PDB entry 2vgl

View 2vgl on RCSB PDB site
Description: ap2 clathrin adaptor core
Class: protein transport
Keywords: cytoplasmic vesicle, alternative splicing, endocytosis, lipid-binding, golgi apparatus, adaptor, membrane, transport, coated pit, phosphorylation, protein transport
Deposited on 2007-11-14, released 2007-12-25
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.59 Å
R-factor: 0.265
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: adaptor protein complex ap-2, alpha 2 subunit
    Species: Rattus norvegicus [TaxId:10116]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2vgla_
  • Chain 'B':
    Compound: AP-2 complex subunit beta-1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2vglb_
  • Chain 'M':
    Compound: ap-2 complex subunit mu-1
    Species: Rattus norvegicus [TaxId:10116]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2vglm1
  • Chain 'S':
    Compound: ap-2 complex subunit sigma-1
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2vgls_
  • Heterogens: IHP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2vglA (A:)
mpavskgegmrglavfisdirnckskeaeikrinkelanirskfkgdkaldgyskkkyvc
kllfifllghdidfghmeavnllssnrytekqigylfisvlvnsnselirlinnaikndl
asrnptfmglalhcianvgsremaeafageipkilvagdtmdsvkqsaalcllrlyrtsp
dlvpmgdwtsrvvhllndqhlgvvtaatslittlaqknpeefktsvslavsrlsrivtsa
stdlqdytyyfvpapwlsvkllrllqcypppedpavrgrltecletilnkaqeppkskkv
qhsnaknavlfeaisliihhdsepnllvracnqlgqflqhretnlrylalesmctlasse
fsheavkthietvinalkterdvsvrqravdllyamcdrsnaqqivaemlsyletadysi
reeivlkvailaekyavdytwyvdtilnliriagdyvseevwyrviqivinrddvqgyaa
ktvfealqapachenlvkvggyilgefgnliagdprsspliqfnllhskfhlcsvptral
llstyikfvnlfpevkatiqdvlrsdsqlknadvelqqraveylrlstvastdilatvle
emppfperessilaklkkkkg

    Sequence, based on observed residues (ATOM records): (download) 
    >2vglA (A:)
gmrglavfisdirnckskeaeikrinkelanirskfkgdkaldgyskkkyvckllfifll
ghdidfghmeavnllssnrytekqigylfisvlvnsnselirlinnaikndlasrnptfm
glalhcianvgsremaeafageipkilvagdtmdsvkqsaalcllrlyrtspdlvpmgdw
tsrvvhllndqhlgvvtaatslittlaqknpeefktsvslavsrlsrivtsastdlqdyt
yyfvpapwlsvkllrllqcypppedpavrgrltecletilnkaqeppkskkvqhsnakna
vlfeaisliihhdsepnllvracnqlgqflqhretnlrylalesmctlassefsheavkt
hietvinalkterdvsvrqravdllyamcdrsnaqqivaemlsyletadysireeivlkv
ailaekyavdytwyvdtilnliriagdyvseevwyrviqivinrddvqgyaaktvfealq
apachenlvkvggyilgefgnliagdprsspliqfnllhskfhlcsvptralllstyikf
vnlfpevkatiqdvlrsdsqlknadvelqqraveylrlstvastdilatvleemppfper

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2vglB (B:)
mtdskyfttnkkgeifelkaelnnekkekrkeavkkviaamtvgkdvsslfpdvvncmqt
dnlelkklvylylmnyaksqpdmaimavnsfvkdcedpnpliralavrtmgcirvdkite
ylceplrkclkdedpyvrktaavcvaklhdinaqmvedqgfldslrdliadsnpmvvana
vaalseiseshpnsnlldlnpqninklltalnectewgqifildclsnynpkddreaqsi
cervtprlshansavvlsavkvlmkflellpkdsdyynmllkklapplvtllsgepevqy
valrninlivqkrpeilkqeikvffvkyndpiyvklekldimirlasqaniaqvlaelke
yatevdvdfvrkavraigrcaikveqsaercvstlldliqtkvnyvvqeaivvirdifrk
ypnkyesiiatlcenldsldepdaraamiwivgeyaeridnadellesflegfhdestqv
qltlltaivklflkkpsetqelvqqvlslatqdsdnpdlrdrgyiywrllstdpvtakev
vlsekpliseetdlieptlldelichigslasvyhkppnafvegshgihrk

    Sequence, based on observed residues (ATOM records): (download) 
    >2vglB (B:)
skyfttnkkgeifelkaelnnekkekrkeavkkviaamtvgkdvsslfpdvvncmqtdnl
elkklvylylmnyaksqpdmaimavnsfvkdcedpnpliralavrtmgcirvdkiteylc
eplrkclkdedpyvrktaavcvaklhdinaqmvedqgfldslrdliadsnpmvvanavaa
lseiseshpnsnlldlnpqninklltalnectewgqifildclsnynpkddreaqsicer
vtprlshansavvlsavkvlmkflellpkdsdyynmllkklapplvtllsgepevqyval
rninlivqkrpeilkqeikvffvkyndpiyvklekldimirlasqaniaqvlaelkeyat
evdvdfvrkavraigrcaikveqsaercvstlldliqtkvnyvvqeaivvirdifrkypn
kyesiiatlcenldsldepdaraamiwivgeyaeridnadellesflegfhdestqvqlt
lltaivklflkkpsetqelvqqvlslatqdsdnpdlrdrgyiywrllstdpvtakevvls
ekpliseetdlieptlldelichigslasvyhkppnafv

  • Chain 'M':
    Sequence, based on SEQRES records: (download) 
    >2vglM (M:)
migglfiynhkgevlisrvyrddigrnavdafrvnviharqqvrspvtniartsffhvkr
sniwlaavtkqnvnaamvfeflykmcdvmaayfgkiseeniknnfvliyelldeildfgy
pqnsetgalktfitqqgiksqhqtkeeqsqitsqvtgqigwrregikyrrnelfldvles
vnllmspqgqvlsahvsgrvvmksylsgmpeckfgmndkiviekqgkgtadetsksgkqs
iaiddctfhqcvrlskfdsersisfippdgefelmryrttkdiilpfrviplvrevgrtk
levkvviksnfkpsllaqkievriptplntsgvqvicmkgkakykasenaivwkikrmag
mkesqisaeiellptndkkkwarppismnfevpfapsglkvrylkvfepklnysdhdvik
wvryigrsgiyetrc

    Sequence, based on observed residues (ATOM records): (download) 
    >2vglM (M:)
migglfiynhkgevlisrvyrddigrnavdafrvnviharqqvrspvtniartsffhvkr
sniwlaavtkqnvnaamvfeflykmcdvmaayfgkiseeniknnfvliyelldeildfgy
pqnsetgalktfitqqgiksqigwrregikyrrnelfldvlesvnllmspqgqvlsahvs
grvvmksylsgmpeckfgmndkivisiaiddctfhqcvrlsrsisfippdgefelmryrt
tkdiilpfrviplvrevgrtklevkvviksnfkpsllaqkievriptplntsgvqvicmk
gkakykasenaivwkikrmagmkesqisaeiellptndkkkwarppismnfevpfapsgl
kvrylkvfepklnysdhdvikwvryigrsgiyetrc

  • Chain 'S':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2vglS (S:)
mirfiliqnragktrlakwymqfdddekqklieevhavvtvrdakhtnfvefrnfkiiyr
ryaglyfcicvdvndnnlayleaihnfvevlneyfhnvceldlvfnfykvytvvdemfla
geiretsqtkvlkqllmlqsle