PDB entry 2vav

View 2vav on RCSB PDB site
Description: crystal structure of deacetylcephalosporin c acetyltransferase (dac-soak)
Class: transferase
Keywords: acetyl transferase, a/b- hydrolase fold, transferase, acyltransferase, acetyl coenzyme a, antibiotic biosynthesis, cephalosporin biosynthesis
Deposited on 2007-09-04, released 2008-09-23
The last revision prior to the SCOP 1.75 freeze date was dated 2008-09-23, with a file datestamp of 2008-09-19.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.21981
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: acetyl-coa--deacetylcephalosporin c acetyltransferase
    Species: ACREMONIUM CHRYSOGENUM
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2vava1
  • Chain 'B':
    Compound: acetyl-coa--deacetylcephalosporin c acetyltransferase
    Species: ACREMONIUM CHRYSOGENUM
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2vavb1
  • Chain 'C':
    Compound: acetyl-coa--deacetylcephalosporin c acetyltransferase
    Species: ACREMONIUM CHRYSOGENUM
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2vavc1
  • Chain 'D':
    Compound: acetyl-coa--deacetylcephalosporin c acetyltransferase
    Species: ACREMONIUM CHRYSOGENUM
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2vavd1
  • Chain 'E':
    Compound: acetyl-coa--deacetylcephalosporin c acetyltransferase
    Species: ACREMONIUM CHRYSOGENUM
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2vave1
  • Chain 'F':
    Compound: acetyl-coa--deacetylcephalosporin c acetyltransferase
    Species: ACREMONIUM CHRYSOGENUM
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2vavf1
  • Chain 'G':
    Compound: acetyl-coa--deacetylcephalosporin c acetyltransferase
    Species: ACREMONIUM CHRYSOGENUM
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2vavg1
  • Chain 'H':
    Compound: acetyl-coa--deacetylcephalosporin c acetyltransferase
    Species: ACREMONIUM CHRYSOGENUM
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2vavh1
  • Chain 'I':
    Compound: acetyl-coa--deacetylcephalosporin c acetyltransferase
    Species: ACREMONIUM CHRYSOGENUM
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2vavi1
  • Chain 'J':
    Compound: acetyl-coa--deacetylcephalosporin c acetyltransferase
    Species: ACREMONIUM CHRYSOGENUM
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2vavj1
  • Chain 'K':
    Compound: acetyl-coa--deacetylcephalosporin c acetyltransferase
    Species: ACREMONIUM CHRYSOGENUM
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2vavk1
  • Chain 'L':
    Compound: acetyl-coa--deacetylcephalosporin c acetyltransferase
    Species: ACREMONIUM CHRYSOGENUM
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2vavl1
  • Heterogens: CSC, ACT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2vavA (A:)
mlpsaqvarlkpdpfppslspiphgavtfaalapchnlpifssrqmlrdsltyshtsptm
spqianrfeasldaqdiarislftlesgvilrdvpvaykswgrmnvsrdncvivchtlts
sahvtswwptlfgqgrafdtsryfiiclnylgspfgsagpcspdpdaegqrpygakfprt
tirddvrihrqvldrlgvrqiaavvgasmggmhtlewaffgpeyvrkivpiatscrqsgw
caawfetqrqciyddpkyldgeydvddqpvrgletarkianltykskpamderfhmapgv
qagrnissqdakkeingtdsgnshragqpieavssylryqaqkfaasfdancyiamtlkf
dthdisrgragsipealamitqpaliicarsdglysfdehvemgrsipnsrlcvvdtneg
hdffvmeadkvndavrgfldqslm

    Sequence, based on observed residues (ATOM records): (download) 
    >2vavA (A:)
nrfeasldaqdiarislftlesgvilrdvpvaykswgrmnvsrdncvivchtltssahvt
swwptlfgqgrafdtsryfiiclnylgspfgsagpcspdpdaerpygakfprttirddvr
ihrqvldrlgvrqiaavvgasmggmhtlewaffgpeyvrkivpiatscrqsgwcaawfet
qrqciyddpkyldgeydvddqpvrgletarkianltykskpamderfhmapgvgqpieav
ssylryqaqkfaasfdancyiamtlkfdthdisrgragsipealamitqpaliicarsdg
lysfdehvemgrsipnsrlcvvdtneghdffvmeadkvndavrgfldq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2vavB (B:)
mlpsaqvarlkpdpfppslspiphgavtfaalapchnlpifssrqmlrdsltyshtsptm
spqianrfeasldaqdiarislftlesgvilrdvpvaykswgrmnvsrdncvivchtlts
sahvtswwptlfgqgrafdtsryfiiclnylgspfgsagpcspdpdaegqrpygakfprt
tirddvrihrqvldrlgvrqiaavvgasmggmhtlewaffgpeyvrkivpiatscrqsgw
caawfetqrqciyddpkyldgeydvddqpvrgletarkianltykskpamderfhmapgv
qagrnissqdakkeingtdsgnshragqpieavssylryqaqkfaasfdancyiamtlkf
dthdisrgragsipealamitqpaliicarsdglysfdehvemgrsipnsrlcvvdtneg
hdffvmeadkvndavrgfldqslm

