PDB entry 2ves

View 2ves on RCSB PDB site
Description: crystal structure of lpxc from pseudomonas aeruginosa complexed with the potent bb-78485 inhibitor
Deposited on 2007-10-26, released 2008-01-15
The last revision was dated 2019-05-08, with a file datestamp of 2019-05-03.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: UDP-3-O-acyl-N-acetylglucosamine deacetylase
    Species: Pseudomonas aeruginosa [TaxId:208964]
    Gene: lpxC, envA, PA4406
    Database cross-references and differences (RAF-indexed):
    • Uniprot P47205 (0-End)
      • conflict (39)
  • Chain 'B':
    Compound: UDP-3-O-acyl-N-acetylglucosamine deacetylase
    Species: Pseudomonas aeruginosa [TaxId:208964]
    Gene: lpxC, envA, PA4406
    Database cross-references and differences (RAF-indexed):
    • Uniprot P47205 (0-End)
      • conflict (39)
  • Chain 'C':
    Compound: UDP-3-O-acyl-N-acetylglucosamine deacetylase
    Species: Pseudomonas aeruginosa [TaxId:208964]
    Gene: lpxC, envA, PA4406
    Database cross-references and differences (RAF-indexed):
    • Uniprot P47205 (0-298)
      • conflict (39)
  • Heterogens: ZN, GVR, SO4, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >2vesA (A:)
mikqrtlkniiratgvglhsgekvyltlkpapvdtgivfsrtdldpvveiparaenvget
tmsttlvkgdvkvdtvehllsamaglgidnayvelsasevpimdgsagpfvfliqsaglq
eqeaakkfirikrevsveegdkravfvpfdgfkvsfeidfdhpvfrgrtqqasvdfssts
fvkevsrartfgfmrdieylrsqnlalggsvenaivvdenrvlnedglryedefvkhkil
daigdlyllgnsligefrgfksghalnnqllrtliadkdawevvtfedartapisymrp

    Sequence, based on observed residues (ATOM records):
    >2vesA (A:)
mikqrtlkniiratgvglhsgekvyltlkpapvdtgivfsrtdldpvveiparaenvget
tmsttlvkgdvkvdtvehllsamaglgidnayvelsasevpimdgsagpfvfliqsaglq
eqeaakkfirikrevsveegdkravfvpfdgfkvsfeidfdhpvfrgrtqqasvdfssts
fvkevsrartfgfmrdieylrsqnlalggsvenaivvdenrvlnedglryedefvkhkil
daigdlyllgnsligefrgfksghalnnqllrtliadkdawevvtfedartapi

  • Chain 'B':
    Sequence, based on SEQRES records:
    >2vesB (B:)
mikqrtlkniiratgvglhsgekvyltlkpapvdtgivfsrtdldpvveiparaenvget
tmsttlvkgdvkvdtvehllsamaglgidnayvelsasevpimdgsagpfvfliqsaglq
eqeaakkfirikrevsveegdkravfvpfdgfkvsfeidfdhpvfrgrtqqasvdfssts
fvkevsrartfgfmrdieylrsqnlalggsvenaivvdenrvlnedglryedefvkhkil
daigdlyllgnsligefrgfksghalnnqllrtliadkdawevvtfedartapisymrp

    Sequence, based on observed residues (ATOM records):
    >2vesB (B:)
mikqrtlkniiratgvglhsgekvyltlkpapvdtgivfsrtdldpvveiparaenvget
tmsttlvkgdvkvdtvehllsamaglgidnayvelsasevpimdgsagpfvfliqsaglq
eqeaakkfirikrevsveegdkravfvpfdgfkvsfeidfdhpvfrgrtqqasvdfssts
fvkevsrartfgfmrdieylrsqnlalggsvenaivvdenrvlnedglryedefvkhkil
daigdlyllgnsligefrgfksghalnnqllrtliadkdawevvtfed

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records:
    >2vesC (C:)
mikqrtlkniiratgvglhsgekvyltlkpapvdtgivfsrtdldpvveiparaenvget
tmsttlvkgdvkvdtvehllsamaglgidnayvelsasevpimdgsagpfvfliqsaglq
eqeaakkfirikrevsveegdkravfvpfdgfkvsfeidfdhpvfrgrtqqasvdfssts
fvkevsrartfgfmrdieylrsqnlalggsvenaivvdenrvlnedglryedefvkhkil
daigdlyllgnsligefrgfksghalnnqllrtliadkdawevvtfedartapisymrp