PDB entry 2v64

View 2v64 on RCSB PDB site
Description: Crystallographic structure of the conformational dimer of the Spindle Assembly Checkpoint protein Mad2.
Class: cell cycle
Keywords: spindle assembly checkpoint, mad2, nucleus, mitosis, apoptosis, cell cycle, cell division, phosphorylation, conformational dimer
Deposited on 2007-07-13, released 2007-11-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2016-12-21, with a file datestamp of 2016-12-16.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: N/A
AEROSPACI score: 0.15 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: mitotic spindle assembly checkpoint protein mad2a
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2V64 (Start-8)
    • Uniprot Q13257 (9-212)
    Domains in SCOPe 2.08: d2v64a2, d2v64a3
  • Chain 'B':
    Compound: mbp1
    Species: synthetic construct, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):
    • PDB 2V64 (0-End)
  • Chain 'C':
    Compound: mitotic spindle assembly checkpoint protein mad2a
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2V64 (Start-8)
    • Uniprot Q13257 (9-212)
    Domains in SCOPe 2.08: d2v64c2, d2v64c3
  • Chain 'D':
    Compound: mitotic spindle assembly checkpoint protein mad2a
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2V64 (116-118)
    • Uniprot Q13257 (119-End)
    Domains in SCOPe 2.08: d2v64d_
  • Chain 'E':
    Compound: mitotic spindle assembly checkpoint protein mad2a
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2v64e_
  • Chain 'F':
    Compound: mitotic spindle assembly checkpoint protein mad2a
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2V64 (Start-8)
    • Uniprot Q13257 (9-212)
    Domains in SCOPe 2.08: d2v64f2, d2v64f3
  • Chain 'G':
    Compound: mbp1
    Species: synthetic construct, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):
    • PDB 2V64 (0-End)
  • Chain 'H':
    Compound: mitotic spindle assembly checkpoint protein mad2a
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2V64 (116-118)
    • Uniprot Q13257 (119-End)
    Domains in SCOPe 2.08: d2v64h_
  • Chain 'I':
    Compound: mbp1
    Species: synthetic construct, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):
    • PDB 2V64 (0-11)
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2v64A (A:)
mhhhhhhgsalqlsreqgitlrgsaeivaeffsfginsilyqrgiypsetftrvqkyglt
llvttdlelikylnnvveqlkdwlykcsvqklvvvisniesgevlerwqfdiecdktakd
dsapreksqkaiqdeirsvirqitatvtflpllevscsfdlliytdkdlvvpekweesgp
qfitnseevrlrsftttihkvnsmvaykipvnd

    Sequence, based on observed residues (ATOM records): (download) 
    >2v64A (A:)
hhhhhgsalqlsreqgitlrgsaeivaeffsfginsilyqrgiypsetftrvqkygltll
vttdlelikylnnvveqlkdwlykcsvqklvvvisniesgevlerwqfdiecdktakdds
apreksqkaiqdeirsvirqitatvtflpllevscsfdlliytdkdlvvpekweesgpqf
itnseevrlrsftttihkvnsmvaykipvnd

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2v64C (C:)
mhhhhhhgsalqlsreqgitlrgsaeivaeffsfginsilyqrgiypsetftrvqkyglt
llvttdlelikylnnvveqlkdwlykcsvqklvvvisniesgevlerwqfdiecdktakd
dsapreksqkaiqdeirsvirqitatvtflpllevscsfdlliytdkdlvvpekweesgp
qfitnseevrlrsftttihkvnsmvaykipvnd

    Sequence, based on observed residues (ATOM records): (download) 
    >2v64C (C:)
hhhhhgsalqlsreqgitlrgsaeivaeffsfginsilyqrgiypsetftrvqkygltll
vttdlelikylnnvveqlkdwlykcsvqklvvvisniesgevlerwqfdiecdktakdds
apreksqkaiqdeirsvirqitatvtflpllevscsfdlliytdkdlvvpekweesgpqf
itnseevrlrsftttihkvnsmvaykipvnd

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2v64D (D:)
mhhhhhhgsalqlsreqgitlrgsaeivaeffsfginsilyqrgiypsetftrvqkyglt
llvttdlelikylnnvveqlkdwlykcsvqklvvvisniesgevlerwqfdiecdkgsge
ksqkaiqdeirsvirqitatvtflpllevscsfdlliytdkdlvvpekweesgpqfitns
eevrlrsftttihkvnsmvaykipvnd

    Sequence, based on observed residues (ATOM records): (download) 
    >2v64D (D:)
eqgitlrgsaeivaeffsfginsilyqrgiypsetftrvqkygltllvttdlelikylnn
vveqlkdwlykcsvqklvvvisniesgevlerwqfdiecdkgsgeksqkaiqdeirsvir
qitatvtflpllevscsfdlliytdkdlpqfitnseevrlrsftttihkvns

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2v64E (E:)
mhhhhhhgsalqlsreqgitlrgsaeivaeffsfginsilyqrgiypsetftrvqkyglt
llvttdlelikylnnvveqlkdwlykcsvqklvvvisniesgevlerwqfdiecdkgsge
ksqkaiqdeirsvirqitatvtflpllevscsfdlliytdkdlvvpekweesgpqfitns
eevrlrsftttihkvnsmvaykipvnd

    Sequence, based on observed residues (ATOM records): (download) 
    >2v64E (E:)
qgitlrgsaeivaeffsfginsilyqrgiypsetftrvqkygltllvttdlelikylnnv
veqlkdwlykcsvqklvvvisniesgevlerwqfdiecdksqkaiqdeirsvirqitatv
tflpllevscsfdlliytdkdlvvpekweesgpqfitnseevrlrsftttihkvns

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >2v64F (F:)
mhhhhhhgsalqlsreqgitlrgsaeivaeffsfginsilyqrgiypsetftrvqkyglt
llvttdlelikylnnvveqlkdwlykcsvqklvvvisniesgevlerwqfdiecdktakd
dsapreksqkaiqdeirsvirqitatvtflpllevscsfdlliytdkdlvvpekweesgp
qfitnseevrlrsftttihkvnsmvaykipvnd

    Sequence, based on observed residues (ATOM records): (download) 
    >2v64F (F:)
hhhhhgsalqlsreqgitlrgsaeivaeffsfginsilyqrgiypsetftrvqkygltll
vttdlelikylnnvveqlkdwlykcsvqklvvvisniesgevlerwqfdiecdktakdds
apreksqkaiqdeirsvirqitatvtflpllevscsfdlliytdkdlvvpekweesgpqf
itnseevrlrsftttihkvnsmvaykipvnd

  • Chain 'G':
    No sequence available.

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >2v64H (H:)
mhhhhhhgsalqlsreqgitlrgsaeivaeffsfginsilyqrgiypsetftrvqkyglt
llvttdlelikylnnvveqlkdwlykcsvqklvvvisniesgevlerwqfdiecdkgsge
ksqkaiqdeirsvirqitatvtflpllevscsfdlliytdkdlvvpekweesgpqfitns
eevrlrsftttihkvnsmvaykipvnd

    Sequence, based on observed residues (ATOM records): (download) 
    >2v64H (H:)
qgitlrgsaeivaeffsfginsilyqrgiypsetftrvqkygltllvttdlelikylnnv
veqlkdwlykcsvqklvvvisniesgevlerwqfdiecdkgsgeksqkaiqdeirsvirq
itatvtflpllevscsfdlliytdkdlvvpekweesgpqfitnseevrlrsftttihkvn
s

  • Chain 'I':
    No sequence available.