PDB entry 2uzy

View 2uzy on RCSB PDB site
Description: structure of the human receptor tyrosine kinase met in complex with the listeria monocytogenes invasion protein inlb: low resolution, crystal form ii
Deposited on 2007-05-02, released 2007-08-07
The last revision was dated 2019-05-08, with a file datestamp of 2019-05-03.
Experiment type: XRAY
Resolution: 4 Å
R-factor: N/A
AEROSPACI score: 0.04 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: internalin b
    Species: LISTERIA MONOCYTOGENES [TaxId:169963]
    Database cross-references and differences (RAF-indexed):
    • PDB 2UZY (Start-2)
    • Uniprot P25147 (3-End)
  • Chain 'B':
    Compound: Hepatocyte growth factor receptor
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2UZY (719-End)
      • conflict (322)
    • Uniprot P08581 (Start-718)
  • Chain 'C':
    Compound: internalin b
    Species: LISTERIA MONOCYTOGENES [TaxId:169963]
    Database cross-references and differences (RAF-indexed):
    • PDB 2UZY (Start-2)
    • Uniprot P25147 (3-End)
  • Chain 'D':
    Compound: Hepatocyte growth factor receptor
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2UZY (719-End)
      • conflict (322)
    • Uniprot P08581 (Start-718)

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >2uzyA (A:)
gametitvptpikqifsddafaetikdnlkkksvtdavtqnelnsidqiiannsdiksvq
giqylpnvtklflngnkltdikplanlknlgwlfldenkvkdlsslkdlkklkslslehn
gisdinglvhlpqleslylgnnkitditvlsrltkldtlslednqisdivplagltklqn
lylsknhisdlralaglknldvlelfsqeclnkpinhqsnlvvpntvkntdgslvtpeii
sddgdyekpnvkwhlpeftnevsfifyqpvtigkakarfhgrvtqplke

    Sequence, based on observed residues (ATOM records):
    >2uzyA (A:)
metitvptpikqifsddafaetikdnlkkksvtdavtqnelnsidqiiannsdiksvqgi
qylpnvtklflngnkltdikplanlknlgwlfldenkvkdlsslkdlkklkslslehngi
sdinglvhlpqleslylgnnkitditvlsrltkldtlslednqisdivplagltklqnly
lsknhisdlralaglknldvlelfsqeclnkpinhqsnlvvpntvkntdgslvtpeiisd
dgdyekpnvkwhlpeftnevsfifyqpvtigkakarfhgrvtqplk

  • Chain 'B':
    Sequence, based on SEQRES records:
    >2uzyB (B:)
etreckealaksemnvnmkcqlpnftaetpiqnvilhehhiflgatnyiyvlneedlqkv
aeyktgpvlehpdcfpcqdcsskanlsggvwkdninmalvvdtyyddqliscgsvnrgtc
qrhvfphnhtadiqsevhcifspqieepsqcpdcvvsalgakvlssvkdrfinffvgnti
nssyfpdhplhsisvrrlketkdgfmfltdqsyidvlpefrdsypikyvhafesnnfiyf
ltvqretldaqtfhtriirfcsinsglhsymempleciltekrkkrstkkevfnilqaay
vskpgaqlarqigaslnddilfavfaqskpdsaepmdrsamcafpikyvndffnkivnkn
nvrclqhfygpnhehcfnrtllrnssgcearrdeyrtefttalqrvdlfmgqfsevllts
istfikgdltianlgtsegrfmqvvvsrsgpstphvnflldshpvspevivehtlnqngy
tlvitgkkitkiplnglgcrhfqscsqclsappfvqcgwchdkcvrseeclsgtwtqqic
lpaiykvfpnsapleggtrlticgwdfgfrrnnkfdlkktrvllgnesctltlsestmnt
lkctvgpamnkhfnmsiiisnghgttqystfsyvdpvitsispkygpmaggtlltltgny
lnsgnsrhisiggktctlksvsnsilecytpaqtistefavklkidlanretsifsyred
lhhhhhh

    Sequence, based on observed residues (ATOM records):
    >2uzyB (B:)
qlpnftaetpiqnvilhehhiflgatnyiyvlneedlqkvaeyktgpvlevwkdninmal
vvdtyyddqliscgsvnrgtcqrhvfphnhsevhcifspqieepsqcpdcvvsalgakvl
ssvkdrfinffvgntinssyplhsisvrrlketkdgfmfltdqsyidvlpefrdsypiky
vhafesnnfiyfltvqretldaqtfhtriirfcsinsglhsymempleciltevfnilqa
ayvskpgaqlarqigaslnddilfavfaqskpdsaepmdrsamcafpikyvndffnkirc
lqhfygpnhehcsgcedeyrtefttalqrvdlfmgqfsevlltsistfikgdltianlgt
segrfmqvvvsrsgpstphvnflldshpvspevivehtlnqngytlvitgkkitkiplng
lgcrhfqscsqclsappfvqcgwchdkcvrseeclsgtwtqqiclpaiykvfpnsapleg
gtrlticgwdfgfrrnnkfdlkktrvllgnesctltlsestmntlkctvgfnmsiiisng
hgttqystfsyvdpvitsispkygpmaggtlltltgnhisiggktctlksvsnsilecyt
paqtistefavklkidlanretsifsyred

