PDB entry 2v2w
View 2v2w on RCSB PDB site
Description: t cell cross-reactivity and conformational changes during tcr engagement
Class: immune system
Keywords: immunoglobulin domain, complex (antigen-peptide), tcr, hiv, MHC, aids, MHC I, hla-a2, membrane, immunoglobulin domain, host-virus interaction, pyrrolidone carboxylic acid, immune system, complex (antigen/peptide), ubl conjugation, immune response, disease mutation, polymorphism, glycoprotein, transmembrane
Deposited on
2007-06-07, released
2007-11-06
The last revision prior to the SCOP 1.75 freeze date was dated
2007-11-06, with a file datestamp of
2007-11-02.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: 0.20048
AEROSPACI score: 0.68
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: HLA class I histocompatibility antigen, A-2 alpha chain
Species: HOMO SAPIENS
Database cross-references and differences (RAF-indexed):
Domains in SCOP 1.75: d2v2wa1, d2v2wa2 - Chain 'B':
Compound: beta-2 microglobulin
Species: HOMO SAPIENS
Database cross-references and differences (RAF-indexed):
- PDB 2V2W (1-9)
- Uniprot P61769 (1-99)
Domains in SCOP 1.75: d2v2wb1 - Chain 'C':
Compound: hiv p17
- Chain 'D':
Compound: HLA class I histocompatibility antigen, A-2 alpha chain
Species: HOMO SAPIENS
Database cross-references and differences (RAF-indexed):
Domains in SCOP 1.75: d2v2wd1, d2v2wd2 - Chain 'E':
Compound: beta-2 microglobulin
Species: HOMO SAPIENS
Database cross-references and differences (RAF-indexed):
- PDB 2V2W (1-9)
- Uniprot P61769 (1-99)
Domains in SCOP 1.75: d2v2we1 - Chain 'F':
Compound: hiv p17
- Heterogens: HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>2v2wA (A:)
gshsmryfftsvsrpgrgeprfiavgyvddtqfvrfdsdaasqrmeprapwieqegpeyw
dgetrkvkahsqthrvdlgtlrgyynqseagshtvqrmygcdvgsdwrflrgyhqyaydg
kdyialkedlrswtaadmaaqttkhkweaahvaeqlraylegtcvewlrrylengketlq
rtdapkthmthhavsdheatlrcwalsfypaeitltwqrdgedqtqdtelvetrpagdgt
fqkwaavvvpsgqeqrytchvqheglpkpltlrwep
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>2v2wB (B:)
miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
- Chain 'C':
No sequence available.
- Chain 'D':
Sequence; same for both SEQRES and ATOM records: (download)
>2v2wD (D:)
gshsmryfftsvsrpgrgeprfiavgyvddtqfvrfdsdaasqrmeprapwieqegpeyw
dgetrkvkahsqthrvdlgtlrgyynqseagshtvqrmygcdvgsdwrflrgyhqyaydg
kdyialkedlrswtaadmaaqttkhkweaahvaeqlraylegtcvewlrrylengketlq
rtdapkthmthhavsdheatlrcwalsfypaeitltwqrdgedqtqdtelvetrpagdgt
fqkwaavvvpsgqeqrytchvqheglpkpltlrwep
- Chain 'E':
Sequence; same for both SEQRES and ATOM records: (download)
>2v2wE (E:)
miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
- Chain 'F':
No sequence available.