PDB entry 2uyv

View 2uyv on RCSB PDB site
Description: l-rhamnulose-1-phosphate aldolase from escherichia coli (mutant q6y- e192a)
Class: lyase
Keywords: aggregation, zinc enzyme, fibrillation, metal-binding, oligomerization, interface design, surface mutation, 2-ketose degradation, protein-protein interface, zinc, lyase, aldolase, class II, rare sugar, cleavage of l-rhamnulose-1-phosphate to dihydroxyacetoneph bacterial l-rhamnose metabolism, rhamnose metabolism, protein engineering
Deposited on 2007-04-20, released 2008-01-15
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-07-24, with a file datestamp of 2019-07-19.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: rhamnulose-1-phosphate aldolase
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P32169 (0-273)
      • engineered mutation (5)
      • engineered mutation (191)
    Domains in SCOPe 2.08: d2uyva_
  • Chain 'B':
    Compound: rhamnulose-1-phosphate aldolase
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P32169 (0-273)
      • engineered mutation (5)
      • engineered mutation (191)
    Domains in SCOPe 2.08: d2uyvb_
  • Chain 'C':
    Compound: rhamnulose-1-phosphate aldolase
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P32169 (0-273)
      • engineered mutation (5)
      • engineered mutation (191)
    Domains in SCOPe 2.08: d2uyvc_
  • Chain 'D':
    Compound: rhamnulose-1-phosphate aldolase
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P32169 (0-273)
      • engineered mutation (5)
      • engineered mutation (191)
    Domains in SCOPe 2.08: d2uyvd_
  • Heterogens: TLA, ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2uyvA (A:)
mqnityswfvqgmikattdawlkgwdernggnltlrlddadiapyhdnfhqqpryiplsq
pmpllantpfivtgsgkffrnvqldpaanlgivkvdsdgagyhilwgltneavptselpa
hflshcerikatngkdrvimhchatnlialtyvlendtavftrqlwegsteclvvfpdgv
gilpwmvpgtdaigqataqemqkhslvlwpfhgvfgsgptldetfglidtaeksaqvlvk
vysmggmkqtisreelialgkrfgvtplasalal

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2uyvB (B:)
mqnityswfvqgmikattdawlkgwdernggnltlrlddadiapyhdnfhqqpryiplsq
pmpllantpfivtgsgkffrnvqldpaanlgivkvdsdgagyhilwgltneavptselpa
hflshcerikatngkdrvimhchatnlialtyvlendtavftrqlwegsteclvvfpdgv
gilpwmvpgtdaigqataqemqkhslvlwpfhgvfgsgptldetfglidtaeksaqvlvk
vysmggmkqtisreelialgkrfgvtplasalal

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2uyvC (C:)
mqnityswfvqgmikattdawlkgwdernggnltlrlddadiapyhdnfhqqpryiplsq
pmpllantpfivtgsgkffrnvqldpaanlgivkvdsdgagyhilwgltneavptselpa
hflshcerikatngkdrvimhchatnlialtyvlendtavftrqlwegsteclvvfpdgv
gilpwmvpgtdaigqataqemqkhslvlwpfhgvfgsgptldetfglidtaeksaqvlvk
vysmggmkqtisreelialgkrfgvtplasalal

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2uyvD (D:)
mqnityswfvqgmikattdawlkgwdernggnltlrlddadiapyhdnfhqqpryiplsq
pmpllantpfivtgsgkffrnvqldpaanlgivkvdsdgagyhilwgltneavptselpa
hflshcerikatngkdrvimhchatnlialtyvlendtavftrqlwegsteclvvfpdgv
gilpwmvpgtdaigqataqemqkhslvlwpfhgvfgsgptldetfglidtaeksaqvlvk
vysmggmkqtisreelialgkrfgvtplasalal