PDB entry 2vb8

View 2vb8 on RCSB PDB site
Description: beta-ketoacyl-acp synthase I (kas) from e. coli with bound inhibitor thiolactomycin
Class: transferase
Keywords: cytoplasm, antibiotic, transferase, thiolactomycin, acyltransferase, lipid synthesis, fatty acid synthesis, fatty acid biosynthesis
Deposited on 2007-09-06, released 2007-12-25
The last revision prior to the SCOP 1.75 freeze date was dated 2007-12-25, with a file datestamp of 2007-12-21.
Experiment type: XRAY
Resolution: 1.52 Å
R-factor: 0.1528
AEROSPACI score: 0.76 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 3-oxoacyl-[acyl-carrier-protein] synthase 1
    Species: ESCHERICHIA COLI
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2vb8a1, d2vb8a2
  • Chain 'B':
    Compound: 3-oxoacyl-[acyl-carrier-protein] synthase 1
    Species: ESCHERICHIA COLI
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2vb8b1, d2vb8b2
  • Chain 'C':
    Compound: 3-oxoacyl-[acyl-carrier-protein] synthase 1
    Species: ESCHERICHIA COLI
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2vb8c1, d2vb8c2
  • Chain 'D':
    Compound: 3-oxoacyl-[acyl-carrier-protein] synthase 1
    Species: ESCHERICHIA COLI
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2vb8d1, d2vb8d2
  • Heterogens: CL, TLM, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2vb8A (A:)
mkravitglgivssignnqqevlaslregrsgitfsqelkdsgmrshvwgnvkldttgli
drkvvrfmsdasiyaflsmeqaiadaglspeayqnnprvgliagsgggsprfqvfgadam
rgprglkavgpyvvtkamasgvsaclatpfkihgvnysissacatsahcignaveqiqlg
kqdivfagggeelcwemacefdamgalstkyndtpekasrtydahrdgfviaggggmvvv
eelehalargahiyaeivgygatsdgadmvapsgegavrcmkmamhgvdtpidylnshgt
stpvgdvkelaairevfgdkspaisatkamtghslgaagvqeaiysllmlehgfiapsin
ieeldeqaaglnivtettdrelttvmsnsfgfggtnatlvmrklkd

    Sequence, based on observed residues (ATOM records): (download) 
    >2vb8A (A:)
mkravitglgivssignnqqevlaslregrsgitfsqelkdsgmrshvwgnvkldttgli
drkvvrfmsdasiyaflsmeqaiadaglspeayqnnprvgliagsgggsprfqvfgadam
rgprglkavgpyvvtkamasgvsaclatpfkihgvnysissacatsahcignaveqiqlg
kqdivfagggeelcwemacefdamgalstkyndtpekasrtydahrdgfviaggggmvvv
eelehalargahiyaeivgygatsdgadmvapsgegavrcmkmamhgvdtpidylnshgt
stpvgdvkelaairevfgdkspaisatkamtghslgaagvqeaiysllmlehgfiapsin
ieeldeqaaglnivtettdrelttvmsnsfgfggtnatlvmrkl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2vb8B (B:)
mkravitglgivssignnqqevlaslregrsgitfsqelkdsgmrshvwgnvkldttgli
drkvvrfmsdasiyaflsmeqaiadaglspeayqnnprvgliagsgggsprfqvfgadam
rgprglkavgpyvvtkamasgvsaclatpfkihgvnysissacatsahcignaveqiqlg
kqdivfagggeelcwemacefdamgalstkyndtpekasrtydahrdgfviaggggmvvv
eelehalargahiyaeivgygatsdgadmvapsgegavrcmkmamhgvdtpidylnshgt
stpvgdvkelaairevfgdkspaisatkamtghslgaagvqeaiysllmlehgfiapsin
ieeldeqaaglnivtettdrelttvmsnsfgfggtnatlvmrklkd

    Sequence, based on observed residues (ATOM records): (download) 
    >2vb8B (B:)
mkravitglgivssignnqqevlaslregrsgitfsqelkdsgmrshvwgnvkldttgli
drkvvrfmsdasiyaflsmeqaiadaglspeayqnnprvgliagsgggsprfqvfgadam
rgprglkavgpyvvtkamasgvsaclatpfkihgvnysissacatsahcignaveqiqlg
kqdivfagggeelcwemacefdamgalstkyndtpekasrtydahrdgfviaggggmvvv
eelehalargahiyaeivgygatsdgadmvapsgegavrcmkmamhgvdtpidylnshgt
stpvgdvkelaairevfgdkspaisatkamtghslgaagvqeaiysllmlehgfiapsin
ieeldeqaaglnivtettdrelttvmsnsfgfggtnatlvmrkl

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2vb8C (C:)
mkravitglgivssignnqqevlaslregrsgitfsqelkdsgmrshvwgnvkldttgli
drkvvrfmsdasiyaflsmeqaiadaglspeayqnnprvgliagsgggsprfqvfgadam
rgprglkavgpyvvtkamasgvsaclatpfkihgvnysissacatsahcignaveqiqlg
kqdivfagggeelcwemacefdamgalstkyndtpekasrtydahrdgfviaggggmvvv
eelehalargahiyaeivgygatsdgadmvapsgegavrcmkmamhgvdtpidylnshgt
stpvgdvkelaairevfgdkspaisatkamtghslgaagvqeaiysllmlehgfiapsin
ieeldeqaaglnivtettdrelttvmsnsfgfggtnatlvmrklkd

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2vb8D (D:)
mkravitglgivssignnqqevlaslregrsgitfsqelkdsgmrshvwgnvkldttgli
drkvvrfmsdasiyaflsmeqaiadaglspeayqnnprvgliagsgggsprfqvfgadam
rgprglkavgpyvvtkamasgvsaclatpfkihgvnysissacatsahcignaveqiqlg
kqdivfagggeelcwemacefdamgalstkyndtpekasrtydahrdgfviaggggmvvv
eelehalargahiyaeivgygatsdgadmvapsgegavrcmkmamhgvdtpidylnshgt
stpvgdvkelaairevfgdkspaisatkamtghslgaagvqeaiysllmlehgfiapsin
ieeldeqaaglnivtettdrelttvmsnsfgfggtnatlvmrklkd

    Sequence, based on observed residues (ATOM records): (download) 
    >2vb8D (D:)
mkravitglgivssignnqqevlaslregrsgitfsqelkdsgmrshvwgnvkldttgli
drkvvrfmsdasiyaflsmeqaiadaglspeayqnnprvgliagsgggsprfqvfgadam
rgprglkavgpyvvtkamasgvsaclatpfkihgvnysissacatsahcignaveqiqlg
kqdivfagggeelcwemacefdamgalstkyndtpekasrtydahrdgfviaggggmvvv
eelehalargahiyaeivgygatsdgadmvapsgegavrcmkmamhgvdtpidylnshgt
stpvgdvkelaairevfgdkspaisatkamtghslgaagvqeaiysllmlehgfiapsin
ieeldeqaaglnivtettdrelttvmsnsfgfggtnatlvmrkl