    Sequence, based on observed residues (ATOM records): (download) 
    >2vavB (B:)
anrfeasldaqdiarislftlesgvilrdvpvaykswgrmnvsrdncvivchtltssahv
tswwptlfgqgrafdtsryfiiclnylgspfgsagpcspdpdaqrpygakfprttirddv
rihrqvldrlgvrqiaavvgasmggmhtlewaffgpeyvrkivpiatscrqsgwcaawfe
tqrqciyddpkyldgeydvddqpvrgletarkianltykskpamderfhmapgvgqpiea
vssylryqaqkfaasfdancyiamtlkfdthdisrgragsipealamitqpaliicarsd
glysfdehvemgrsipnsrlcvvdtneghdffvmeadkvndavrgfldqs

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2vavC (C:)
mlpsaqvarlkpdpfppslspiphgavtfaalapchnlpifssrqmlrdsltyshtsptm
spqianrfeasldaqdiarislftlesgvilrdvpvaykswgrmnvsrdncvivchtlts
sahvtswwptlfgqgrafdtsryfiiclnylgspfgsagpcspdpdaegqrpygakfprt
tirddvrihrqvldrlgvrqiaavvgasmggmhtlewaffgpeyvrkivpiatscrqsgw
caawfetqrqciyddpkyldgeydvddqpvrgletarkianltykskpamderfhmapgv
qagrnissqdakkeingtdsgnshragqpieavssylryqaqkfaasfdancyiamtlkf
dthdisrgragsipealamitqpaliicarsdglysfdehvemgrsipnsrlcvvdtneg
hdffvmeadkvndavrgfldqslm

    Sequence, based on observed residues (ATOM records): (download) 
    >2vavC (C:)
ianrfeasldaqdiarislftlesgvilrdvpvaykswgrmnvsrdncvivchtltssah
vtswwptlfgqgrafdtsryfiiclnylgspfgsagpcspdpdaegqrpygakfprttir
ddvrihrqvldrlgvrqiaavvgasmggmhtlewaffgpeyvrkivpiatscrqsgwcaa
wfetqrqciyddpkyldgeydvddqpvrgletarkianltykskpamderfhmqpieavs
sylryqaqkfaasfdancyiamtlkfdthdisrgragsipealamitqpaliicarsdgl
ysfdehvemgrsipnsrlcvvdtneghdffvmeadkvndavrgfldq

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2vavD (D:)
mlpsaqvarlkpdpfppslspiphgavtfaalapchnlpifssrqmlrdsltyshtsptm
spqianrfeasldaqdiarislftlesgvilrdvpvaykswgrmnvsrdncvivchtlts
sahvtswwptlfgqgrafdtsryfiiclnylgspfgsagpcspdpdaegqrpygakfprt
tirddvrihrqvldrlgvrqiaavvgasmggmhtlewaffgpeyvrkivpiatscrqsgw
caawfetqrqciyddpkyldgeydvddqpvrgletarkianltykskpamderfhmapgv
qagrnissqdakkeingtdsgnshragqpieavssylryqaqkfaasfdancyiamtlkf
dthdisrgragsipealamitqpaliicarsdglysfdehvemgrsipnsrlcvvdtneg
hdffvmeadkvndavrgfldqslm

    Sequence, based on observed residues (ATOM records): (download) 
    >2vavD (D:)
ianrfeasldaqdiarislftlesgvilrdvpvaykswgrmnvsrdncvivchtltssah
vtswwptlfgqgrafdtsryfiiclnylgspfgsagpcspdpdaqrpygakfprttirdd
vrihrqvldrlgvrqiaavvgasmggmhtlewaffgpeyvrkivpiatscrqsgwcaawf
etqrqciyddpkyldgeydvddqpvrgletarkianltykskpamderfhmqpieavssy
lryqaqkfaasfdancyiamtlkfdthdisrgragsipealamitqpaliicarsdglys
fdehvemgrsipnsrlcvvdtneghdffvmeadkvndavrgfldq

