PDB entry 2v0c

View 2v0c on RCSB PDB site
Description: leucyl-trna synthetase from thermus thermophilus complexed with a sulphamoyl analogue of leucyl-adenylate in the synthetic site and an adduct of amp with 5-fluoro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole (an2690) in the editing site
Deposited on 2007-05-14, released 2007-07-03
The last revision was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: 0.181
AEROSPACI score: 0.51 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: aminoacyl-tRNA synthetase
    Species: THERMUS THERMOPHILUS [TaxId:274]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: LEU, LMS, ZN, ANZ, SO4, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >2v0cA (A:)
    mekynphaieakwqrfweekgfmkakdlpggrgkqyvlvmfpypsgdlhmghlknytmgd
    vlarfrrmqgyevlhpmgwdafglpaenaalkfgvhpkdwtyanirqakeslrlmgilyd
    wdrevttcepeyyrwnqwiflkmwekglayrakglvnwcpkcqtvlaneqvvegrcwrhe
    dtpvekreleqwylritayaerllkdleglnwpekvkamqrawigrsegaeilfpvegke
    vripvfttrpdtlfgatflvlapehpltlelaapekreevlayveaakrkteierqaegr
    ektgvflgayalnpatgeripiwtadyvlfgygtgaimavpahdqrdyefarkfglpikk
    vierpgeplpeplerayeepgimvnsgpfdgteseegkrkviawleekglgkgrvtyrlr
    dwlisrqrywgtpipmvhceacgvvpvpeeelpvllpdlkdvedirpkgkspleahpefy
    ettcpkcggpakrdtdtmdtffdsswyylrytdphndrlpfdpekanawmpvdqyiggve
    havlhllysrfftkflhdlgmvkveepfqglftqgmvlawtdfgpvevegsvvrlpeptr
    irleipesalsledvrkmgaelrphedgtlhlwkpavmskskgngvmvgpfvkeqgadia
    ritilfaappenemvwteegvqgawrflnriyrrvaedrealletsgvfqaealegkdre
    lygklhetlkkvtedlealrfntaiaalmeflnalyeyrkdrpvtpvyrtairyylqmlf
    pfaphlaeelwhwfwpdslfeagwpeldekalekdvvevavqvngavagtihipkdaple
    varaealkvrnvrahlegkevvkeiyvpgkilnlvvrg
    

    Sequence, based on observed residues (ATOM records):
    >2v0cA (A:)
    mekynphaieakwqrfweekgfmkakdlpgkqyvlvmfpypsgdlhmghlknytmgdvla
    rfrrmqgyevlhpmgwdafglpaenaalkfgvhpkdwtyanirqakeslrlmgilydwdr
    evttcepeyyrwnqwiflkmwekglayrakglvnwcpkcqtvlaneqvvegrcwrhedtp
    vekreleqwylritayaerllkdleglnwpekvkamqrawigrsegaeilfpvegkevri
    pvfttrpdtlfgatflvlapehpltlelaapekreevlayveaakrkteierqaegrekt
    gvflgayalnpatgeripiwtadyvlfgygtgaimavpahdqrdyefarkfglpikkvie
    rpgeplpeplerayeepgimvnsgpfdgteseegkrkviawleekglgkgrvtyrlrdwl
    isrqrywgtpipmvhceacgvvpvpeeelpvllpdlkdvedirpkgkspleahpefyett
    cpkcggpakrdtdtmdtffdsswyylrytdphndrlpfdpekanawmpvdqyiggvehav
    lhllysrfftkflhdlgmvkveepfqglftqgmvlawtdfgpvevegsvvrlpeptrirl
    eipesalsledvrkmgaelrphedgtlhlwkpavmskskgngvmvgpfvkeqgadiarit
    ilfaappenemvwteegvqgawrflnriyrrvaedrealletsgvfqaealegkdrelyg
    klhetlkkvtedlealrfntaiaalmeflnalyeyrkdrpvtpvyrtairyylqmlfpfa
    phlaeelwhwfwpdslfeagwpeldekale