PDB entry 2v8h

View 2v8h on RCSB PDB site
Description: crystal structure of mutant e159a of beta-alanine synthase from saccharomyces kluyveri in complex with its substrate n-carbamyl-beta-alanine
Deposited on 2007-08-08, released 2007-10-02
The last revision was dated 2011-07-13, with a file datestamp of 2011-05-31.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.18
AEROSPACI score: 0.48 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: beta-alanine synthase
    Species: SACCHAROMYCES KLUYVERI [TaxId:4934]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q96W94 (Start-453)
      • engineered mutation (157)
      • expression tag (454-456)
  • Chain 'B':
    Compound: beta-alanine synthase
    Species: SACCHAROMYCES KLUYVERI [TaxId:4934]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q96W94 (Start-453)
      • engineered mutation (157)
      • expression tag (454-456)
  • Chain 'C':
    Compound: beta-alanine synthase
    Species: SACCHAROMYCES KLUYVERI [TaxId:4934]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q96W94 (Start-453)
      • engineered mutation (157)
      • expression tag (454-456)
  • Chain 'D':
    Compound: beta-alanine synthase
    Species: SACCHAROMYCES KLUYVERI [TaxId:4934]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q96W94 (Start-453)
      • engineered mutation (157)
      • expression tag (454-456)
  • Heterogens: ZN, URP, BCN, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >2v8hA (A:)
skdvsstittvsaspdgtlnlpaaaplsiasgrlnqtiletgsqfggvarwgqeshefgm
rrlagtaldgamrdwftneceslgckvkvdkignmfavypgknggkptatgshldtqpea
gkydgilgvlaglevlrtfkdnnyvpnydvcvvvwfnaegarfarsctgssvwshdlsle
eayglmsvgedkpesvydslknigyigdtpasykeneidahfelhieqgpiledenkaig
ivtgvqaynwqkvtvhgvgahagttpwrlrkdallmsskmivaaseiaqrhnglftcgii
dakpysvniipgevsftldfrhpsddvlatmlkeaaaefdrlikindggalsyesetlqv
spavnfhevciecvsrsafaqfkkdqvrqiwsgaghdscqtaphvptsmifipskdglsh
nyyeysspeeiengfkvllqaiinydnyrvirghqfpgddddkhhhhhhhhsgd

    Sequence, based on observed residues (ATOM records):
    >2v8hA (A:)
lsiasgrlnqtiletgsqfggvarwgqeshefgmrrlagtaldgamrdwftneceslgck
vkvdkignmfavypgknggkptatgshldtqpeagkydgilgvlaglevlrtfkdnnyvp
nydvcvvvwfnaegarfarsctgssvwshdlsleeayglmsvgedkpesvydslknigyi
gdtpasykeneidahfelhieqgpiledenkaigivtgvqaynwqkvtvhgvgahagttp
wrlrkdallmsskmivaaseiaqrhnglftcgiidakpysvniipgevsftldfrhpsdd
vlatmlkeaaaefdrlikindggalsyesetlqvspavnfhevciecvsrsafaqfkkdq
vrqiwsgaghdscqtaphvptsmifipskdglshnyyeysspeeiengfkvllqaiinyd
nyrvirghqfp

  • Chain 'B':
    Sequence, based on SEQRES records:
    >2v8hB (B:)
skdvsstittvsaspdgtlnlpaaaplsiasgrlnqtiletgsqfggvarwgqeshefgm
rrlagtaldgamrdwftneceslgckvkvdkignmfavypgknggkptatgshldtqpea
gkydgilgvlaglevlrtfkdnnyvpnydvcvvvwfnaegarfarsctgssvwshdlsle
eayglmsvgedkpesvydslknigyigdtpasykeneidahfelhieqgpiledenkaig
ivtgvqaynwqkvtvhgvgahagttpwrlrkdallmsskmivaaseiaqrhnglftcgii
dakpysvniipgevsftldfrhpsddvlatmlkeaaaefdrlikindggalsyesetlqv
spavnfhevciecvsrsafaqfkkdqvrqiwsgaghdscqtaphvptsmifipskdglsh
nyyeysspeeiengfkvllqaiinydnyrvirghqfpgddddkhhhhhhhhsgd