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2vavE (E:)
mlpsaqvarlkpdpfppslspiphgavtfaalapchnlpifssrqmlrdsltyshtsptm
spqianrfeasldaqdiarislftlesgvilrdvpvaykswgrmnvsrdncvivchtlts
sahvtswwptlfgqgrafdtsryfiiclnylgspfgsagpcspdpdaegqrpygakfprt
tirddvrihrqvldrlgvrqiaavvgasmggmhtlewaffgpeyvrkivpiatscrqsgw
caawfetqrqciyddpkyldgeydvddqpvrgletarkianltykskpamderfhmapgv
qagrnissqdakkeingtdsgnshragqpieavssylryqaqkfaasfdancyiamtlkf
dthdisrgragsipealamitqpaliicarsdglysfdehvemgrsipnsrlcvvdtneg
hdffvmeadkvndavrgfldqslm

    Sequence, based on observed residues (ATOM records): (download) 
    >2vavE (E:)
nrfeasldaqdiarislftlesgvilrdvpvaykswgrmnvsrdncvivchtltssahvt
swwptlfgqgrafdtsryfiiclnylgspfgsagpcspdpdapygakfprttirddvrih
rqvldrlgvrqiaavvgasmggmhtlewaffgpeyvrkivpiatscrqsgwcaawfetqr
qciyddpkyldgeydvddqpvrgletarkianltykskpamderfhmapgvgqpieavss
ylryqaqkfaasfdancyiamtlkfdthdisrgragsipealamitqpaliicarsdgly
sfdehvemgrsipnsrlcvvdtneghdffvmeadkvndavrgfldq

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >2vavF (F:)
mlpsaqvarlkpdpfppslspiphgavtfaalapchnlpifssrqmlrdsltyshtsptm
spqianrfeasldaqdiarislftlesgvilrdvpvaykswgrmnvsrdncvivchtlts
sahvtswwptlfgqgrafdtsryfiiclnylgspfgsagpcspdpdaegqrpygakfprt
tirddvrihrqvldrlgvrqiaavvgasmggmhtlewaffgpeyvrkivpiatscrqsgw
caawfetqrqciyddpkyldgeydvddqpvrgletarkianltykskpamderfhmapgv
qagrnissqdakkeingtdsgnshragqpieavssylryqaqkfaasfdancyiamtlkf
dthdisrgragsipealamitqpaliicarsdglysfdehvemgrsipnsrlcvvdtneg
hdffvmeadkvndavrgfldqslm

    Sequence, based on observed residues (ATOM records): (download) 
    >2vavF (F:)
nrfeasldaqdiarislftlesgvilrdvpvaykswgrmnvsrdncvivchtltssahvt
swwptlfgqgrafdtsryfiiclnylgspfgsagpcspdpdapygakfprttirddvrih
rqvldrlgvrqiaavvgasmggmhtlewaffgpeyvrkivpiatscrqsgwcaawfetqr
qciyddpkyldgeydvddqpvrgletarkianltykskpamderfhmqpieavssylryq
aqkfaasfdancyiamtlkfdthdisrgragsipealamitqpaliicarsdglysfdeh
vemgrsipnsrlcvvdtneghdffvmeadkvndavrgfldq

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >2vavG (G:)
mlpsaqvarlkpdpfppslspiphgavtfaalapchnlpifssrqmlrdsltyshtsptm
spqianrfeasldaqdiarislftlesgvilrdvpvaykswgrmnvsrdncvivchtlts
sahvtswwptlfgqgrafdtsryfiiclnylgspfgsagpcspdpdaegqrpygakfprt
tirddvrihrqvldrlgvrqiaavvgasmggmhtlewaffgpeyvrkivpiatscrqsgw
caawfetqrqciyddpkyldgeydvddqpvrgletarkianltykskpamderfhmapgv
qagrnissqdakkeingtdsgnshragqpieavssylryqaqkfaasfdancyiamtlkf
dthdisrgragsipealamitqpaliicarsdglysfdehvemgrsipnsrlcvvdtneg
hdffvmeadkvndavrgfldqslm

