PDB entry 2uzo

View 2uzo on RCSB PDB site
Description: Crystal structure of human CDK2 complexed with a thiazolidinone inhibitor
Class: transferase
Keywords: transferase, ATP-binding, phosphorylation, cdk2, kinase, cyclin, mitosis, cell cycle, cell division, nucleotide-binding, serine/threonine-protein kinase, thiazolidinone ligand
Deposited on 2007-04-30, released 2007-06-26
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-01-30, with a file datestamp of 2019-01-25.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cell division protein kinase 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2uzoa_
  • Heterogens: C62, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2uzoA (A:)
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl

    Sequence, based on observed residues (ATOM records): (download) 
    >2uzoA (A:)
menfqkvekigegtygvvykarnkltgevvalkkirlvpstaireisllkelnhpnivkl
ldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrvlhr
dlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyystavdi
wslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwarq
dfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphl