PDB entry 2uzk

View 2uzk on RCSB PDB site
Description: Crystal structure of the human FOXO3a-DBD bound to DNA
Deposited on 2007-04-30, released 2008-05-13
The last revision was dated 2013-05-22, with a file datestamp of 2013-05-17.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.242
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: forkhead box protein o3a
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: 5'-d(*cp*tp*ap*tp*gp*tp*ap*ap*ap*cp*ap*ap*c)-3'
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
  • Chain 'C':
    Compound: forkhead box protein o3a
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2UZK (0-0)
    • Uniprot O43524 (1-End)
  • Chain 'D':
    Compound: 5'-d(*cp*tp*ap*tp*gp*tp*ap*ap*ap*cp*ap*ap*c)-3'
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
  • Chain 'E':
    Compound: 5'-d(*gp*tp*tp*gp*tp*tp*tp*ap*cp*ap*tp*ap*g)-3'
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
  • Chain 'F':
    Compound: 5'-d(*gp*tp*tp*gp*tp*tp*tp*ap*cp*ap*tp*ap*g)-3'
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
  • Heterogens: HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records:
    >2uzkA (A:)
    mgnlsyadlitraiesspdkrltlsqiyewmvrcvpyfkdkgdsnssagwknsirhnlsl
    hsrfmrvqnegtgksswwiinpdggksgkaprrravs
    

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    Sequence, based on SEQRES records:
    >2uzkC (C:)
    mgnlsyadlitraiesspdkrltlsqiyewmvrcvpyfkdkgdsnssagwknsirhnlsl
    hsrfmrvqnegtgksswwiinpdggksgkaprrravs
    

    Sequence, based on observed residues (ATOM records):
    >2uzkC (C:)
    mgnlsyadlitraiesspdkrltlsqiyewmvrcvpyfkdkgdsnssagwknsirhnlsl
    hsrfmrvqnegtgksswwiinpdggksgkapr
    

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    No sequence available.