PDB entry 2vax

View 2vax on RCSB PDB site
Description: crystal structure of deacetylcephalosporin c acetyltransferase (cephalosporin c-soak)
Class: transferase
Keywords: deacetylcephalosporin c, cephalosporin biosynthesis, a/b-hydrolase fold, antibiotic biosynthesis, transferase, acyltransferase, acetyl transferase
Deposited on 2007-09-04, released 2008-09-23
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.212
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: acetyl-coa--deacetylcephalosporin c acetyltransferase
    Species: ACREMONIUM CHRYSOGENUM [TaxId:5044]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2vaxa_
  • Chain 'B':
    Compound: acetyl-coa--deacetylcephalosporin c acetyltransferase
    Species: ACREMONIUM CHRYSOGENUM [TaxId:5044]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2vaxb_
  • Chain 'C':
    Compound: acetyl-coa--deacetylcephalosporin c acetyltransferase
    Species: ACREMONIUM CHRYSOGENUM [TaxId:5044]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2vaxc_
  • Chain 'D':
    Compound: acetyl-coa--deacetylcephalosporin c acetyltransferase
    Species: ACREMONIUM CHRYSOGENUM [TaxId:5044]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2vaxd_
  • Chain 'E':
    Compound: acetyl-coa--deacetylcephalosporin c acetyltransferase
    Species: ACREMONIUM CHRYSOGENUM [TaxId:5044]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2vaxe_
  • Chain 'F':
    Compound: acetyl-coa--deacetylcephalosporin c acetyltransferase
    Species: ACREMONIUM CHRYSOGENUM [TaxId:5044]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2vaxf_
  • Chain 'G':
    Compound: acetyl-coa--deacetylcephalosporin c acetyltransferase
    Species: ACREMONIUM CHRYSOGENUM [TaxId:5044]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2vaxg_
  • Chain 'H':
    Compound: acetyl-coa--deacetylcephalosporin c acetyltransferase
    Species: ACREMONIUM CHRYSOGENUM [TaxId:5044]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2vaxh_
  • Chain 'I':
    Compound: acetyl-coa--deacetylcephalosporin c acetyltransferase
    Species: ACREMONIUM CHRYSOGENUM [TaxId:5044]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2vaxi_
  • Chain 'J':
    Compound: acetyl-coa--deacetylcephalosporin c acetyltransferase
    Species: ACREMONIUM CHRYSOGENUM [TaxId:5044]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2vaxj_
  • Chain 'K':
    Compound: acetyl-coa--deacetylcephalosporin c acetyltransferase
    Species: ACREMONIUM CHRYSOGENUM [TaxId:5044]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2vaxk_
  • Chain 'L':
    Compound: acetyl-coa--deacetylcephalosporin c acetyltransferase
    Species: ACREMONIUM CHRYSOGENUM [TaxId:5044]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2vaxl_
  • Heterogens: CSC, ACT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2vaxA (A:)
mlpsaqvarlkpdpfppslspiphgavtfaalapchnlpifssrqmlrdsltyshtsptm
spqianrfeasldaqdiarislftlesgvilrdvpvaykswgrmnvsrdncvivchtlts
sahvtswwptlfgqgrafdtsryfiiclnylgspfgsagpcspdpdaegqrpygakfprt
tirddvrihrqvldrlgvrqiaavvgasmggmhtlewaffgpeyvrkivpiatscrqsgw
caawfetqrqciyddpkyldgeydvddqpvrgletarkianltykskpamderfhmapgv
qagrnissqdakkeingtdsgnshragqpieavssylryqaqkfaasfdancyiamtlkf
dthdisrgragsipealamitqpaliicarsdglysfdehvemgrsipnsrlcvvdtneg
hdffvmeadkvndavrgfldqslm