    Sequence, based on observed residues (ATOM records): (download) 
    >2vavG (G:)
nrfeasldaqdiarislftlesgvilrdvpvaykswgrmnvsrdncvivchtltssahvt
swwptlfgqgrafdtsryfiiclnylgspfgsagpcspdpdarpygakfprttirddvri
hrqvldrlgvrqiaavvgasmggmhtlewaffgpeyvrkivpiatscrqsgwcaawfetq
rqciyddpkyldgeydvddqpvrgletarkianltykskpamderfhmqpieavssylry
qaqkfaasfdancyiamtlkfdthdisrgragsipealamitqpaliicarsdglysfde
hvemgrsipnsrlcvvdtneghdffvmeadkvndavrgfldq

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >2vavH (H:)
mlpsaqvarlkpdpfppslspiphgavtfaalapchnlpifssrqmlrdsltyshtsptm
spqianrfeasldaqdiarislftlesgvilrdvpvaykswgrmnvsrdncvivchtlts
sahvtswwptlfgqgrafdtsryfiiclnylgspfgsagpcspdpdaegqrpygakfprt
tirddvrihrqvldrlgvrqiaavvgasmggmhtlewaffgpeyvrkivpiatscrqsgw
caawfetqrqciyddpkyldgeydvddqpvrgletarkianltykskpamderfhmapgv
qagrnissqdakkeingtdsgnshragqpieavssylryqaqkfaasfdancyiamtlkf
dthdisrgragsipealamitqpaliicarsdglysfdehvemgrsipnsrlcvvdtneg
hdffvmeadkvndavrgfldqslm

    Sequence, based on observed residues (ATOM records): (download) 
    >2vavH (H:)
nrfeasldaqdiarislftlesgvilrdvpvaykswgrmnvsrdncvivchtltssahvt
swwptlfgqgrafdtsryfiiclnylgspfgsagpcspdpdaerpygakfprttirddvr
ihrqvldrlgvrqiaavvgasmggmhtlewaffgpeyvrkivpiatscrqsgwcaawfet
qrqciyddpkyldgeydvddqpvrgletarkianltykskpamderfhmqpieavssylr
yqaqkfaasfdancyiamtlkfdthdisrgragsipealamitqpaliicarsdglysfd
ehvemgrsipnsrlcvvdtneghdffvmeadkvndavrgfldq

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >2vavI (I:)
mlpsaqvarlkpdpfppslspiphgavtfaalapchnlpifssrqmlrdsltyshtsptm
spqianrfeasldaqdiarislftlesgvilrdvpvaykswgrmnvsrdncvivchtlts
sahvtswwptlfgqgrafdtsryfiiclnylgspfgsagpcspdpdaegqrpygakfprt
tirddvrihrqvldrlgvrqiaavvgasmggmhtlewaffgpeyvrkivpiatscrqsgw
caawfetqrqciyddpkyldgeydvddqpvrgletarkianltykskpamderfhmapgv
qagrnissqdakkeingtdsgnshragqpieavssylryqaqkfaasfdancyiamtlkf
dthdisrgragsipealamitqpaliicarsdglysfdehvemgrsipnsrlcvvdtneg
hdffvmeadkvndavrgfldqslm

    Sequence, based on observed residues (ATOM records): (download) 
    >2vavI (I:)
nrfeasldaqdiarislftlesgvilrdvpvaykswgrmnvsrdncvivchtltssahvt
swwptlfgqgrafdtsryfiiclnylgspfgsagpcspdpdarpygakfprttirddvri
hrqvldrlgvrqiaavvgasmggmhtlewaffgpeyvrkivpiatscrqsgwcaawfetq
rqciyddpkyldgeydvddqpvrgletarkianltykskpamderfhmapgvgqpieavs
sylryqaqkfaasfdancyiamtlkfdthdisrgragsipealamitqpaliicarsdgl
ysfdehvemgrsipnsrlcvvdtneghdffvmeadkvndavrgfldqs

  • Chain 'J':
    Sequence, based on SEQRES records: (download) 
    >2vavJ (J:)
mlpsaqvarlkpdpfppslspiphgavtfaalapchnlpifssrqmlrdsltyshtsptm
spqianrfeasldaqdiarislftlesgvilrdvpvaykswgrmnvsrdncvivchtlts
sahvtswwptlfgqgrafdtsryfiiclnylgspfgsagpcspdpdaegqrpygakfprt
tirddvrihrqvldrlgvrqiaavvgasmggmhtlewaffgpeyvrkivpiatscrqsgw
caawfetqrqciyddpkyldgeydvddqpvrgletarkianltykskpamderfhmapgv
qagrnissqdakkeingtdsgnshragqpieavssylryqaqkfaasfdancyiamtlkf
dthdisrgragsipealamitqpaliicarsdglysfdehvemgrsipnsrlcvvdtneg
hdffvmeadkvndavrgfldqslm