    Sequence, based on observed residues (ATOM records):
    >2v8hB (B:)
lsiasgrlnqtiletgsqfggvarwgqeshefgmrrlagtaldgamrdwftneceslgck
vkvdkignmfavypgknggkptatgshldtqpeagkydgilgvlaglevlrtfkdnnyvp
nydvcvvvwfnaegarfarsctgssvwshdlsleeayglmsvgedkpesvydslknigyi
gdtpasykeneidahfelhieqgpiledenkaigivtgvqaynwqkvtvhgvgahagttp
wrlrkdallmsskmivaaseiaqrhnglftcgiidakpysvniipgevsftldfrhpsdd
vlatmlkeaaaefdrlikindggalsyesetlqvspavnfhevciecvsrsafaqfkkdq
vrqiwsgaghdscqtaphvptsmifipskdglshnyyeysspeeiengfkvllqaiinyd
nyrvirghqfp

  • Chain 'C':
    Sequence, based on SEQRES records:
    >2v8hC (C:)
skdvsstittvsaspdgtlnlpaaaplsiasgrlnqtiletgsqfggvarwgqeshefgm
rrlagtaldgamrdwftneceslgckvkvdkignmfavypgknggkptatgshldtqpea
gkydgilgvlaglevlrtfkdnnyvpnydvcvvvwfnaegarfarsctgssvwshdlsle
eayglmsvgedkpesvydslknigyigdtpasykeneidahfelhieqgpiledenkaig
ivtgvqaynwqkvtvhgvgahagttpwrlrkdallmsskmivaaseiaqrhnglftcgii
dakpysvniipgevsftldfrhpsddvlatmlkeaaaefdrlikindggalsyesetlqv
spavnfhevciecvsrsafaqfkkdqvrqiwsgaghdscqtaphvptsmifipskdglsh
nyyeysspeeiengfkvllqaiinydnyrvirghqfpgddddkhhhhhhhhsgd

    Sequence, based on observed residues (ATOM records):
    >2v8hC (C:)
plsiasgrlnqtiletgsqfggvarwgqeshefgmrrlagtaldgamrdwftneceslgc
kvkvdkignmfavypgknggkptatgshldtqpeagkydgilgvlaglevlrtfkdnnyv
pnydvcvvvwfnaegarfarsctgssvwshdlsleeayglmsvgedkpesvydslknigy
igdtpasykeneidahfelhieqgpiledenkaigivtgvqaynwqkvtvhgvgahagtt
pwrlrkdallmsskmivaaseiaqrhnglftcgiidakpysvniipgevsftldfrhpsd
dvlatmlkeaaaefdrlikindggalsyesetlqvspavnfhevciecvsrsafaqfkkd
qvrqiwsgaghdscqtaphvptsmifipskdglshnyyeysspeeiengfkvllqaiiny
dnyrvirghqfp

  • Chain 'D':
    Sequence, based on SEQRES records:
    >2v8hD (D:)
skdvsstittvsaspdgtlnlpaaaplsiasgrlnqtiletgsqfggvarwgqeshefgm
rrlagtaldgamrdwftneceslgckvkvdkignmfavypgknggkptatgshldtqpea
gkydgilgvlaglevlrtfkdnnyvpnydvcvvvwfnaegarfarsctgssvwshdlsle
eayglmsvgedkpesvydslknigyigdtpasykeneidahfelhieqgpiledenkaig
ivtgvqaynwqkvtvhgvgahagttpwrlrkdallmsskmivaaseiaqrhnglftcgii
dakpysvniipgevsftldfrhpsddvlatmlkeaaaefdrlikindggalsyesetlqv
spavnfhevciecvsrsafaqfkkdqvrqiwsgaghdscqtaphvptsmifipskdglsh
nyyeysspeeiengfkvllqaiinydnyrvirghqfpgddddkhhhhhhhhsgd

    Sequence, based on observed residues (ATOM records):
    >2v8hD (D:)
lsiasgrlnqtiletgsqfggvarwgqeshefgmrrlagtaldgamrdwftneceslgck
vkvdkignmfavypgknggkptatgshldtqpeagkydgilgvlaglevlrtfkdnnyvp
nydvcvvvwfnaegarfarsctgssvwshdlsleeayglmsvgedkpesvydslknigyi
gdtpasykeneidahfelhieqgpiledenkaigivtgvqaynwqkvtvhgvgahagttp
wrlrkdallmsskmivaaseiaqrhnglftcgiidakpysvniipgevsftldfrhpsdd
vlatmlkeaaaefdrlikindggalsyesetlqvspavnfhevciecvsrsafaqfkkdq
vrqiwsgaghdscqtaphvptsmifipskdglshnyyeysspeeiengfkvllqaiinyd
nyrvirghqfp