PDB entry 2uzx

View 2uzx on RCSB PDB site
Description: Structure of the human receptor tyrosine kinase Met in complex with the Listeria monocytogenes invasion protein InlB: Crystal form I
Class: signaling protein/receptor
Keywords: signaling protein/receptor, leucine rich repeat, receptor ectodomain, hepatocyte growth factor receptor, signaling protein, ATP-binding, transferase, polymorphism, glycoprotein, virulence factor, disease mutation, nucleotide-binding, transmembrane, proto-oncogene, phosphorylation, leucine-rich repeat, alternative splicing, tyrosine-protein kinase, chromosomal rearrangement, lrr, hgfr, kinase, membrane, receptor, internalin, signaling protein-receptor complex
Deposited on 2007-05-02, released 2007-08-07
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-05-08, with a file datestamp of 2019-05-03.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: N/A
AEROSPACI score: 0.14 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: internalin b
    Species: LISTERIA MONOCYTOGENES [TaxId:169963]
    Database cross-references and differences (RAF-indexed):
    • PDB 2UZX (Start-2)
    • Uniprot P25147 (3-End)
    Domains in SCOPe 2.08: d2uzxa1, d2uzxa2, d2uzxa3
  • Chain 'B':
    Compound: Hepatocyte growth factor receptor
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2UZX
      • conflict (322)
    • Uniprot P08581
  • Chain 'C':
    Compound: internalin b
    Species: LISTERIA MONOCYTOGENES [TaxId:169963]
    Database cross-references and differences (RAF-indexed):
    • PDB 2UZX (Start-2)
    • Uniprot P25147 (3-End)
    Domains in SCOPe 2.08: d2uzxc1, d2uzxc2, d2uzxc3
  • Chain 'D':
    Compound: Hepatocyte growth factor receptor
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2UZX
      • conflict (322)
    • Uniprot P08581

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2uzxA (A:)
gametitvptpikqifsddafaetikdnlkkksvtdavtqnelnsidqiiannsdiksvq
giqylpnvtklflngnkltdikplanlknlgwlfldenkvkdlsslkdlkklkslslehn
gisdinglvhlpqleslylgnnkitditvlsrltkldtlslednqisdivplagltklqn
lylsknhisdlralaglknldvlelfsqeclnkpinhqsnlvvpntvkntdgslvtpeii
sddgdyekpnvkwhlpeftnevsfifyqpvtigkakarfhgrvtqplke

    Sequence, based on observed residues (ATOM records): (download) 
    >2uzxA (A:)
ametitvptpikqifsddafaetikdnlkkksvtdavtqnelnsidqiiannsdiksvqg
iqylpnvtklflngnkltdikplanlknlgwlfldenkvkdlsslkdlkklkslslehng
isdinglvhlpqleslylgnnkitditvlsrltkldtlslednqisdivplagltklqnl
ylsknhisdlralaglknldvlelfsqeclnkpinhqsnlvvpntvkntdgslvtpeiis
ddgdyekpnvkwhlpeftnevsfifyqpvtigkakarfhgrvtqplk

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2uzxC (C:)
gametitvptpikqifsddafaetikdnlkkksvtdavtqnelnsidqiiannsdiksvq
giqylpnvtklflngnkltdikplanlknlgwlfldenkvkdlsslkdlkklkslslehn
gisdinglvhlpqleslylgnnkitditvlsrltkldtlslednqisdivplagltklqn
lylsknhisdlralaglknldvlelfsqeclnkpinhqsnlvvpntvkntdgslvtpeii
sddgdyekpnvkwhlpeftnevsfifyqpvtigkakarfhgrvtqplke

    Sequence, based on observed residues (ATOM records): (download) 
    >2uzxC (C:)
ametitvptpikqifsddafaetikdnlkkksvtdavtqnelnsidqiiannsdiksvqg
iqylpnvtklflngnkltdikplanlknlgwlfldenkvkdlsslkdlkklkslslehng
isdinglvhlpqleslylgnnkitditvlsrltkldtlslednqisdivplagltklqnl
ylsknhisdlralaglknldvlelfsqeclnkpinhqsnlvvpntvkntdgslvtpeiis
ddgdyekpnvkwhlpeftnevsfifyqpvtigkakarfhgrvtqplk

  • Chain 'D':
    No sequence available.