PDB entry 2vh5
View 2vh5 on RCSB PDB site
Description: crystal structure of hras(g12v) - anti-ras fv (disulfide free mutant) complex
Class: immune system
Keywords: immunoglobulin domain, signaling protein/immune system, methylation, prenylation, lipoprotein, GTP-binding, signal transduction, nucleotide- binding, disease mutation, nucleotide-binding, immune system, membrane, oncogene, antibody, palmitate, intrabody, proto-oncogene, cancer therapy, golgi apparatus
Deposited on
2007-11-19, released
2008-01-22
The last revision prior to the SCOPe 2.07 freeze date was dated
2009-02-24, with a file datestamp of
2009-03-01.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.215
AEROSPACI score: 0.27
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'H':
Compound: anti-ras fv heavy chain
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.07: d2vh5h_ - Chain 'L':
Compound: anti-ras fv light chain
Species: Homo sapiens [TaxId:9606]
Domains in SCOPe 2.07: d2vh5l_ - Chain 'R':
Compound: gtpase hras
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.07: d2vh5r_ - Heterogens: ZN, GTP, MG, HOH
PDB Chain Sequences:
- Chain 'H':
Sequence; same for both SEQRES and ATOM records: (download)
>2vh5H (H:)
evqllesggglvqpggslrlsaaasgftfstfsmnwvrqapgkglewvsyisrtsktiyy
adsvkgrftisrdnskntlylqmnslraedtavyyvargrffdywgqgtlvtvs
- Chain 'L':
Sequence; same for both SEQRES and ATOM records: (download)
>2vh5L (L:)
iqmtqspsslsasvgdrvtitvrasqsissylnwyqqkpgeapklliysasvlqsgvpsr
fsgsgsgtdftltisslqpedfatyyaqqsvmipmtfgqgtkve
- Chain 'R':
Sequence; same for both SEQRES and ATOM records: (download)
>2vh5R (R:)
mteyklvvvgavgvgksaltiqliqnhfvdeydptiedsyrkqvvidgetclldildtag
qeeysamrdqymrtgegflcvfainntksfedihqyreqikrvkdsddvpmvlvgnkcdl
aartvesrqaqdlarsygipyietsaktrqgvedafytlvreirqh