PDB entry 2v2e

View 2v2e on RCSB PDB site
Description: structure of isoniazid (inh) bound to cytochrome c peroxidase mutant n184r y36a
Class: oxidoreductase
Keywords: cytochrome c peroxidase, transit peptide, organic radical, hydrogen peroxide, inh, ccp, iron, heme, isoniazid, peroxidase, mitochondrion, metal-binding, oxidoreductase
Deposited on 2007-06-05, released 2007-12-04
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.68 Å
R-factor: 0.166
AEROSPACI score: 0.58 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: cytochrome c peroxidase
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
    • PDB 2V2E
      • engineered mutation (38)
      • engineered mutation (183)
      • conflict (209)
    • Uniprot P00431 (3-293)
    Domains in SCOPe 2.05: d2v2ea_
  • Heterogens: HEM, ISZ, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2v2eA (A:)
mktlvhvasvekgrsyedfqkvynaialklreddeydnaigygpvlvrlawhtsgtwdkh
dntggsyggtyrfkkefndpsnaglqngfkflepihkefpwissgdlfslggvtavqemq
gpkipwrcgrvdtpedttpdngrlpdadkdadyvrtffqrlnmndrevvalmgahalgkt
hlkrsgyegpwgaannvftnefylnllnenwklekndanneqwdsksgymmlptdysliq
dpkylsivkeyandqdkffkdfskafekllengitfpkdapspfifktleeqgl

    Sequence, based on observed residues (ATOM records): (download) 
    >2v2eA (A:)
lvhvasvekgrsyedfqkvynaialklreddeydnaigygpvlvrlawhtsgtwdkhdnt
ggsyggtyrfkkefndpsnaglqngfkflepihkefpwissgdlfslggvtavqemqgpk
ipwrcgrvdtpedttpdngrlpdadkdadyvrtffqrlnmndrevvalmgahalgkthlk
rsgyegpwgaannvftnefylnllnenwklekndanneqwdsksgymmlptdysliqdpk
ylsivkeyandqdkffkdfskafekllengitfpkdapspfifktleeqgl