PDB entry 2vlk
View 2vlk on RCSB PDB site
Description: the structural dynamics and energetics of an immunodominant T-cell receptor are programmed by its vbeta domain
Class: immune system
Keywords: glycoprotein, transmembrane, ubl conjugation, immune system/receptor/complex, immunoglobulin domain, host-virus interaction, pyrrolidone carboxylic acid, immune response, immunodominance, disease mutation, membrane, secreted, receptor, glycation, polymorphism, tcr, flu, MHC, MHC I, T-cell, peptide, complex
Deposited on
2008-01-15, released
2008-01-22
The last revision prior to the SCOP 1.75 freeze date was dated
2008-02-26, with a file datestamp of
2008-02-22.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.22131
AEROSPACI score: 0.34
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: HLA class I histocompatibility antigen, A-2 alpha chain
Species: HOMO SAPIENS
Database cross-references and differences (RAF-indexed):
Domains in SCOP 1.75: d2vlka1, d2vlka2 - Chain 'B':
Compound: Beta-2-microglobulin
Species: HOMO SAPIENS
Database cross-references and differences (RAF-indexed):
- PDB 2VLK (1-End)
- Uniprot P61769 (1-99)
Domains in SCOP 1.75: d2vlkb1 - Chain 'C':
Compound: flu matrix peptide
- Chain 'D':
Compound: jm22 tcr alpha chain
Species: HOMO SAPIENS
- Chain 'E':
Compound: jm22 tcr beta chain
Species: HOMO SAPIENS
Domains in SCOP 1.75: d2vlke1, d2vlke2 - Heterogens: HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>2vlkA (A:)
gshsmryfftsvsrpgrgeprfiavgyvddtqfvrfdsdaasqrmeprapwieqegpeyw
dgetrkvkahsqthrvdlgtlrgyynqseagshtvqrmygcdvgsdwrflrgyhqyaydg
kdyialkedlrswtaadmaaqttkhkweaahvaeqlraylegtcvewlrrylengketlq
rtdapkthmthhavsdheatlrcwalsfypaeitltwqrdgedqtqdtelvetrpagdgt
fqkwaavvvpsgqeqrytchvqheglpkpltlrwep
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>2vlkB (B:)
miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
- Chain 'C':
No sequence available.
- Chain 'D':
No sequence available.
- Chain 'E':
Sequence, based on SEQRES records: (download)
>2vlkE (E:)
mvdggitqspkylfrkegqnvtlsceqnlnhdamywyrqdpgqglrliyysqivndfqkg
diaegysvsrekkesfpltvtsaqknptafylcasssrssyeqyfgpgtrltvtedlknv
fppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvstdpqplkeq
palndsryslssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaeaw
grad
Sequence, based on observed residues (ATOM records): (download)
>2vlkE (E:)
gitqspkylfrkegqnvtlsceqnlnhdamywyrqdpgqglrliyysqivndfqkgdiae
gysvsrekkesfpltvtsaqknptafylcasssrssyeqyfgpgtrltvtedlknvfppe
vavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvstdpqplkeqpaln
dsryslssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaeawgrad