PDB entry 2vhs

View 2vhs on RCSB PDB site
Description: cathsilicatein, a chimera
Deposited on 2007-11-24, released 2008-03-11
The last revision was dated 2011-07-13, with a file datestamp of 2011-05-31.
Experiment type: XRAY
Resolution: 1.5 Å
R-factor: 0.19
AEROSPACI score: 0.62 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: cathsilicatein
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P07711 (177-216)
      • conflict (109)
      • engineered mutation (23-25)
      • engineered mutation (152-153)
      • engineered mutation (158-161)
      • engineered mutation (163-164)
    • PDB 2VHS (172-176)
  • Chain 'B':
    Compound: cathsilicatein
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P07711 (177-216)
      • conflict (109)
      • engineered mutation (23-25)
      • engineered mutation (152-153)
      • engineered mutation (158-161)
      • engineered mutation (163-164)
    • PDB 2VHS (172-176)
  • Chain 'C':
    Compound: cathsilicatein
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P07711 (177-216)
      • conflict (109)
      • engineered mutation (23-25)
      • engineered mutation (152-153)
      • engineered mutation (158-161)
      • engineered mutation (163-164)
    • PDB 2VHS (172-176)
  • Chain 'D':
    Compound: cathsilicatein
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P07711 (177-216)
      • conflict (109)
      • engineered mutation (23-25)
      • engineered mutation (152-153)
      • engineered mutation (158-161)
      • engineered mutation (163-164)
    • PDB 2VHS (172-176)
  • Heterogens: SO4, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >2vhsA (A:)
aprsvdwrekgyvtpvknqgqcgasyafsatgalegqmfrktgrlislseqnlvdcsgpq
gnegcngglmdyafqyvqdnggldseesypyeateesckynpkysvandvgfvdipkqek
almkavatvgpisvaidaghesflfykegiyfssdcsssslnhamlvvgygfisnnqkyw
lvknswgeewgmggyvkmakdrrnhcgiasaasyptv

    Sequence, based on observed residues (ATOM records):
    >2vhsA (A:)
aprsvdwrekgyvtpvknqgqcgasyafsatgalegqmfrktgrlislseqnlvdcsgpq
gnegcngglmdyafqyvqdnggldseesypyeateesckynpkysvandvgfvdipkqek
almkavatvgpisvaidaghesflfykegiyfssdcsssslnhamlvvgygfisqkywlv
knswgeewgmggyvkmakdrrnhcgiasaasyptv

  • Chain 'B':
    Sequence, based on SEQRES records:
    >2vhsB (B:)
aprsvdwrekgyvtpvknqgqcgasyafsatgalegqmfrktgrlislseqnlvdcsgpq
gnegcngglmdyafqyvqdnggldseesypyeateesckynpkysvandvgfvdipkqek
almkavatvgpisvaidaghesflfykegiyfssdcsssslnhamlvvgygfisnnqkyw
lvknswgeewgmggyvkmakdrrnhcgiasaasyptv

    Sequence, based on observed residues (ATOM records):
    >2vhsB (B:)
aprsvdwrekgyvtpvknqgqcgasyafsatgalegqmfrktgrlislseqnlvdcsgpq
gnegcngglmdyafqyvqdnggldseesypyeateesckynpkysvandvgfvdipkqek
almkavatvgpisvaidaghesflfykegiyfssdcsssslnhamlvvgygfisqkywlv
knswgeewgmggyvkmakdrrnhcgiasaasyptv

  • Chain 'C':
    Sequence, based on SEQRES records:
    >2vhsC (C:)
aprsvdwrekgyvtpvknqgqcgasyafsatgalegqmfrktgrlislseqnlvdcsgpq
gnegcngglmdyafqyvqdnggldseesypyeateesckynpkysvandvgfvdipkqek
almkavatvgpisvaidaghesflfykegiyfssdcsssslnhamlvvgygfisnnqkyw
lvknswgeewgmggyvkmakdrrnhcgiasaasyptv

    Sequence, based on observed residues (ATOM records):
    >2vhsC (C:)
aprsvdwrekgyvtpvknqgqcgasyafsatgalegqmfrktgrlislseqnlvdcsgpq
gnegcngglmdyafqyvqdnggldseesypyeateesckynpkysvandvgfvdipkqek
almkavatvgpisvaidaghesflfykegiyfssdcsssslnhamlvvgygfisqkywlv
knswgeewgmggyvkmakdrrnhcgiasaasyptv

  • Chain 'D':
    Sequence, based on SEQRES records:
    >2vhsD (D:)
aprsvdwrekgyvtpvknqgqcgasyafsatgalegqmfrktgrlislseqnlvdcsgpq
gnegcngglmdyafqyvqdnggldseesypyeateesckynpkysvandvgfvdipkqek
almkavatvgpisvaidaghesflfykegiyfssdcsssslnhamlvvgygfisnnqkyw
lvknswgeewgmggyvkmakdrrnhcgiasaasyptv

    Sequence, based on observed residues (ATOM records):
    >2vhsD (D:)
aprsvdwrekgyvtpvknqgqcgasyafsatgalegqmfrktgrlislseqnlvdcsgpq
gnegcngglmdyafqyvqdnggldseesypyeateesckynpkysvandvgfvdipkqek
almkavatvgpisvaidaghesflfykegiyfssdcsssslnhamlvvgygfisqkywlv
knswgeewgmggyvkmakdrrnhcgiasaasyptv