PDB entry 2v5e

View 2v5e on RCSB PDB site
Description: The structure of the GDNF:Coreceptor complex: Insights into RET signalling and heparin binding.
Class: receptor/glycoprotein complex
Keywords: RECEPTOR-GLYCOPROTEIN COMPLEX, ALTERNATIVE SPLICING, CELL MEMBRANE, GROWTH FACTOR, LIGAND-CORECEPTOR, GPI-ANCHOR, LIPOPROTEIN, POLYMORPHISM, GLYCOPROTEIN, MEMBRANE, RECEPTOR, SECRETED, GFRALPHA1, CLEAVAGE ON PAIR OF BASIC RESIDUES, RECEPTOR-GLYCOPROTEIN COMPLEX complex
Deposited on 2008-10-03, released 2008-10-21
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-06-29.
Experiment type: XRAY
Resolution: 2.35 Å
R-factor: N/A
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: gdnf family receptor alpha-1
  Species: Rattus norvegicus [TaxId:10116]
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q62997 (0-199)
• Chain 'B':
  Compound: glial cell line-derived neurotrophic factor
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P39905 (0-100)
  Domains in SCOPe 2.08: d2v5eb_
• Heterogens: EDO, NAG, HOH

PDB Chain Sequences:

• Chain 'A':
  No sequence available.
  
  
• Chain 'B':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2v5eB (B:)
  qrgknrgcvltaihlnvtdlglgyetkeelifrycsgscdaaettydkilknlsrnrrlv
  sdkvgqaccrpiafdddlsflddnlvyhilrkhsakrcgci