    Sequence, based on observed residues (ATOM records): (download) 
    >2vaxA (A:)
nrfeasldaqdiarislftlesgvilrdvpvaykswgrmnvsrdncvivchtltssahvt
swwptlfgqgrafdtsryfiiclnylgspfgsagpcspdpdarpygakfprttirddvri
hrqvldrlgvrqiaavvgasmggmhtlewaffgpeyvrkivpiatscrqsgwcaawfetq
rqciyddpkyldgeydvddqpvrgletarkianltykskpamderfhmapgvgqpieavs
sylryqaqkfaasfdancyiamtlkfdthdisrgragsipealamitqpaliicarsdgl
ysfdehvemgrsipnsrlcvvdtneghdffvmeadkvndavrgfldq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2vaxB (B:)
mlpsaqvarlkpdpfppslspiphgavtfaalapchnlpifssrqmlrdsltyshtsptm
spqianrfeasldaqdiarislftlesgvilrdvpvaykswgrmnvsrdncvivchtlts
sahvtswwptlfgqgrafdtsryfiiclnylgspfgsagpcspdpdaegqrpygakfprt
tirddvrihrqvldrlgvrqiaavvgasmggmhtlewaffgpeyvrkivpiatscrqsgw
caawfetqrqciyddpkyldgeydvddqpvrgletarkianltykskpamderfhmapgv
qagrnissqdakkeingtdsgnshragqpieavssylryqaqkfaasfdancyiamtlkf
dthdisrgragsipealamitqpaliicarsdglysfdehvemgrsipnsrlcvvdtneg
hdffvmeadkvndavrgfldqslm

    Sequence, based on observed residues (ATOM records): (download) 
    >2vaxB (B:)
anrfeasldaqdiarislftlesgvilrdvpvaykswgrmnvsrdncvivchtltssahv
tswwptlfgqgrafdtsryfiiclnylgspfgsagpcspdpdarpygakfprttirddvr
ihrqvldrlgvrqiaavvgasmggmhtlewaffgpeyvrkivpiatscrqsgwcaawfet
qrqciyddpkyldgeydvddqpvrgletarkianltykskpamderfhmapgvgqpieav
ssylryqaqkfaasfdancyiamtlkfdthdisrgragsipealamitqpaliicarsdg
lysfdehvemgrsipnsrlcvvdtneghdffvmeadkvndavrgfldqs

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2vaxC (C:)
mlpsaqvarlkpdpfppslspiphgavtfaalapchnlpifssrqmlrdsltyshtsptm
spqianrfeasldaqdiarislftlesgvilrdvpvaykswgrmnvsrdncvivchtlts
sahvtswwptlfgqgrafdtsryfiiclnylgspfgsagpcspdpdaegqrpygakfprt
tirddvrihrqvldrlgvrqiaavvgasmggmhtlewaffgpeyvrkivpiatscrqsgw
caawfetqrqciyddpkyldgeydvddqpvrgletarkianltykskpamderfhmapgv
qagrnissqdakkeingtdsgnshragqpieavssylryqaqkfaasfdancyiamtlkf
dthdisrgragsipealamitqpaliicarsdglysfdehvemgrsipnsrlcvvdtneg
hdffvmeadkvndavrgfldqslm

    Sequence, based on observed residues (ATOM records): (download) 
    >2vaxC (C:)
qianrfeasldaqdiarislftlesgvilrdvpvaykswgrmnvsrdncvivchtltssa
hvtswwptlfgqgrafdtsryfiiclnylgspfgsagpcspdpdaegqrpygakfprtti
rddvrihrqvldrlgvrqiaavvgasmggmhtlewaffgpeyvrkivpiatscrqsgwca
awfetqrqciyddpkyldgeydvddqpvrgletarkianltykskpamderfhmqpieav
ssylryqaqkfaasfdancyiamtlkfdthdisrgragsipealamitqpaliicarsdg
lysfdehvemgrsipnsrlcvvdtneghdffvmeadkvndavrgfldq

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2vaxD (D:)
mlpsaqvarlkpdpfppslspiphgavtfaalapchnlpifssrqmlrdsltyshtsptm
spqianrfeasldaqdiarislftlesgvilrdvpvaykswgrmnvsrdncvivchtlts
sahvtswwptlfgqgrafdtsryfiiclnylgspfgsagpcspdpdaegqrpygakfprt
tirddvrihrqvldrlgvrqiaavvgasmggmhtlewaffgpeyvrkivpiatscrqsgw
caawfetqrqciyddpkyldgeydvddqpvrgletarkianltykskpamderfhmapgv
qagrnissqdakkeingtdsgnshragqpieavssylryqaqkfaasfdancyiamtlkf
dthdisrgragsipealamitqpaliicarsdglysfdehvemgrsipnsrlcvvdtneg
hdffvmeadkvndavrgfldqslm

