PDB entry 2vba

View 2vba on RCSB PDB site
Description: beta-ketoacyl-ACP synthase I (KAS) from E. coli with bound amino- thiazole inhibitor
Class: transferase
Keywords: cytoplasm, antibiotic, transferase, amino-thiazole, acyltransferase, lipid synthesis, fatty acid synthesis, fatty acid biosynthesis
Deposited on 2007-09-06, released 2007-12-25
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-05-08, with a file datestamp of 2019-05-03.
Experiment type: XRAY
Resolution: 1.36 Å
R-factor: N/A
AEROSPACI score: 0.55 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 3-oxoacyl-[acyl-carrier-protein] synthase 1
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2vbaa1, d2vbaa2
  • Chain 'B':
    Compound: 3-oxoacyl-[acyl-carrier-protein] synthase 1
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2vbab1, d2vbab2
  • Chain 'C':
    Compound: 3-oxoacyl-[acyl-carrier-protein] synthase 1
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2vbac1, d2vbac2
  • Chain 'D':
    Compound: 3-oxoacyl-[acyl-carrier-protein] synthase 1
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2vbad1, d2vbad2
  • Heterogens: P4T, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2vbaA (A:)
mkravitglgivssignnqqevlaslregrsgitfsqelkdsgmrshvwgnvkldttgli
drkvvrfmsdasiyaflsmeqaiadaglspeayqnnprvgliagsgggsprfqvfgadam
rgprglkavgpyvvtkamasgvsaclatpfkihgvnysissacatsahcignaveqiqlg
kqdivfagggeelcwemacefdamgalstkyndtpekasrtydahrdgfviaggggmvvv
eelehalargahiyaeivgygatsdgadmvapsgegavrcmkmamhgvdtpidylnshgt
stpvgdvkelaairevfgdkspaisatkamtghslgaagvqeaiysllmlehgfiapsin
ieeldeqaaglnivtettdrelttvmsnsfgfggtnatlvmrklkd

    Sequence, based on observed residues (ATOM records): (download) 
    >2vbaA (A:)
mkravitglgivssignnqqevlaslregrsgitfsqelkdsgmrshvwgnvkldttgli
drkvvrfmsdasiyaflsmeqaiadaglspeayqnnprvgliagsgggsprfqvfgadam
rgprglkavgpyvvtkamasgvsaclatpfkihgvnysissacatsahcignaveqiqlg
kqdivfagggeelcwemacefdamgalstkyndtpekasrtydahrdgfviaggggmvvv
eelehalargahiyaeivgygatsdgadmvapsgegavrcmkmamhgvdtpidylnshgt
stpvgdvkelaairevfgdkspaisatkamtghslgaagvqeaiysllmlehgfiapsin
ieeldeqaaglnivtettdrelttvmsnsfgfggtnatlvmrkl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2vbaB (B:)
mkravitglgivssignnqqevlaslregrsgitfsqelkdsgmrshvwgnvkldttgli
drkvvrfmsdasiyaflsmeqaiadaglspeayqnnprvgliagsgggsprfqvfgadam
rgprglkavgpyvvtkamasgvsaclatpfkihgvnysissacatsahcignaveqiqlg
kqdivfagggeelcwemacefdamgalstkyndtpekasrtydahrdgfviaggggmvvv
eelehalargahiyaeivgygatsdgadmvapsgegavrcmkmamhgvdtpidylnshgt
stpvgdvkelaairevfgdkspaisatkamtghslgaagvqeaiysllmlehgfiapsin
ieeldeqaaglnivtettdrelttvmsnsfgfggtnatlvmrklkd

    Sequence, based on observed residues (ATOM records): (download) 
    >2vbaB (B:)
mkravitglgivssignnqqevlaslregrsgitfsqelkdsgmrshvwgnvkldttgli
drkvvrfmsdasiyaflsmeqaiadaglspeayqnnprvgliagsgggsprfqvfgadam
rgprglkavgpyvvtkamasgvsaclatpfkihgvnysissacatsahcignaveqiqlg
kqdivfagggeelcwemacefdamgalstkyndtpekasrtydahrdgfviaggggmvvv
eelehalargahiyaeivgygatsdgadmvapsgegavrcmkmamhgvdtpidylnshgt
stpvgdvkelaairevfgdkspaisatkamtghslgaagvqeaiysllmlehgfiapsin
ieeldeqaaglnivtettdrelttvmsnsfgfggtnatlvmrkl

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2vbaC (C:)
mkravitglgivssignnqqevlaslregrsgitfsqelkdsgmrshvwgnvkldttgli
drkvvrfmsdasiyaflsmeqaiadaglspeayqnnprvgliagsgggsprfqvfgadam
rgprglkavgpyvvtkamasgvsaclatpfkihgvnysissacatsahcignaveqiqlg
kqdivfagggeelcwemacefdamgalstkyndtpekasrtydahrdgfviaggggmvvv
eelehalargahiyaeivgygatsdgadmvapsgegavrcmkmamhgvdtpidylnshgt
stpvgdvkelaairevfgdkspaisatkamtghslgaagvqeaiysllmlehgfiapsin
ieeldeqaaglnivtettdrelttvmsnsfgfggtnatlvmrklkd

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2vbaD (D:)
mkravitglgivssignnqqevlaslregrsgitfsqelkdsgmrshvwgnvkldttgli
drkvvrfmsdasiyaflsmeqaiadaglspeayqnnprvgliagsgggsprfqvfgadam
rgprglkavgpyvvtkamasgvsaclatpfkihgvnysissacatsahcignaveqiqlg
kqdivfagggeelcwemacefdamgalstkyndtpekasrtydahrdgfviaggggmvvv
eelehalargahiyaeivgygatsdgadmvapsgegavrcmkmamhgvdtpidylnshgt
stpvgdvkelaairevfgdkspaisatkamtghslgaagvqeaiysllmlehgfiapsin
ieeldeqaaglnivtettdrelttvmsnsfgfggtnatlvmrklkd

    Sequence, based on observed residues (ATOM records): (download) 
    >2vbaD (D:)
mkravitglgivssignnqqevlaslregrsgitfsqelkdsgmrshvwgnvkldttgli
drkvvrfmsdasiyaflsmeqaiadaglspeayqnnprvgliagsgggsprfqvfgadam
rgprglkavgpyvvtkamasgvsaclatpfkihgvnysissacatsahcignaveqiqlg
kqdivfagggeelcwemacefdamgalstkyndtpekasrtydahrdgfviaggggmvvv
eelehalargahiyaeivgygatsdgadmvapsgegavrcmkmamhgvdtpidylnshgt
stpvgdvkelaairevfgdkspaisatkamtghslgaagvqeaiysllmlehgfiapsin
ieeldeqaaglnivtettdrelttvmsnsfgfggtnatlvmrkl