PDB entry 2vje

View 2vje on RCSB PDB site
Description: crystal structure of the mdm2-mdmx ring domain heterodimer
Deposited on 2007-12-10, released 2008-05-13
The last revision was dated 2018-06-06, with a file datestamp of 2018-06-01.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: E3 ubiquitin-protein ligase Mdm2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: mdm4 protein
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: E3 ubiquitin-protein ligase Mdm2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: mdm4 protein
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: ZN, FLC, SO4, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >2vjeA (A:)
sslplnaiepcvicqgrpkngcivhgktghlmacftcakklkkrnkpcpvcrqpiqmivl
tyfp

    Sequence, based on observed residues (ATOM records):
    >2vjeA (A:)
lnaiepcvicqgrpkngcivhgktghlmacftcakklkkrnkpcpvcrqpiqmivltyfp

  • Chain 'B':
    Sequence, based on SEQRES records:
    >2vjeB (B:)
edcqnllkpcslcekrprdgniihgrtghlvtcfhcarrlkkagascpickkeiqlvikv
fia

    Sequence, based on observed residues (ATOM records):
    >2vjeB (B:)
cqnllkpcslcekrprdgniihgrtghlvtcfhcarrlkkagascpickkeiqlvikvfi
a

  • Chain 'C':
    Sequence, based on SEQRES records:
    >2vjeC (C:)
sslplnaiepcvicqgrpkngcivhgktghlmacftcakklkkrnkpcpvcrqpiqmivl
tyfp

    Sequence, based on observed residues (ATOM records):
    >2vjeC (C:)
lnaiepcvicqgrpkngcivhgktghlmacftcakklkkrnkpcpvcrqpiqmivltyfp

  • Chain 'D':
    Sequence, based on SEQRES records:
    >2vjeD (D:)
edcqnllkpcslcekrprdgniihgrtghlvtcfhcarrlkkagascpickkeiqlvikv
fia

    Sequence, based on observed residues (ATOM records):
    >2vjeD (D:)
dcqnllkpcslcekrprdgniihgrtghlvtcfhcarrlkkagascpickkeiqlvikvf
ia