PDB entry 2vbj

View 2vbj on RCSB PDB site
Description: Molecular basis of human XPC gene recognition and cleavage by engineered homing endonuclease heterodimers
Class: hydrolase/DNA
Keywords: double strand break (dsb), cutting DNA endonucleases, amel3-4-calcium, uv-induced DNA damage, homing endonucleases (hes), hydrolase-DNA complex
Deposited on 2007-09-14, released 2008-10-28
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-05-29, with a file datestamp of 2019-05-24.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: N/A
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: DNA endonuclease I-crei
  Species: Chlamydomonas reinhardtii [TaxId:3055]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P05725 (0-151)
    • conflict (26)
    • conflict (36)
    • conflict (38)
    • conflict (40)
    • conflict (42)
    • conflict (68)
    • conflict (73)
    • conflict (83)
    • conflict (107-109)
  Domains in SCOPe 2.08: d2vbja_
• Chain 'B':
  Compound: DNA endonuclease I-crei
  Species: Chlamydomonas reinhardtii [TaxId:3055]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P05725 (0-151)
    • conflict (17)
    • conflict (26)
    • conflict (31)
    • conflict (36)
    • conflict (38)
    • conflict (40)
    • conflict (68)
    • conflict (73)
    • conflict (108-109)
  Domains in SCOPe 2.08: d2vbjb_
• Chain 'C':
  Compound: 5'-d(*tp*cp*tp*gp*cp*cp*tp*tp*tp*tp *tp*tp*gp*ap*ap*gp*gp*ap*tp*cp*cp*tp*ap*a)-3'
  Species: synthetic construct, synthetic [TaxId:32630]
  
• Chain 'E':
  Compound: 5'-d(*tp*tp*ap*gp*gp*ap*tp*cp*cp*tp *tp*cp*ap*ap*ap*ap*ap*ap*gp*gp*cp*ap*gp*a)-3'
  Species: synthetic construct, synthetic [TaxId:32630]
  
• Heterogens: CA, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2vbjA (A:)
  ntkynkefllylagfvdgdgsiiaqiepnqsykfkhrlkltfkvtqktqrrwfldklvde
  igvgyvrdegsvsnyilseikplrnfltqlqpflklkqkqanlvlkiteqlpsakespdk
  flevctwvdqiaalndsktrkttsetvravld
  

  
  
• Chain 'B':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2vbjB (B:)
  ntkynkefllylagfvdadgsiiaqiepnqsskfkhrlkltfqvtqktqrrwfldklvde
  igvgyvrdsgsvsnyilseikplhnfltqlqpflklkqkqanlvlkiieqlpsakespdk
  flevctwvdqiaalndsktrkttsetvravld
  

  
  
• Chain 'C':
  No sequence available.
  
  
• Chain 'E':
  No sequence available.