PDB entry 2v0g

View 2v0g on RCSB PDB site
Description: leucyl-trna synthetase from thermus thermophilus complexed with a trna(leu) transcript with 5-fluoro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole (an2690) forming an adduct to the ribose of adenosine-76 in the enzyme editing site.
Deposited on 2007-05-14, released 2007-07-03
The last revision was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 3.5 Å
R-factor: 0.249
AEROSPACI score: 0.12 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: aminoacyl-tRNA synthetase
    Species: THERMUS THERMOPHILUS [TaxId:274]
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: trnaleu
  • Chain 'D':
    Compound: aminoacyl-tRNA synthetase
    Species: THERMUS THERMOPHILUS [TaxId:274]
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: trnaleu
  • Heterogens: LEU, ZN, HG, SO4

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >2v0gA (A:)
mekynphaieakwqrfweekgfmkakdlpggrgkqyvlvmfpypsgdlhmghlknytmgd
vlarfrrmqgyevlhpmgwdafglpaenaalkfgvhpkdwtyanirqakeslrlmgilyd
wdrevttcepeyyrwnqwiflkmwekglayrakglvnwcpkcqtvlaneqvvegrcwrhe
dtpvekreleqwylritayaerllkdleglnwpekvkamqrawigrsegaeilfpvegke
vripvfttrpdtlfgatflvlapehpltlelaapekreevlayveaakrkteierqaegr
ektgvflgayalnpatgeripiwtadyvlfgygtgaimavpahdqrdyefarkfglpikk
vierpgeplpeplerayeepgimvnsgpfdgteseegkrkviawleekglgkgrvtyrlr
dwlisrqrywgtpipmvhceacgvvpvpeeelpvllpdlkdvedirpkgkspleahpefy
ettcpkcggpakrdtdtmdtffdsswyylrytdphndrlpfdpekanawmpvdqyiggve
havlhllysrfftkflhdlgmvkveepfqglftqgmvlawtdfgpvevegsvvrlpeptr
irleipesalsledvrkmgaelrphedgtlhlwkpavmskskgngvmvgpfvkeqgadia
ritilfaappenemvwteegvqgawrflnriyrrvaedrealletsgvfqaealegkdre
lygklhetlkkvtedlealrfntaiaalmeflnalyeyrkdrpvtpvyrtairyylqmlf
pfaphlaeelwhwfwpdslfeagwpeldekalekdvvevavqvngrvrgtihipkdaple
varaealkvrnvrahlegkevvkeiyvpgkilnlvvrg

    Sequence, based on observed residues (ATOM records):
    >2v0gA (A:)
mekynphaieakwqrfweekgfmkakdlpggrgkqyvlvmfpypsgdlhmghlknytmgd
vlarfrrmqgyevlhpmgwdafglpaenaalkfgvhpkdwtyanirqakeslrlmgilyd
wdrevttcepeyyrwnqwiflkmwekglayrakglvnwcpkcqtvlaneqvvegrcwrhe
dtpvekreleqwylritayaerllkdleglnwpekvkamqrawigrsegaeilfpvegke
vripvfttrpdtlfgatflvlapehpltlelaapekreevlayveaakrkteierqaegr
ektgvflgayalnpatgeripiwtadyvlfgygtgaimavpahdqrdyefarkfglpikk
vierpgeplpeplerayeepgimvnsgpfdgteseegkrkviawleekglgkgrvtyrlr
dwlisrqrywgtpipmvhceacgvvpvpeeelpvllpdlkdvedirpkgkspleahpefy
ettcpkcggpakrdtdtmdtffdsswyylrytdphndrlpfdpekanawmpvdqyiggve
havlhllysrfftkflhdlgmvkveepfqglftqgmvlawtdfgpvevegsvvrlpeptr
irleipesalsledvrkmgaelrphedgtlhlwkpavmskskgngvmvgpfvkeqgadia
ritilfaappenemvwteegvqgawrflnriyrrvaedrealletsgvfqaealegkdre
lygklhetlkkvtedlealrfntaiaalmeflnalyeyrkdrpvtpvyrtairyylqmlf
pfaphlaeelwhwfwpdslfeagwpeldekalekdvvevavqvngrvrgtihipkdaple
varaealkvrnvrahlegkevvkeiyvpgkilnlvv

  • Chain 'B':
    No sequence available.

  • Chain 'D':
    Sequence, based on SEQRES records:
    >2v0gD (D:)
mekynphaieakwqrfweekgfmkakdlpggrgkqyvlvmfpypsgdlhmghlknytmgd
vlarfrrmqgyevlhpmgwdafglpaenaalkfgvhpkdwtyanirqakeslrlmgilyd
wdrevttcepeyyrwnqwiflkmwekglayrakglvnwcpkcqtvlaneqvvegrcwrhe
dtpvekreleqwylritayaerllkdleglnwpekvkamqrawigrsegaeilfpvegke
vripvfttrpdtlfgatflvlapehpltlelaapekreevlayveaakrkteierqaegr
ektgvflgayalnpatgeripiwtadyvlfgygtgaimavpahdqrdyefarkfglpikk
vierpgeplpeplerayeepgimvnsgpfdgteseegkrkviawleekglgkgrvtyrlr
dwlisrqrywgtpipmvhceacgvvpvpeeelpvllpdlkdvedirpkgkspleahpefy
ettcpkcggpakrdtdtmdtffdsswyylrytdphndrlpfdpekanawmpvdqyiggve
havlhllysrfftkflhdlgmvkveepfqglftqgmvlawtdfgpvevegsvvrlpeptr
irleipesalsledvrkmgaelrphedgtlhlwkpavmskskgngvmvgpfvkeqgadia
ritilfaappenemvwteegvqgawrflnriyrrvaedrealletsgvfqaealegkdre
lygklhetlkkvtedlealrfntaiaalmeflnalyeyrkdrpvtpvyrtairyylqmlf
pfaphlaeelwhwfwpdslfeagwpeldekalekdvvevavqvngrvrgtihipkdaple
varaealkvrnvrahlegkevvkeiyvpgkilnlvvrg

    Sequence, based on observed residues (ATOM records):
    >2v0gD (D:)
mekynphaieakwqrfweekgfmkakdlpggrgkqyvlvmfpypsgdlhmghlknytmgd
vlarfrrmqgyevlhpmgwdafglpaenaalkfgvhpkdwtyanirqakeslrlmgilyd
wdrevttcepeyyrwnqwiflkmwekglayrakglvnwcpkcqtvlaneqvvegrcwrhe
dtpvekreleqwylritayaerllkdleglnwpekvkamqrawigrsegaeilfpvegke
vripvfttrpdtlfgatflvlapehpltlelaapekreevlayveaakrkteierqaegr
ektgvflgayalnpatgeripiwtadyvlfgygtgaimavpahdqrdyefarkfglpikk
vierpgeplpeplerayeepgimvnsgpfdgteseegkrkviawleekglgkgrvtyrlr
dwlisrqrywgtpipmvhceacgvvpvpeeelpvllpdlkdvedirpkgkspleahpefy
ettcpkcggpakrdtdtmdtffdsswyylrytdphndrlpfdpekanawmpvdqyiggve
havlhllysrfftkflhdlgmvkveepfqglftqgmvlawtdfgpvevegsvvrlpeptr
irleipesalsledvrkmgaelrphedgtlhlwkpavmskskgngvmvgpfvkeqgadia
ritilfaappenemvwteegvqgawrflnriyrrvaedrealletsgvfqaealegkdre
lygklhetlkkvtedlealrfntaiaalmeflnalyeyrkdrpvtpvyrtairyylqmlf
pfaphlaeelwhwfwpdslfeagwpeldekalekdvvevavqvngrvrgtihipkdaple
varaealkvrnvrahlegkevvkeiyvpgkilnlvv

  • Chain 'F':
    No sequence available.