    Sequence, based on observed residues (ATOM records): (download) 
    >2vavJ (J:)
nrfeasldaqdiarislftlesgvilrdvpvaykswgrmnvsrdncvivchtltssahvt
swwptlfgqgrafdtsryfiiclnylgspfgsagpcspdpdapygakfprttirddvrih
rqvldrlgvrqiaavvgasmggmhtlewaffgpeyvrkivpiatscrqsgwcaawfetqr
qciyddpkyldgeydvddqpvrgletarkianltykskpamderfhmgqpieavssylry
qaqkfaasfdancyiamtlkfdthdisrgragsipealamitqpaliicarsdglysfde
hvemgrsipnsrlcvvdtneghdffvmeadkvndavrgfldqsl

  • Chain 'K':
    Sequence, based on SEQRES records: (download) 
    >2vavK (K:)
mlpsaqvarlkpdpfppslspiphgavtfaalapchnlpifssrqmlrdsltyshtsptm
spqianrfeasldaqdiarislftlesgvilrdvpvaykswgrmnvsrdncvivchtlts
sahvtswwptlfgqgrafdtsryfiiclnylgspfgsagpcspdpdaegqrpygakfprt
tirddvrihrqvldrlgvrqiaavvgasmggmhtlewaffgpeyvrkivpiatscrqsgw
caawfetqrqciyddpkyldgeydvddqpvrgletarkianltykskpamderfhmapgv
qagrnissqdakkeingtdsgnshragqpieavssylryqaqkfaasfdancyiamtlkf
dthdisrgragsipealamitqpaliicarsdglysfdehvemgrsipnsrlcvvdtneg
hdffvmeadkvndavrgfldqslm

    Sequence, based on observed residues (ATOM records): (download) 
    >2vavK (K:)
nrfeasldaqdiarislftlesgvilrdvpvaykswgrmnvsrdncvivchtltssahvt
swwptlfgqgrafdtsryfiiclnylgspfgsagpcspdpygakfprttirddvrihrqv
ldrlgvrqiaavvgasmggmhtlewaffgpeyvrkivpiatscrqsgwcaawfetqrqci
yddpkyldgeydvddqpvrgletarkianltykskpamderfhmgqpieavssylryqaq
kfaasfdancyiamtlkfdthdisrgragsipealamitqpaliicarsdglysfdehve
mgrsipnsrlcvvdtneghdffvmeadkvndavrgfldqsl

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >2vavL (L:)
mlpsaqvarlkpdpfppslspiphgavtfaalapchnlpifssrqmlrdsltyshtsptm
spqianrfeasldaqdiarislftlesgvilrdvpvaykswgrmnvsrdncvivchtlts
sahvtswwptlfgqgrafdtsryfiiclnylgspfgsagpcspdpdaegqrpygakfprt
tirddvrihrqvldrlgvrqiaavvgasmggmhtlewaffgpeyvrkivpiatscrqsgw
caawfetqrqciyddpkyldgeydvddqpvrgletarkianltykskpamderfhmapgv
qagrnissqdakkeingtdsgnshragqpieavssylryqaqkfaasfdancyiamtlkf
dthdisrgragsipealamitqpaliicarsdglysfdehvemgrsipnsrlcvvdtneg
hdffvmeadkvndavrgfldqslm

    Sequence, based on observed residues (ATOM records): (download) 
    >2vavL (L:)
nrfeasldaqdiarislftlesgvilrdvpvaykswgrmnvsrdncvivchtltssahvt
swwptlfgqgrafdtsryfiiclnylgspfgsagpcspdpdpygakfprttirddvrihr
qvldrlgvrqiaavvgasmggmhtlewaffgpeyvrkivpiatscrqsgwcaawfetqrq
ciyddpkyldgeydvddqpvrgletarkianltykskpamderfhmqpieavssylryqa
qkfaasfdancyiamtlkfdthdisrgragsipealamitqpaliicarsdglysfdehv
emgrsipnsrlcvvdtneghdffvmeadkvndavrgfldq