PDB entry 2vlk

View 2vlk on RCSB PDB site
Description: the structural dynamics and energetics of an immunodominant T-cell receptor are programmed by its vbeta domain
Class: immune system
Keywords: glycoprotein, transmembrane, ubl conjugation, immune system/receptor/complex, immunoglobulin domain, host-virus interaction, pyrrolidone carboxylic acid, immune response, immunodominance, disease mutation, membrane, secreted, receptor, glycation, polymorphism, tcr, flu, MHC, MHC I, T-cell, peptide, complex
Deposited on 2008-01-15, released 2008-01-22
The last revision prior to the SCOP 1.75 freeze date was dated 2008-02-26, with a file datestamp of 2008-02-22.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.22131
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: HLA class I histocompatibility antigen, A-2 alpha chain
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2vlka1, d2vlka2
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed):
    • PDB 2VLK (1-End)
    • Uniprot P61769 (1-99)
    Domains in SCOP 1.75: d2vlkb1
  • Chain 'C':
    Compound: flu matrix peptide
  • Chain 'D':
    Compound: jm22 tcr alpha chain
    Species: HOMO SAPIENS
  • Chain 'E':
    Compound: jm22 tcr beta chain
    Species: HOMO SAPIENS
    Domains in SCOP 1.75: d2vlke1, d2vlke2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2vlkA (A:)
    gshsmryfftsvsrpgrgeprfiavgyvddtqfvrfdsdaasqrmeprapwieqegpeyw
    dgetrkvkahsqthrvdlgtlrgyynqseagshtvqrmygcdvgsdwrflrgyhqyaydg
    kdyialkedlrswtaadmaaqttkhkweaahvaeqlraylegtcvewlrrylengketlq
    rtdapkthmthhavsdheatlrcwalsfypaeitltwqrdgedqtqdtelvetrpagdgt
    fqkwaavvvpsgqeqrytchvqheglpkpltlrwep
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2vlkB (B:)
    miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
    wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
    

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    Sequence, based on SEQRES records: (download)
    >2vlkE (E:)
    mvdggitqspkylfrkegqnvtlsceqnlnhdamywyrqdpgqglrliyysqivndfqkg
    diaegysvsrekkesfpltvtsaqknptafylcasssrssyeqyfgpgtrltvtedlknv
    fppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvstdpqplkeq
    palndsryslssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaeaw
    grad
    

    Sequence, based on observed residues (ATOM records): (download)
    >2vlkE (E:)
    gitqspkylfrkegqnvtlsceqnlnhdamywyrqdpgqglrliyysqivndfqkgdiae
    gysvsrekkesfpltvtsaqknptafylcasssrssyeqyfgpgtrltvtedlknvfppe
    vavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvstdpqplkeqpaln
    dsryslssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaeawgrad