PDB entry 2vki

View 2vki on RCSB PDB site
Description: structure of the pdk1 ph domain k465e mutant
Class: transferase
Keywords: pleckstrin homology, transferase, cancer, diabetes
Deposited on 2007-12-19, released 2008-05-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-31.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.175
AEROSPACI score: 0.52 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 3-phopshoinositide dependent protein kinase 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O15530
      • engineered mutation (56)
    Domains in SCOPe 2.08: d2vkia_
  • Heterogens: GOL, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2vkiA (A:)
gsnieqyihdldsnsfeldlqfsedekrlllekqaggnpwhqfvennlilkmgpvderkg
lfarrrqllltegphlyyvdpvnkvlkgeipwsqelrpeaknfktffvhtpnrtyylmdp
sgnahkwcrkiqevwrqryqshpdaavq

    Sequence, based on observed residues (ATOM records): (download) 
    >2vkiA (A:)
snieqyihdldsnsfeldlqfsedekrlllekqaggnpwhqfvennlilkmgpvderkgl
farrrqllltegphlyyvdpvnkvlkgeipwsqelrpeaknfktffvhtpnrtyylmdps
gnahkwcrkiqevwrqryqs