PDB entry 2v9y

View 2v9y on RCSB PDB site
Description: Human aminoimidazole ribonucleotide synthetase
Class: ligase
Keywords: multifunctional enzyme, structural genomics consortium, nucleotide-binding, purine biosynthesis, sgc, airs, gart, ligase, transferase, ATP-binding, aminoimidazole ribonucleotide synthetase, phosphorylation, purine metabolism, structural genomics
Deposited on 2007-08-28, released 2007-09-11
The last revision prior to the SCOPe 2.08 freeze date was dated 2015-05-06, with a file datestamp of 2015-05-01.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: phosphoribosylformylglycinamidine cyclo-ligase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2V9Y
      • engineered mutation (291)
    • Uniprot P22102
    Domains in SCOPe 2.08: d2v9ya1, d2v9ya2
  • Chain 'B':
    Compound: phosphoribosylformylglycinamidine cyclo-ligase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2V9Y
      • engineered mutation (291)
    • Uniprot P22102
    Domains in SCOPe 2.08: d2v9yb1, d2v9yb2
  • Heterogens: SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2v9yA (A:)
hhhhhhkvdlggfaglfdlkaagfkdpllasgtdgvgtklkiaqlcnkhdtigqdlvamc
vndilaqgaeplffldyfscgkldlsvteavvagiakacgkagcallggetaempdmypp
geydlagfavgamerdqklphleritegdvvvgiassglhsngfslvrkivaksslqyss
papdgcgdqtlgdllltptriyshsllpvlrsghvkafahitggglleniprvlpeklgv
dldaqtwriprvfswlqqeghlseeemartfncgvgavlvvskeqteqilrgiqqhkeea
wvigsvvaraegsprvkvknliesmqingsvlkn

    Sequence, based on observed residues (ATOM records): (download) 
    >2v9yA (A:)
glfdlkaagfkdpllasgtdgvgtklkiaqlcnkhdtigqdlvamcvndilaqgaeplff
ldyfscgkldlsvteavvagiakacgkagcallggetaempdmyppgeydlagfavgame
rdqklphleritegdvvvgiassglhsngfslvrkivaksslqysspapdgcgdqtlgdl
lltptriyshsllpvlrsghvkafahitggglleniprvlpeklgvdldaqtwriprvfs
wlqqeghlseeemartfncgvgavlvvskeqteqilrgiqqhkeeawvigsvvarprvkv
knliesmqingsvl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2v9yB (B:)
hhhhhhkvdlggfaglfdlkaagfkdpllasgtdgvgtklkiaqlcnkhdtigqdlvamc
vndilaqgaeplffldyfscgkldlsvteavvagiakacgkagcallggetaempdmypp
geydlagfavgamerdqklphleritegdvvvgiassglhsngfslvrkivaksslqyss
papdgcgdqtlgdllltptriyshsllpvlrsghvkafahitggglleniprvlpeklgv
dldaqtwriprvfswlqqeghlseeemartfncgvgavlvvskeqteqilrgiqqhkeea
wvigsvvaraegsprvkvknliesmqingsvlkn

    Sequence, based on observed residues (ATOM records): (download) 
    >2v9yB (B:)
glfdlkaagfkdpllasgtdgvgtklkiaqlcnkhdtigqdlvamcvndilaqgaeplff
ldyfscgkldlsvteavvagiakacgkagcallggetaempdmyppgeydlagfavgame
rdqklphleritegdvvvgiassglhsngfslvrkivaksslqysspapdgcgdqtlgdl
lltptriyshsllpvlrsghvkafahitggglleniprvlpeklgvdldaqtwriprvfs
wlqqeghlseeemartfncgvgavlvvskeqteqilrgiqqhkeeawvigsvvarprvkv
knliesm