    Sequence, based on observed residues (ATOM records): (download) 
    >2vaxD (D:)
ianrfeasldaqdiarislftlesgvilrdvpvaykswgrmnvsrdncvivchtltssah
vtswwptlfgqgrafdtsryfiiclnylgspfgsagpcspdpdaqrpygakfprttirdd
vrihrqvldrlgvrqiaavvgasmggmhtlewaffgpeyvrkivpiatscrqsgwcaawf
etqrqciyddpkyldgeydvddqpvrgletarkianltykskpamderfhmqpieavssy
lryqaqkfaasfdancyiamtlkfdthdisrgragsipealamitqpaliicarsdglys
fdehvemgrsipnsrlcvvdtneghdffvmeadkvndavrgfldq

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2vaxE (E:)
mlpsaqvarlkpdpfppslspiphgavtfaalapchnlpifssrqmlrdsltyshtsptm
spqianrfeasldaqdiarislftlesgvilrdvpvaykswgrmnvsrdncvivchtlts
sahvtswwptlfgqgrafdtsryfiiclnylgspfgsagpcspdpdaegqrpygakfprt
tirddvrihrqvldrlgvrqiaavvgasmggmhtlewaffgpeyvrkivpiatscrqsgw
caawfetqrqciyddpkyldgeydvddqpvrgletarkianltykskpamderfhmapgv
qagrnissqdakkeingtdsgnshragqpieavssylryqaqkfaasfdancyiamtlkf
dthdisrgragsipealamitqpaliicarsdglysfdehvemgrsipnsrlcvvdtneg
hdffvmeadkvndavrgfldqslm

    Sequence, based on observed residues (ATOM records): (download) 
    >2vaxE (E:)
nrfeasldaqdiarislftlesgvilrdvpvaykswgrmnvsrdncvivchtltssahvt
swwptlfgqgrafdtsryfiiclnylgspfgsagpcspdpdapygakfprttirddvrih
rqvldrlgvrqiaavvgasmggmhtlewaffgpeyvrkivpiatscrqsgwcaawfetqr
qciyddpkyldgeydvddqpvrgletarkianltykskpamderfhmapgvgqpieavss
ylryqaqkfaasfdancyiamtlkfdthdisrgragsipealamitqpaliicarsdgly
sfdehvemgrsipnsrlcvvdtneghdffvmeadkvndavrgfldq

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >2vaxF (F:)
mlpsaqvarlkpdpfppslspiphgavtfaalapchnlpifssrqmlrdsltyshtsptm
spqianrfeasldaqdiarislftlesgvilrdvpvaykswgrmnvsrdncvivchtlts
sahvtswwptlfgqgrafdtsryfiiclnylgspfgsagpcspdpdaegqrpygakfprt
tirddvrihrqvldrlgvrqiaavvgasmggmhtlewaffgpeyvrkivpiatscrqsgw
caawfetqrqciyddpkyldgeydvddqpvrgletarkianltykskpamderfhmapgv
qagrnissqdakkeingtdsgnshragqpieavssylryqaqkfaasfdancyiamtlkf
dthdisrgragsipealamitqpaliicarsdglysfdehvemgrsipnsrlcvvdtneg
hdffvmeadkvndavrgfldqslm

    Sequence, based on observed residues (ATOM records): (download) 
    >2vaxF (F:)
nrfeasldaqdiarislftlesgvilrdvpvaykswgrmnvsrdncvivchtltssahvt
swwptlfgqgrafdtsryfiiclnylgspfgsagpcspdpdapygakfprttirddvrih
rqvldrlgvrqiaavvgasmggmhtlewaffgpeyvrkivpiatscrqsgwcaawfetqr
qciyddpkyldgeydvddqpvrgletarkianltykskpamderfhmqpieavssylryq
aqkfaasfdancyiamtlkfdthdisrgragsipealamitqpaliicarsdglysfdeh
vemgrsipnsrlcvvdtneghdffvmeadkvndavrgfldqs

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >2vaxG (G:)
mlpsaqvarlkpdpfppslspiphgavtfaalapchnlpifssrqmlrdsltyshtsptm
spqianrfeasldaqdiarislftlesgvilrdvpvaykswgrmnvsrdncvivchtlts
sahvtswwptlfgqgrafdtsryfiiclnylgspfgsagpcspdpdaegqrpygakfprt
tirddvrihrqvldrlgvrqiaavvgasmggmhtlewaffgpeyvrkivpiatscrqsgw
caawfetqrqciyddpkyldgeydvddqpvrgletarkianltykskpamderfhmapgv
qagrnissqdakkeingtdsgnshragqpieavssylryqaqkfaasfdancyiamtlkf
dthdisrgragsipealamitqpaliicarsdglysfdehvemgrsipnsrlcvvdtneg
hdffvmeadkvndavrgfldqslm

