PDB entry 2v00
View 2v00 on RCSB PDB site
Description: x-ray crystal structure of endothiapepsin complexed with compound 1
Class: hydrolase
Keywords: fragment hit, b- secretase, endothiapepsin, bace, zymogen, protease, hydrolase, isocytosine, alzheimer's disease, fragment-based lead generation, aspartyl protease, surrogate protein
Deposited on
2007-05-03, released
2007-12-04
The last revision prior to the SCOPe 2.01 freeze date was dated
2009-02-24, with a file datestamp of
2009-03-01.
Experiment type: XRAY
Resolution: 1.55 Å
R-factor: 0.17
AEROSPACI score: 0.62
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: endothiapepsin
Species: CRYPHONECTRIA PARASITICA [TaxId:5116]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.01: d2v00a_ - Heterogens: GOL, ACT, V15, HOH