  • Chain 'C':
    Sequence, based on SEQRES records:
    >2uzyC (C:)
gametitvptpikqifsddafaetikdnlkkksvtdavtqnelnsidqiiannsdiksvq
giqylpnvtklflngnkltdikplanlknlgwlfldenkvkdlsslkdlkklkslslehn
gisdinglvhlpqleslylgnnkitditvlsrltkldtlslednqisdivplagltklqn
lylsknhisdlralaglknldvlelfsqeclnkpinhqsnlvvpntvkntdgslvtpeii
sddgdyekpnvkwhlpeftnevsfifyqpvtigkakarfhgrvtqplke

    Sequence, based on observed residues (ATOM records):
    >2uzyC (C:)
metitvptpikqifsddafaetikdnlkkksvtdavtqnelnsidqiiannsdiksvqgi
qylpnvtklflngnkltdikplanlknlgwlfldenkvkdlsslkdlkklkslslehngi
sdinglvhlpqleslylgnnkitditvlsrltkldtlslednqisdivplagltklqnly
lsknhisdlralaglknldvlelfsqeclnkpinhqsnlvvpntvkntdgslvtpeiisd
dgdyekpnvkwhlpeftnevsfifyqpvtigkakarfhgrvtqplk

  • Chain 'D':
    Sequence, based on SEQRES records:
    >2uzyD (D:)
etreckealaksemnvnmkcqlpnftaetpiqnvilhehhiflgatnyiyvlneedlqkv
aeyktgpvlehpdcfpcqdcsskanlsggvwkdninmalvvdtyyddqliscgsvnrgtc
qrhvfphnhtadiqsevhcifspqieepsqcpdcvvsalgakvlssvkdrfinffvgnti
nssyfpdhplhsisvrrlketkdgfmfltdqsyidvlpefrdsypikyvhafesnnfiyf
ltvqretldaqtfhtriirfcsinsglhsymempleciltekrkkrstkkevfnilqaay
vskpgaqlarqigaslnddilfavfaqskpdsaepmdrsamcafpikyvndffnkivnkn
nvrclqhfygpnhehcfnrtllrnssgcearrdeyrtefttalqrvdlfmgqfsevllts
istfikgdltianlgtsegrfmqvvvsrsgpstphvnflldshpvspevivehtlnqngy
tlvitgkkitkiplnglgcrhfqscsqclsappfvqcgwchdkcvrseeclsgtwtqqic
lpaiykvfpnsapleggtrlticgwdfgfrrnnkfdlkktrvllgnesctltlsestmnt
lkctvgpamnkhfnmsiiisnghgttqystfsyvdpvitsispkygpmaggtlltltgny
lnsgnsrhisiggktctlksvsnsilecytpaqtistefavklkidlanretsifsyred
lhhhhhh

    Sequence, based on observed residues (ATOM records):
    >2uzyD (D:)
qlpnftaetpiqnvilhehhiflgatnyiyvlneedlqkvaeyktgpvlevwkdninmal
vvdtyyddqliscgsvnrgtcqrhvfphnhsevhcifsepsqcpdcvvsalgakvlssvk
drfinffvgntinssyplhsisvrrlketkdgfmfltdqsyidvlpefrdsypikyvhaf
esnnfiyfltvqretldaqtfhtriirfcsinsglhsymempleciltevfnilqaayvs
kpgaqlarqigaslnddilfavfaqskpdsaepmdrsamcafpikyvndffnkirclqhf
ygpndeyrtefttalqrvdlfmgqfsevlltsistfikgdltianlgtsegrfmqvvvsr
sgpstphvnflldshpvspevivehtlnqngytlvitgkkitkiplnglgcrhfqscsqc
lsappfvqcgwchdkcvrseeclsgtwtqqiclpaiykvfpnsapleggtrlticgwdfg
frrnnkfdlkktrvllgnesctltlsestmntlkctvgfnmsiiisnghgttqystfsyv
dpvitsispkygpmaggtlltltgnhisiggktctlksvsnsilecytpaqtistefavk
lkidlanretsifsyred