PDB entry 2v7w

View 2v7w on RCSB PDB site
Description: x-ray crystal structure of 5'-fluorodeoxyadenosine synthase s158g mutant complexed with 5'-fluorodeoxyadenosin
Class: transferase
Keywords: fluorination, transferase, biosynthetic protein
Deposited on 2007-08-02, released 2008-08-12
The last revision prior to the SCOP 1.75 freeze date was dated 2008-08-19, with a file datestamp of 2008-08-15.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.18889
AEROSPACI score: 0.56 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 5'-fluoro-5'-deoxyadenosine synthase
    Species: Streptomyces cattleya
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q70GK9
      • engineered mutation (157)
    Domains in SCOP 1.75: d2v7wa1, d2v7wa2
  • Chain 'B':
    Compound: 5'-fluoro-5'-deoxyadenosine synthase
    Species: Streptomyces cattleya
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q70GK9
      • engineered mutation (157)
    Domains in SCOP 1.75: d2v7wb1, d2v7wb2
  • Chain 'C':
    Compound: 5'-fluoro-5'-deoxyadenosine synthase
    Species: Streptomyces cattleya
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q70GK9
      • engineered mutation (157)
    Domains in SCOP 1.75: d2v7wc1, d2v7wc2
  • Heterogens: 5FD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2v7wA (A:)
maanstrrpiiafmsdlgttddsvaqckglmysicpdvtvvdvchsmtpwdveegaryiv
dlprffpegtvfatttypatgtttrsvavrikqaakggargqwagsgagferaegsyiyi
apnngllttvleehgyleayevtspkvipeqpeptfygremvaipsahlaagfplsevgr
pledheivrfnrpaveqdgealvgvvsaidhpfgnvwtnihrtdlekagigygarlrltl
dgvlpfeapltptfadageigniaiylnsrgylsiarnaaslaypyhlkegmsarvear

    Sequence, based on observed residues (ATOM records): (download) 
    >2v7wA (A:)
rpiiafmsdlgttddsvaqckglmysicpdvtvvdvchsmtpwdveegaryivdlprffp
egtvfatttypatgtttrsvavrikqaakggargqwagsgagferaegsyiyiapnngll
ttvleehgyleayevtspkvipeqpeptfygremvaipsahlaagfplsevgrpledhei
vrfnrpaveqdgealvgvvsaidhpfgnvwtnihrtdlekagigygarlrltldgvlpfe
apltptfadageigniaiylnsrgylsiarnaaslaypyhlkegmsarvea

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2v7wB (B:)
maanstrrpiiafmsdlgttddsvaqckglmysicpdvtvvdvchsmtpwdveegaryiv
dlprffpegtvfatttypatgtttrsvavrikqaakggargqwagsgagferaegsyiyi
apnngllttvleehgyleayevtspkvipeqpeptfygremvaipsahlaagfplsevgr
pledheivrfnrpaveqdgealvgvvsaidhpfgnvwtnihrtdlekagigygarlrltl
dgvlpfeapltptfadageigniaiylnsrgylsiarnaaslaypyhlkegmsarvear

    Sequence, based on observed residues (ATOM records): (download) 
    >2v7wB (B:)
rpiiafmsdlgttddsvaqckglmysicpdvtvvdvchsmtpwdveegaryivdlprffp
egtvfatttypatgtttrsvavrikqaakggargqwagsgagferaegsyiyiapnngll
ttvleehgyleayevtspkvipeqpeptfygremvaipsahlaagfplsevgrpledhei
vrfnrpaveqdgealvgvvsaidhpfgnvwtnihrtdlekagigygarlrltldgvlpfe
apltptfadageigniaiylnsrgylsiarnaaslaypyhlkegmsarvea

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2v7wC (C:)
maanstrrpiiafmsdlgttddsvaqckglmysicpdvtvvdvchsmtpwdveegaryiv
dlprffpegtvfatttypatgtttrsvavrikqaakggargqwagsgagferaegsyiyi
apnngllttvleehgyleayevtspkvipeqpeptfygremvaipsahlaagfplsevgr
pledheivrfnrpaveqdgealvgvvsaidhpfgnvwtnihrtdlekagigygarlrltl
dgvlpfeapltptfadageigniaiylnsrgylsiarnaaslaypyhlkegmsarvear

    Sequence, based on observed residues (ATOM records): (download) 
    >2v7wC (C:)
rpiiafmsdlgttddsvaqckglmysicpdvtvvdvchsmtpwdveegaryivdlprffp
egtvfatttypatgtttrsvavrikqaakggargqwagsgagferaegsyiyiapnngll
ttvleehgyleayevtspkvipeqpeptfygremvaipsahlaagfplsevgrpledhei
vrfnrpaveqdgealvgvvsaidhpfgnvwtnihrtdlekagigygarlrltldgvlpfe
apltptfadageigniaiylnsrgylsiarnaaslaypyhlkegmsarvea