PDB entry 2uxz
View 2uxz on RCSB PDB site
Description: two-carbon-elongated hiv-1 protease inhibitors with a tertiary-alcohol-containing transition-state mimic
Class: hydrolase
Keywords: hiv-1, protease, hydrolase, inhibitor, aspartyl protease
Deposited on
2007-04-02, released
2008-05-20
The last revision prior to the SCOPe 2.04 freeze date was dated
2009-02-24, with a file datestamp of
2009-03-01.
Experiment type: XRAY
Resolution: 1.75 Å
R-factor: 0.202
AEROSPACI score: 0.52
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: hiv-1 protease
Species: HUMAN IMMUNODEFICIENCY VIRUS 1 [TaxId:11676]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d2uxza_ - Chain 'B':
Compound: hiv-1 protease
Species: HUMAN IMMUNODEFICIENCY VIRUS 1 [TaxId:11676]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d2uxzb_ - Heterogens: HI1, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>2uxzA (A:)
pqitlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
qilieicghkaigtvlvgptpvniigrnlltqigctlnf
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>2uxzB (B:)
pqitlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
qilieicghkaigtvlvgptpvniigrnlltqigctlnf