PDB entry 2v4m

View 2v4m on RCSB PDB site
Description: The isomerase domain of human glutamine-fructose-6-phosphate transaminase 1 (GFPT1) in complex with fructose 6-phosphate
Class: transferase
Keywords: phosphoprotein, aminotransferase, fructose 6-phosphate, alternative splicing, glutamine amidotransferase, dimer, isomerase, sis domains, transferase
Deposited on 2008-09-26, released 2008-10-07
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-01-17, with a file datestamp of 2018-01-12.
Experiment type: XRAY
Resolution: 2.29 Å
R-factor: N/A
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2v4ma_
  • Chain 'B':
    Compound: glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2v4mb_
  • Chain 'C':
    Compound: glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2v4mc_
  • Chain 'D':
    Compound: glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2v4md_
  • Heterogens: F6R, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2v4mA (A:)
mghhhhhhqqimkgnfssfmqkeifeqpesvvntmrgrvnfddytvnlgglkdhikeiqr
crrliliacgtsyhagvatrqvleeltelpvmvelasdfldrntpvfrddvcfflsqsge
tadtlmglryckergaltvgitntvgssisretdcgvhinagpeigvastkaytsqfvsl
vmfalmmcddrismqerrkeimlglkrlpdlikevlsmddeiqklatelyhqksvlimgr
gyhyatclegalkikeitymhsegilagelkhgplalvdklmpvimiimrdhtyakcqna
lqqvvarqgrpvvicdkedtetikntkrtikvphsvdclqgilsviplqllafhlavlrg
ydvdfprnlaksvtve

    Sequence, based on observed residues (ATOM records): (download) 
    >2v4mA (A:)
kgnfssfmqkeifeqpesvvntmrgrvnfddytvnlgglkdhikeiqrcrrliliacgts
yhagvatrqvleeltelpvmvelasdfldrntpvfrddvcfflsqsgetadtlmglryck
ergaltvgitntvgssisretdcgvhinagpeigvastkaytsqfvslvmfalmmcddri
smqerrkeimlglkrlpdlikevlsmddeiqklatelyhqksvlimgrgyhyatclegal
kikeitymhsegilagelkhgplalvdklmpvimiimrdhtyakcqnalqqvvarqgrpv
vicdkedtetikntkrtikvphsvdclqgilsviplqllafhlavlrgydvd

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2v4mB (B:)
mghhhhhhqqimkgnfssfmqkeifeqpesvvntmrgrvnfddytvnlgglkdhikeiqr
crrliliacgtsyhagvatrqvleeltelpvmvelasdfldrntpvfrddvcfflsqsge
tadtlmglryckergaltvgitntvgssisretdcgvhinagpeigvastkaytsqfvsl
vmfalmmcddrismqerrkeimlglkrlpdlikevlsmddeiqklatelyhqksvlimgr
gyhyatclegalkikeitymhsegilagelkhgplalvdklmpvimiimrdhtyakcqna
lqqvvarqgrpvvicdkedtetikntkrtikvphsvdclqgilsviplqllafhlavlrg
ydvdfprnlaksvtve

    Sequence, based on observed residues (ATOM records): (download) 
    >2v4mB (B:)
gnfssfmqkeifeqpesvvntmrgrvnfddytvnlgglkdhikeiqrcrrliliacgtsy
hagvatrqvleeltelpvmvelasdfldrntpvfrddvcfflsqsgetadtlmglrycke
rgaltvgitntvgssisretdcgvhinagpeigvastkaytsqfvslvmfalmmcddris
mqerrkeimlglkrlpdlikevlsmddeiqklatelyhqksvlimgrgyhyatclegalk
ikeitymhsegilagelkhgplalvdklmpvimiimrdhtyakcqnalqqvvarqgrpvv
icdkedtetikntkrtikvphsvdclqgilsviplqllafhlavlrgydvd

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2v4mC (C:)
mghhhhhhqqimkgnfssfmqkeifeqpesvvntmrgrvnfddytvnlgglkdhikeiqr
crrliliacgtsyhagvatrqvleeltelpvmvelasdfldrntpvfrddvcfflsqsge
tadtlmglryckergaltvgitntvgssisretdcgvhinagpeigvastkaytsqfvsl
vmfalmmcddrismqerrkeimlglkrlpdlikevlsmddeiqklatelyhqksvlimgr
gyhyatclegalkikeitymhsegilagelkhgplalvdklmpvimiimrdhtyakcqna
lqqvvarqgrpvvicdkedtetikntkrtikvphsvdclqgilsviplqllafhlavlrg
ydvdfprnlaksvtve

    Sequence, based on observed residues (ATOM records): (download) 
    >2v4mC (C:)
fssfmqkeifeqpesvvntmrgrvnfddytvnlgglkdhikeiqrcrrliliacgtsyha
gvatrqvleeltelpvmvelasdfldrntpvfrddvcfflsqsgetadtlmglryckerg
altvgitntvgssisretdcgvhinagpeigvastkaytsqfvslvmfalmmcddrismq
errkeimlglkrlpdlikevlsmddeiqklatelyhqksvlimgrgyhyatclegalkik
eitymhsegilagelkhgplalvdklmpvimiimrdhtyakcqnalqqvvarqgrpvvic
dkedtetikntkrtikvphsvdclqgilsviplqllafhlavlrgydvdfpr

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2v4mD (D:)
mghhhhhhqqimkgnfssfmqkeifeqpesvvntmrgrvnfddytvnlgglkdhikeiqr
crrliliacgtsyhagvatrqvleeltelpvmvelasdfldrntpvfrddvcfflsqsge
tadtlmglryckergaltvgitntvgssisretdcgvhinagpeigvastkaytsqfvsl
vmfalmmcddrismqerrkeimlglkrlpdlikevlsmddeiqklatelyhqksvlimgr
gyhyatclegalkikeitymhsegilagelkhgplalvdklmpvimiimrdhtyakcqna
lqqvvarqgrpvvicdkedtetikntkrtikvphsvdclqgilsviplqllafhlavlrg
ydvdfprnlaksvtve

    Sequence, based on observed residues (ATOM records): (download) 
    >2v4mD (D:)
nfssfmqkeifeqpesvvntmrgrvnfddytvnlgglkdhikeiqrcrrliliacgtsyh
agvatrqvleeltelpvmvelasdfldrntpvfrddvcfflsqsgetadtlmglrycker
galtvgitntvgssisretdcgvhinagpeigvastkaytsqfvslvmfalmmcddrism
qerrkeimlglkrlpdlikevlsmddeiqklatelyhqksvlimgrgyhyatclegalki
keitymhsegilagelkhgplalvdklmpvimiimrdhtyakcqnalqqvvarqgrpvvi
cdkedtetikntkrtikvphsvdclqgilsviplqllafhlavlrgydvd