PDB entry 2uyu

View 2uyu on RCSB PDB site
Description: l-rhamnulose-1-phosphate aldolase from escherichia coli (mutant a88f-e192a)
Class: lyase
Keywords: aggregation, zinc enzyme, fibrillation, metal-binding, oligomerization, interface design, surface mutation, 2-ketose degradation, protein-protein interface, zinc, lyase, aldolase, class II, rare sugar, cleavage of l-rhamnulose-1-phosphate to dihydroxyacetoneph bacterial l-rhamnose metabolism, rhamnose metabolism, protein engineering
Deposited on 2007-04-20, released 2008-01-15
The last revision prior to the SCOPe 2.01 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.96 Å
R-factor: 0.204
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: rhamnulose-1-phosphate aldolase
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P32169 (0-273)
      • engineered mutation (87)
      • engineered mutation (191)
    Domains in SCOPe 2.01: d2uyua_
  • Chain 'E':
    Compound: rhamnulose-1-phosphate aldolase
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P32169 (0-273)
      • engineered mutation (87)
      • engineered mutation (191)
    Domains in SCOPe 2.01: d2uyue_
  • Heterogens: ZN, FE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2uyuA (A:)
mqnitqswfvqgmikattdawlkgwdernggnltlrlddadiapyhdnfhqqpryiplsq
pmpllantpfivtgsgkffrnvqldpafnlgivkvdsdgagyhilwgltneavptselpa
hflshcerikatngkdrvimhchatnlialtyvlendtavftrqlwegsteclvvfpdgv
gilpwmvpgtdaigqataqemqkhslvlwpfhgvfgsgptldetfglidtaeksaqvlvk
vysmggmkqtisreelialgkrfgvtplasalal

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2uyuE (E:)
mqnitqswfvqgmikattdawlkgwdernggnltlrlddadiapyhdnfhqqpryiplsq
pmpllantpfivtgsgkffrnvqldpafnlgivkvdsdgagyhilwgltneavptselpa
hflshcerikatngkdrvimhchatnlialtyvlendtavftrqlwegsteclvvfpdgv
gilpwmvpgtdaigqataqemqkhslvlwpfhgvfgsgptldetfglidtaeksaqvlvk
vysmggmkqtisreelialgkrfgvtplasalal