PDB entry 2vj0
View 2vj0 on RCSB PDB site
Description: crystal structure of the alpha-adaptin appendage domain, from the ap2 adaptor complex, in complex with an fxdnf peptide from amphiphysin1 and a wvxf peptide from synaptojanin p170
Class: protein transport
Keywords: protein transport, cytoplasmic vesicle, alternative splicing, transport, coated pit, sh3 domain, endocytosis, alpha-adaptin, golgi apparatus, phosphorylation, ap2, synapse, membrane, cytoplasm, coiled coil, amphiphysin, cytoskeleton, synaptojanin, lipid-binding, cell junction
Deposited on
2007-12-06, released
2007-12-25
The last revision prior to the SCOPe 2.08 freeze date was dated
2009-02-24, with a file datestamp of
2009-03-01.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: 0.182
AEROSPACI score: 0.6
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: ap-2 complex subunit alpha-2
Species: Mus musculus [TaxId:10090]
Database cross-references and differences (RAF-indexed):
- PDB 2VJ0
- conflict (5)
- conflict (98)
- conflict (200-201)
- Uniprot P17427 (4-249)
Domains in SCOPe 2.08: d2vj0a1, d2vj0a2 - Chain 'P':
Compound: synaptojanin-1
Species: HOMO SAPIENS, synthetic [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Chain 'Q':
Compound: amphiphysin
Species: RATTUS NORVEGICUS, synthetic [TaxId:10116]
Database cross-references and differences (RAF-indexed):
- Heterogens: BEN, DTD, SO4, CL, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>2vj0A (A:)
gspgilaplapgsednfarfvcknngvlfenqllqiglksefrqnlgrmfifygnktstq
flnftptlicaddlqtnlnlqtkpvdptvdggaqvqqviniecisdfteapvlniqfryg
gtfqnvsvklpitlnkffqptemasqdffqrwkqlsnpqqevqnifkakhpmdteitkak
iigfgsalleevdpnpanfvgagiihtkttqigcllrlepnlqaqmyrltlrtskdtvsq
rlcellseqf
Sequence, based on observed residues (ATOM records): (download)
>2vj0A (A:)
ilaplapgsednfarfvcknngvlfenqllqiglksefrqnlgrmfifygnktstqflnf
tptlicaddlqtnlnlqtkpvdptvdggaqvqqviniecisdfteapvlniqfryggtfq
nvsvklpitlnkffqptemasqdffqrwkqlsnpqqevqnifkakhpmdteitkakiigf
gsalleevdpnpanfvgagiihtkttqigcllrlepnlqaqmyrltlrtskdtvsqrlce
llseqf
- Chain 'P':
No sequence available.
- Chain 'Q':
No sequence available.