PDB entry 2vhv

View 2vhv on RCSB PDB site
Description: crystal structure of the d270a mutant of l-alanine dehydrogenase from mycobacterium tuberculosis in complex with nadh.
Deposited on 2007-11-26, released 2008-03-11
The last revision was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.202
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: alanine dehydrogenase
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P30234 (0-370)
      • engineered mutation (269)
    • PDB 2VHV
  • Chain 'B':
    Compound: alanine dehydrogenase
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P30234 (0-370)
      • engineered mutation (269)
    • PDB 2VHV
  • Heterogens: NAI, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >2vhvA (A:)
mrvgiptetknnefrvaitpagvaeltrrghevliqagagegsaitdadfkaagaqlvgt
adqvwadadlllkvkepiaaeygrlrhgqilftflhlaasractdalldsgttsiayetv
qtadgalpllapmsevagrlaaqvgayhlmrtqggrgvlmggvpgvepadvvvigagtag
ynaariangmgatvtvldinidklrqldaefcgrihtryssayelegavkradlvigavl
vpgakapklvsnslvahmkpgavlvdiainqggcfegsrpttydhptfavhdtlfycvan
mpasvpktstyaltnatmpyvleladhgwraacrsnpalakglsthegallservatdlg
vpftepasvlahhhhhh

    Sequence, based on observed residues (ATOM records):
    >2vhvA (A:)
mrvgiptetknnefrvaitpagvaeltrrghevliqagagegsaitdadfkaagaqlvgt
adqvwadadlllkvkepiaaeygrlrhgqilftflhlaasractdalldsgttsiayetv
qtadgalpllapmsevagrlaaqvgayhlmrtqggrgvlmggvpgvepadvvvigagtag
ynaariangmgatvtvldinidklrqldaefcgrihtryssayelegavkradlvigavl
vpgakapklvsnslvahmkpgavlvdiainqggcfegsrpttydhptfavhdtlfycvan
mpasvpktstyaltnatmpyvleladhgwraacrsnpalakglsthegallservatdlg
vpftepasvla

  • Chain 'B':
    Sequence, based on SEQRES records:
    >2vhvB (B:)
mrvgiptetknnefrvaitpagvaeltrrghevliqagagegsaitdadfkaagaqlvgt
adqvwadadlllkvkepiaaeygrlrhgqilftflhlaasractdalldsgttsiayetv
qtadgalpllapmsevagrlaaqvgayhlmrtqggrgvlmggvpgvepadvvvigagtag
ynaariangmgatvtvldinidklrqldaefcgrihtryssayelegavkradlvigavl
vpgakapklvsnslvahmkpgavlvdiainqggcfegsrpttydhptfavhdtlfycvan
mpasvpktstyaltnatmpyvleladhgwraacrsnpalakglsthegallservatdlg
vpftepasvlahhhhhh

    Sequence, based on observed residues (ATOM records):
    >2vhvB (B:)
mrvgiptetknnefrvaitpagvaeltrrghevliqagagegsaitdadfkaagaqlvgt
adqvwadadlllkvkepiaaeygrlrhgqilftflhlaasractdalldsgttsiayetv
qtadgalpllapmsevagrlaaqvgayhlmrtqggrgvlmggvpgvepadvvvigagtag
ynaariangmgatvtvldinidklrqldaefcgrihtryssayelegavkradlvigavl
vpgakapklvsnslvahmkpgavlvdiainqggcfegsrpttydhptfavhdtlfycvan
mpasvpktstyaltnatmpyvleladhgwraacrsnpalakglsthegallservatdlg
vpftepasvla