone-complex, cell cycle, chaperone, cytoplasm, inhibitor, heat shock, ATP-binding, stress response, multigene family, nucleotide-binding
Deposited on 2008-01-16, released 2008-04-08
The last revision prior to the SCOPe 2.08 freeze date was dated 2008-07-01, with a file datestamp of 2008-06-27.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.18572
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ATP-dependent molecular chaperone hsp82
    Species: SACCHAROMYCES CEREVISIAE
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2vlsa_
  • Heterogens: BC2, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2vlsA (A:)
masetfefqaeitqlmsliintvysnkeiflrelisnasdaldkirykslsdpkqletep
dlfiritpkpeqkvleirdsgigmtkaelinnlgtiaksgtkafmealsagadvsmigqf
gvgfyslflvadrvqvisksnddeqyiwesnaggsftvtldevnerigrgtilrlflkdd
qleyleekrikevikrhsefvaypiqlvvtkevekevpi

    Sequence, based on observed residues (ATOM records): (download) 
    >2vlsA (A:)
asetfefqaeitqlmsliintvysnkeiflrelisnasdaldkirykslsdpkqletepd
lfiritpkpeqkvleirdsgigmtkaelinnlgtiaksgtkafmealsagadvsmigqfg
vgfyslflvadrvqvisksnddeqyiwesnaggsftvtldevnerigrgtilrlflkddq
leyleekrikevikrhsefvaypiqlvvtkevek