PDB entry 2va2

View 2va2 on RCSB PDB site
Description: complex structure of sulfolobus solfataricus dpo4 and DNA duplex containing a hydrophobic thymine isostere 2,4-difluorotoluene nucleotide in the template strand
Class: transferase
Keywords: DNA-directed DNA polymerase, p2 DNA polymerase IV, nucleotidyltransferase, mutator protein, DNA replication, 2-4-difluorotoluene, DNA repair, DNA-binding, transferase, metal-binding, translesion DNA polymerase, 2, ddctp, cytoplasm, magnesium, DNA damage
Deposited on 2007-08-28, released 2007-10-30
The last revision prior to the SCOP 1.75 freeze date was dated 2007-12-18, with a file datestamp of 2007-12-14.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.211
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA polymerase IV
    Species: SULFOLOBUS SOLFATARICUS
    Database cross-references and differences (RAF-indexed):
    • PDB 2VA2 (6-23)
    • Uniprot Q97W02 (6-End)
    Domains in SCOP 1.75: d2va2a1, d2va2a2
  • Chain 'B':
    Compound: DNA polymerase IV
    Species: SULFOLOBUS SOLFATARICUS
    Database cross-references and differences (RAF-indexed):
    • PDB 2VA2 (6-23)
    • Uniprot Q97W02 (6-End)
    Domains in SCOP 1.75: d2va2b1, d2va2b2
  • Chain 'C':
    Compound: 5'-d(*gp*gp*gp*gp*gp*ap*ap*gp*gp*ap *cp*tp*a)-3'
  • Chain 'D':
    Compound: 5'-d(*tp*tp*cp*ap*gp*dftp*ap*gp*tp*cp*cp *tp*tp*cp*cp*cp*cp*c)-3'
  • Chain 'E':
    Compound: 5'-d(*gp*gp*gp*gp*gp*ap*ap*gp*gp*ap *cp*tp*a)-3'
  • Chain 'F':
    Compound: 5'-d(*tp*tp*cp*ap*gp*dftp*ap*gp*tp*cp*cp *tp*tp*cp*cp*cp*cp*c)-3'
  • Heterogens: CA, DCT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2va2A (A:)
hhhhhhmivlfvdfdyfyaqveevlnpslkgkpvvvcvfsgrfedsgavatanyearkfg
vkagipiveakkilpnavylpmrkevyqqvssrimnllreysekieiasideayldisdk
vrdyreaynlgleiknkilekekitvtvgisknkvfakiaadmakpngikviddeevkrl
ireldiadvpgignitaeklkklginklvdtlsiefdklkgmigeakakylislardeyn
epirtrvrksigrivtmkrnsrnleeikpylfraieesyykldkripkaihvvavtedld
ivsrgrtfphgisketaysesvkllqkileederkirrigvrfskfieaigldkffdt

    Sequence, based on observed residues (ATOM records): (download) 
    >2va2A (A:)
mivlfvdfdyfyaqveevlnpslkgkpvvvcvfsgrfedsgavatanyearkfgvkagip
iveakkilpnavylpmrkevyqqvssrimnllreysekieiasideayldisdkvrdyre
aynlgleiknkilekekitvtvgisknkvfakiaadmakpngikviddeevkrlireldi
advpgignitaeklkklginklvdtlsiefdklkgmigeakakylislardeynepirtr
vrksigrivtmkrnsrnleeikpylfraieesyykldkripkaihvvavtedldivsrgr
tfphgisketaysesvkllqkileederkirrigvrfskfiea

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2va2B (B:)
hhhhhhmivlfvdfdyfyaqveevlnpslkgkpvvvcvfsgrfedsgavatanyearkfg
vkagipiveakkilpnavylpmrkevyqqvssrimnllreysekieiasideayldisdk
vrdyreaynlgleiknkilekekitvtvgisknkvfakiaadmakpngikviddeevkrl
ireldiadvpgignitaeklkklginklvdtlsiefdklkgmigeakakylislardeyn
epirtrvrksigrivtmkrnsrnleeikpylfraieesyykldkripkaihvvavtedld
ivsrgrtfphgisketaysesvkllqkileederkirrigvrfskfieaigldkffdt

    Sequence, based on observed residues (ATOM records): (download) 
    >2va2B (B:)
hmivlfvdfdyfyaqveevlnpslkgkpvvvcvfsgrfedsgavatanyearkfgvkagi
piveakkilpnavylpmrkevyqqvssrimnllreysekieiasideayldisdkvrdyr
eaynlgleiknkilekekitvtvgisknkvfakiaadmakpngikviddeevkrlireld
iadvpgignitaeklkklginklvdtlsiefdklkgmigeakakylislardeynepirt
rvrksigrivtmkrnsrnleeikpylfraieesyykldkripkaihvvavtedldivsrg
rtfphgisketaysesvkllqkileederkirrigvrfskfiea

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    No sequence available.