PDB entry 2vdb

View 2vdb on RCSB PDB site
Description: structure of human serum albumin with s-naproxen and the ga module
Class: protein binding
Keywords: lipid-binding, metal-binding, protein binding, peptidoglycan-anchor, bacterial albumin-binding, disease mutation, three-helix bundle, ga module, drug binding, glycoprotein, cleavage on pair of basic residues, human serum albumin, secreted, naproxen, cell wall, glycation
Deposited on 2007-10-04, released 2008-02-26
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-31.
Experiment type: XRAY
Resolution: 2.52 Å
R-factor: 0.236
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: serum albumin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2vdba1, d2vdba2, d2vdba3
  • Chain 'B':
    Compound: peptostreptococcal albumin-binding protein
    Species: PEPTOSTREPTOCOCCUS MAGNUS [TaxId:1260]
    Database cross-references and differences (RAF-indexed):
    • PDB 2VDB (0-1)
    • Uniprot Q51911 (2-54)
    Domains in SCOPe 2.07: d2vdbb_
  • Heterogens: DKA, NPS

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2vdbA (A:)
    evahrfkdlgeenfkalvliafaqylqqcpfedhvklvnevtefaktcvadesaencdks
    lhtlfgdklctvatlretygemadccakqepernecflqhkddnpnlprlvrpevdvmct
    afhdneetflkkylyeiarrhpyfyapellffakrykaafteccqaadkaacllpkldel
    rdegkassakqrlkcaslqkfgerafkawavarlsqrfpkaefaevsklvtdltkvhtec
    chgdllecaddradlakyicenqdsissklkeccekpllekshciaevendempadlpsl
    aadfveskdvcknyaeakdvflgmflyeyarrhpdysvvlllrlaktyettlekccaaad
    phecyakvfdefkplveepqnlikqncelfeqlgeykfqnallvrytkkvpqvstptlve
    vsrnlgkvgskcckhpeakrmpcaedylsvvlnqlcvlhektpvsdrvtkccteslvnrr
    pcfsalevdetyvpkefnaetftfhadictlsekerqikkqtalvelvkhkpkatkeqlk
    avmddfaafvekcckaddketcfaeegkklvaasqaalg
    

    Sequence, based on observed residues (ATOM records): (download)
    >2vdbA (A:)
    evahrfkdlgeenfkalvliafaqylqqcpfedhvklvnevtefaktcvadesaencdks
    lhtlfgdklctvatlemadccakqepernecflqhkddnpnlprlvrpevdvmctafhdn
    eetflkkylyeiarrhpyfyapellffakrykaafteccqaadkaacllpkldelrdegk
    assakqrlkcaslqkfgerafkawavarlsqrfpkaefaevsklvtdltkvhtecchgdl
    lecaddradlakyicenqdsissklkeccekpllekshciaevendempadlpslaadfv
    eskdvcknyaeakdvflgmflyeyarrhpdysvvlllrlaktyettlekccaaadphecy
    akvfdefkplveepqnlikqncelfeqlgeykfqnallvrytkkvpqvstptlvevsrnl
    gkvgskcckhpeakrmpcaedylsvvlnqlcvlhektpvsdrvtkccteslvnrrpcfsa
    levdetyvpkefnaetftfhadictlsekerqikkqtalvelvkhkpkatkeqlkavmdd
    faafvekcckaddketcfaeegkklvaasqaalg
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2vdbB (B:)
    hmtidqwllknakedaiaelkkagitsdfyfnainkaktveevnalkneilkaha