PDB entry 2v1d

View 2v1d on RCSB PDB site
Description: structural basis of lsd1-corest selectivity in histone h3 recognition
Deposited on 2007-05-23, released 2007-05-29
The last revision was dated 2009-12-29, with a file datestamp of 2009-12-24.
Experiment type: XRAY
Resolution: 3.1 Å
R-factor: 0.224
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Lysine-specific histone demethylase 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: rest corepressor 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Histone H3.1t
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q16695 (0-End)
      • engineered mutation (3)
  • Heterogens: FAD

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >2v1dA (A:)
mdeslanlsedeyyseeernakaekekklpppppqappeeenesepeepsgvegaafqsr
lphdrmtsqeaacfpdiisgpqqtqkvflfirnrtlqlwldnpkiqltfeatlqqleapy
nsdtvlvhrvhsylerhglinfgiykrikplptkktgkviiigsgvsglaaarqlqsfgm
dvtlleardrvggrvatfrkgnyvadlgamvvtglggnpmavvskqvnmelakikqkcpl
yeangqavpkekdemveqefnrlleatsylshqldfnvlnnkpvslgqalevviqlqekh
vkdeqiehwkkivktqeelkellnkmvnlkekikelhqqykeasevkpprditaeflvks
khrdltalckeydelaetqgkleeklqeleanppsdvylssrdrqildwhfanlefanat
plstlslkhwdqdddfeftgshltvrngyscvpvalaegldiklntavrqvrytasgcev
iavntrstsqtfiykcdavlctlplgvlkqqppavqfvpplpewktsavqrmgfgnlnkv
vlcfdrvfwdpsvnlfghvgsttasrgelflfwnlykapillalvageaagimenisddv
ivgrclailkgifgssavpqpketvvsrwradpwargsysyvaagssgndydlmaqpitp
gpsipgapqpiprlffagehtirnypatvhgallsglreagriadqflgamytlprqatp
gvpaqqspsm

    Sequence, based on observed residues (ATOM records):
    >2v1dA (A:)
psgvegaafqsrlphdrmtsqeaacfpdiisgpqqtqkvflfirnrtlqlwldnpkiqlt
featlqqleapynsdtvlvhrvhsylerhglinfgiykrikplptkktgkviiigsgvsg
laaarqlqsfgmdvtlleardrvggrvatfrkgnyvadlgamvvtglggnpmavvskqvn
melakikqkcplyeangqavpkekdemveqefnrlleatsylshqldfnvlnnkpvslgq
alevviqlqekhvkdeqiehwkkivktqeelkellnkmvnlkekikelhqqykeasevkp
prditaeflvkskhrdltalckeydelaetqgkleeklqeleanppsdvylssrdrqild
whfanlefanatplstlslkhwdqdddfeftgshltvrngyscvpvalaegldiklntav
rqvrytasgceviavntrstsqtfiykcdavlctlplgvlkqqppavqfvpplpewktsa
vqrmgfgnlnkvvlcfdrvfwdpsvnlfghvgsttasrgelflfwnlykapillalvage
aagimenisddvivgrclailkgifgssavpqpketvvsrwradpwargsysyvaagssg
ndydlmaqpitpgpsipgapqpiprlffagehtirnypatvhgallsglreagriadqfl
gamytl

  • Chain 'B':
    Sequence, based on SEQRES records:
    >2v1dB (B:)
rakrkppkgmflsqedveavsanataattvlrqldmelvsvkrqiqnikqtnsalkekld
ggiepyrlpeviqkcnarwtteeqllavqairkygrdfqaisdvignksvvqvknffvny
rrrfnidevlqeweaehgkeetngpsnqkpvkspdnsikmpeeedeapvldvryasas

    Sequence, based on observed residues (ATOM records):
    >2v1dB (B:)
rkppkgmflsqedveavsanataattvlrqldmelvsvkrqiqnikqtnsalkekldggi
epyrlpeviqkcnarwtteeqllavqairkygrdfqaisdvignksvvqvknffvnyrrr
fnidevlqeweae

  • Chain 'C':
    Sequence, based on SEQRES records:
    >2v1dC (C:)
artmqtarkstggkaprkqla

    Sequence, based on observed residues (ATOM records):
    >2v1dC (C:)
artmqtarkstggkap