    Sequence, based on observed residues (ATOM records): (download) 
    >2vaxG (G:)
nrfeasldaqdiarislftlesgvilrdvpvaykswgrmnvsrdncvivchtltssahvt
swwptlfgqgrafdtsryfiiclnylgspfgsagpcspdpdarpygakfprttirddvri
hrqvldrlgvrqiaavvgasmggmhtlewaffgpeyvrkivpiatscrqsgwcaawfetq
rqciyddpkyldgeydvddqpvrgletarkianltykskpamderfhmqpieavssylry
qaqkfaasfdancyiamtlkfdthdisrgragsipealamitqpaliicarsdglysfde
hvemgrsipnsrlcvvdtneghdffvmeadkvndavrgfldq

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >2vaxH (H:)
mlpsaqvarlkpdpfppslspiphgavtfaalapchnlpifssrqmlrdsltyshtsptm
spqianrfeasldaqdiarislftlesgvilrdvpvaykswgrmnvsrdncvivchtlts
sahvtswwptlfgqgrafdtsryfiiclnylgspfgsagpcspdpdaegqrpygakfprt
tirddvrihrqvldrlgvrqiaavvgasmggmhtlewaffgpeyvrkivpiatscrqsgw
caawfetqrqciyddpkyldgeydvddqpvrgletarkianltykskpamderfhmapgv
qagrnissqdakkeingtdsgnshragqpieavssylryqaqkfaasfdancyiamtlkf
dthdisrgragsipealamitqpaliicarsdglysfdehvemgrsipnsrlcvvdtneg
hdffvmeadkvndavrgfldqslm

    Sequence, based on observed residues (ATOM records): (download) 
    >2vaxH (H:)
nrfeasldaqdiarislftlesgvilrdvpvaykswgrmnvsrdncvivchtltssahvt
swwptlfgqgrafdtsryfiiclnylgspfgsagpcspdpdarpygakfprttirddvri
hrqvldrlgvrqiaavvgasmggmhtlewaffgpeyvrkivpiatscrqsgwcaawfetq
rqciyddpkyldgeydvddqpvrgletarkianltykskpamderfhmqpieavssylry
qaqkfaasfdancyiamtlkfdthdisrgragsipealamitqpaliicarsdglysfde
hvemgrsipnsrlcvvdtneghdffvmeadkvndavrgfldq

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >2vaxI (I:)
mlpsaqvarlkpdpfppslspiphgavtfaalapchnlpifssrqmlrdsltyshtsptm
spqianrfeasldaqdiarislftlesgvilrdvpvaykswgrmnvsrdncvivchtlts
sahvtswwptlfgqgrafdtsryfiiclnylgspfgsagpcspdpdaegqrpygakfprt
tirddvrihrqvldrlgvrqiaavvgasmggmhtlewaffgpeyvrkivpiatscrqsgw
caawfetqrqciyddpkyldgeydvddqpvrgletarkianltykskpamderfhmapgv
qagrnissqdakkeingtdsgnshragqpieavssylryqaqkfaasfdancyiamtlkf
dthdisrgragsipealamitqpaliicarsdglysfdehvemgrsipnsrlcvvdtneg
hdffvmeadkvndavrgfldqslm

    Sequence, based on observed residues (ATOM records): (download) 
    >2vaxI (I:)
anrfeasldaqdiarislftlesgvilrdvpvaykswgrmnvsrdncvivchtltssahv
tswwptlfgqgrafdtsryfiiclnylgspfgsagpcspdpdarpygakfprttirddvr
ihrqvldrlgvrqiaavvgasmggmhtlewaffgpeyvrkivpiatscrqsgwcaawfet
qrqciyddpkyldgeydvddqpvrgletarkianltykskpamderfhmapgvgqpieav
ssylryqaqkfaasfdancyiamtlkfdthdisrgragsipealamitqpaliicarsdg
lysfdehvemgrsipnsrlcvvdtneghdffvmeadkvndavrgfldqs

  • Chain 'J':
    Sequence, based on SEQRES records: (download) 
    >2vaxJ (J:)
mlpsaqvarlkpdpfppslspiphgavtfaalapchnlpifssrqmlrdsltyshtsptm
spqianrfeasldaqdiarislftlesgvilrdvpvaykswgrmnvsrdncvivchtlts
sahvtswwptlfgqgrafdtsryfiiclnylgspfgsagpcspdpdaegqrpygakfprt
tirddvrihrqvldrlgvrqiaavvgasmggmhtlewaffgpeyvrkivpiatscrqsgw
caawfetqrqciyddpkyldgeydvddqpvrgletarkianltykskpamderfhmapgv
qagrnissqdakkeingtdsgnshragqpieavssylryqaqkfaasfdancyiamtlkf
dthdisrgragsipealamitqpaliicarsdglysfdehvemgrsipnsrlcvvdtneg
hdffvmeadkvndavrgfldqslm

