PDB entry 2vcs

View 2vcs on RCSB PDB site
Description: Structure of isoniazid (INH) bound to cytosolic soybean ascorbate peroxidase mutant H42A
Class: oxidoreductase
Keywords: ascorbate peroxidase, peroxidase, inh, apx, isoniazid, oxidoreductase
Deposited on 2007-09-26, released 2007-12-04
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-07-05, with a file datestamp of 2017-06-30.
Experiment type: XRAY
Resolution: 1.68 Å
R-factor: N/A
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ascorbate peroxidase
    Species: Glycine max [TaxId:3847]
    Database cross-references and differences (RAF-indexed):
    • PDB 2VCS
      • engineered mutation (52)
    • Uniprot Q43758 (12-260)
    Domains in SCOPe 2.08: d2vcsa_
  • Heterogens: HEM, ISZ, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2vcsA (A:)
mrgshhhhhhgsgksyptvsadyqkavekakkklrgfiaekrcaplmlrlawasagtfdk
gtktggpfgtikhpaelahsanngldiavrlleplkaefpilsyadfyqlagvvavevtg
gpevpfhpgredkpepppegrlpdatkgsdhlrdvfgkamgltdqdivalsgghtigaah
kersgfegpwtsnplifdnsyftellsgekegllqlpsdkallsdpvfrplvdkyaaded
affadyaeahqklselgfada

    Sequence, based on observed residues (ATOM records): (download) 
    >2vcsA (A:)
gksyptvsadyqkavekakkklrgfiaekrcaplmlrlawasagtfdkgtktggpfgtik
hpaelahsanngldiavrlleplkaefpilsyadfyqlagvvavevtggpevpfhpgred
kpepppegrlpdatkgsdhlrdvfgkamgltdqdivalsgghtigaahkersgfegpwts
nplifdnsyftellsgekegllqlpsdkallsdpvfrplvdkyaadedaffadyaeahqk
lselgfada