PDB entry 2vbl

View 2vbl on RCSB PDB site
Description: Molecular basis of human XPC gene recognition and cleavage by engineered homing endonuclease heterodimers
Class: hydrolase
Keywords: uv-induced DNA damage, cutting DNA endonucleases, nuclease, hydrolase, chloroplast, endonuclease, intron homing, amel3- 4_magnesium, double strand break (dsb), homing endonucleases (hes)
Deposited on 2007-09-14, released 2008-10-28
The last revision prior to the SCOPe 2.08 freeze date was dated 2012-06-20, with a file datestamp of 2012-06-15.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.149
AEROSPACI score: 0.53 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA endonuclease I-crei
    Species: Chlamydomonas reinhardtii [TaxId:3055]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P05725 (Start-152)
      • conflict (27)
      • conflict (30)
      • conflict (37)
      • conflict (39)
      • conflict (41)
      • conflict (43)
      • conflict (69)
      • conflict (74)
      • conflict (84)
      • conflict (108-110)
    Domains in SCOPe 2.08: d2vbla_
  • Chain 'B':
    Compound: DNA endonuclease I-crei
    Species: Chlamydomonas reinhardtii [TaxId:3055]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P05725 (Start-152)
      • conflict (18)
      • conflict (27)
      • conflict (32)
      • conflict (37)
      • conflict (39)
      • conflict (41)
      • conflict (68-69)
      • conflict (74)
      • conflict (109-110)
    Domains in SCOPe 2.08: d2vblb_
  • Chain 'C':
    Compound: 5'-d(*dt*dc*dt*dg*dc*dc*dt*dt*dt*dt*dt*dt *dgp*dap)-3'
  • Chain 'E':
    Compound: 5'-d(*dt*dt*da*dg*dg*da*dt*dc*dc*dt*dt*dc *dap*dap)-3'
  • Chain 'S':
    Compound: 5'-d(*da*da*da*da*dg*dg*dc*da*dg*dap)-3'
  • Chain 'T':
    Compound: 5'-d(*da*dg*dg*da*dt*dc*dc*dt*da*dap)-3'
  • Heterogens: MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2vblA (A:)
mntkynkefllylagfvdgdgsiiaqiepnasykfkhrlkltfkvtqktqrrwfldklvd
eigvgyvrdegsvsnyilseikplrnfltqlqpflklkqkqanlvlkiteqlpsakespd
kflevctwvdqiaalndsktrkttsetvravld

    Sequence, based on observed residues (ATOM records): (download) 
    >2vblA (A:)
ntkynkefllylagfvdgdgsiiaqiepnasykfkhrlkltfkvtqktqrrwfldklvde
igvgyvrdegsvsnyilseikplrnfltqlqpflklkqkqanlvlkiteqlpsakespdk
flevctwvdqiaalndsktrkttsetvravld

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2vblB (B:)
mntkynkefllylagfvdadgsiiaqiapnqsskfkhrlkltfqvtqktqrrwfldklvd
eigvgyvrgsgsvsnyilseikplhnfltqlqpflklkqkqanlvlkiieqlpsakespd
kflevctwvdqiaalndsktrkttsetvravld

    Sequence, based on observed residues (ATOM records): (download) 
    >2vblB (B:)
ntkynkefllylagfvdadgsiiaqiapnqsskfkhrlkltfqvtqktqrrwfldklvde
igvgyvrgsgsvsnyilseikplhnfltqlqpflklkqkqanlvlkiieqlpsakespdk
flevctwvdqiaalndsktrkttsetvravld

  • Chain 'C':
    No sequence available.

  • Chain 'E':
    No sequence available.

  • Chain 'S':
    No sequence available.

  • Chain 'T':
    No sequence available.