    Sequence, based on observed residues (ATOM records): (download) 
    >2vaxJ (J:)
nrfeasldaqdiarislftlesgvilrdvpvaykswgrmnvsrdncvivchtltssahvt
swwptlfgqgrafdtsryfiiclnylgspfgsagpcspdpdapygakfprttirddvrih
rqvldrlgvrqiaavvgasmggmhtlewaffgpeyvrkivpiatscrqsgwcaawfetqr
qciyddpkyldgeydvddqpvrgletarkianltykskpamderfhmgqpieavssylry
qaqkfaasfdancyiamtlkfdthdisrgragsipealamitqpaliicarsdglysfde
hvemgrsipnsrlcvvdtneghdffvmeadkvndavrgfldqsl

  • Chain 'K':
    Sequence, based on SEQRES records: (download) 
    >2vaxK (K:)
mlpsaqvarlkpdpfppslspiphgavtfaalapchnlpifssrqmlrdsltyshtsptm
spqianrfeasldaqdiarislftlesgvilrdvpvaykswgrmnvsrdncvivchtlts
sahvtswwptlfgqgrafdtsryfiiclnylgspfgsagpcspdpdaegqrpygakfprt
tirddvrihrqvldrlgvrqiaavvgasmggmhtlewaffgpeyvrkivpiatscrqsgw
caawfetqrqciyddpkyldgeydvddqpvrgletarkianltykskpamderfhmapgv
qagrnissqdakkeingtdsgnshragqpieavssylryqaqkfaasfdancyiamtlkf
dthdisrgragsipealamitqpaliicarsdglysfdehvemgrsipnsrlcvvdtneg
hdffvmeadkvndavrgfldqslm

    Sequence, based on observed residues (ATOM records): (download) 
    >2vaxK (K:)
nrfeasldaqdiarislftlesgvilrdvpvaykswgrmnvsrdncvivchtltssahvt
swwptlfgqgrafdtsryfiiclnylgspfgsagpcspdpdapygakfprttirddvrih
rqvldrlgvrqiaavvgasmggmhtlewaffgpeyvrkivpiatscrqsgwcaawfetqr
qciyddpkyldgeydvddqpvrgletarkianltykskpamderfhmgqpieavssylry
qaqkfaasfdancyiamtlkfdthdisrgragsipealamitqpaliicarsdglysfde
hvemgrsipnsrlcvvdtneghdffvmeadkvndavrgfldqsl

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >2vaxL (L:)
mlpsaqvarlkpdpfppslspiphgavtfaalapchnlpifssrqmlrdsltyshtsptm
spqianrfeasldaqdiarislftlesgvilrdvpvaykswgrmnvsrdncvivchtlts
sahvtswwptlfgqgrafdtsryfiiclnylgspfgsagpcspdpdaegqrpygakfprt
tirddvrihrqvldrlgvrqiaavvgasmggmhtlewaffgpeyvrkivpiatscrqsgw
caawfetqrqciyddpkyldgeydvddqpvrgletarkianltykskpamderfhmapgv
qagrnissqdakkeingtdsgnshragqpieavssylryqaqkfaasfdancyiamtlkf
dthdisrgragsipealamitqpaliicarsdglysfdehvemgrsipnsrlcvvdtneg
hdffvmeadkvndavrgfldqslm

    Sequence, based on observed residues (ATOM records): (download) 
    >2vaxL (L:)
nrfeasldaqdiarislftlesgvilrdvpvaykswgrmnvsrdncvivchtltssahvt
swwptlfgqgrafdtsryfiiclnylgspfgsagpcspdpdpygakfprttirddvrihr
qvldrlgvrqiaavvgasmggmhtlewaffgpeyvrkivpiatscrqsgwcaawfetqrq
ciyddpkyldgeydvddqpvrgletarkianltykskpamderfhmgqpieavssylryq
aqkfaasfdancyiamtlkfdthdisrgragsipealamitqpaliicarsdglysfdeh
vemgrsipnsrlcvvdtneghdffvmeadkvndavrgfldq